Beneficial metabolic phenotypes caused by loss-of-function APOC3 mutations

Clinical Genetics

Volumn 87, Issue 1, 2015, Pages 31-32

  Gibson, W T ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C3; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ALLELE; APOC3 GENE; ARTICLE; CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; GENE; GENETIC EPIDEMIOLOGY; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HEART PROTECTION; HUMAN; LOSS OF FUNCTION MUTATION; PCSK9 GENE; PERSONALIZED MEDICINE; PHENOTYPE; SANGER SEQUENCING; BLOOD; FEMALE; GENETICS; HEART MUSCLE ISCHEMIA; ISCHEMIA; MALE; MUTATION;

APOLIPOPROTEIN C-III; CORONARY DISEASE; FEMALE; HUMANS; ISCHEMIA; MALE; MUTATION; MYOCARDIAL ISCHEMIA; TRIGLYCERIDES;

EID: 84919425600     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/cge.12483     Document Type: Article

References (3)

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2. Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006: 354 (12): 1264-1272.
3. Nierman MC, Rip J, Kuivenhoven JA et al. Carriers of the frequent lipoprotein lipase S447X variant exhibit enhanced postprandial apoprotein B-48 clearance. Metabolism 2005: 54 (11): 1499-1503.