Bilateral or unilateral stimulation for baroreflex activation therapy

Hypertension

Volumn 65, Issue 1, 2015, Pages 187-192

  De Leeuw, Peter W ^a   Alnima, Teba ^a   Lovett, Eric ^b   Sica, Domenic ^c   Bisognano, John ^d   Haller, Hermann ^e   Kroon, Abraham A ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CVRX INC   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Hemodynamics; Hypertension; Pressoreceptors; Sympathetic Nervous System

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ADULT; ARTICLE; BAROREFLEX ACTIVATION THERAPY; BLOOD PRESSURE; CAROTID SINUS PRESSORECEPTOR REFLEX; DEVICE THERAPY; ELECTRODE; FEMALE; HEART RATE; HUMAN; IMPLANTABLE CAROTID SINUS STIMULATOR; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; RESISTANT HYPERTENSION; RESTING HEART RATE; STIMULATION; TREATMENT OUTCOME; CLINICAL TRIAL; CONTROLLED STUDY; DEVICES; ELECTRODE IMPLANT; ELECTROSTIMULATION THERAPY; EQUIPMENT DESIGN; FOLLOW UP; HYPERTENSION; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESSORECEPTOR; PRESSORECEPTOR REFLEX; TIME;

BAROREFLEX; BLOOD PRESSURE; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; EQUIPMENT DESIGN; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PRESSORECEPTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84919417426     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.04492     Document Type: Article

References (9)

1. Scheffers IJ, Kroon AA, Schmidli J, et al. Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol. 2010;56:1254-1258.
2. Bisognano JD, Bakris G, Nadim MK, Sanchez L, Kroon AA, Schafer J, de Leeuw PW, Sica DA. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial. J Am Coll Cardiol. 2011;58:765-773.
3. Heusser K, Tank J, Engeli S, Diedrich A, Menne J, Eckert S, Peters T, Sweep FC, Haller H, Pichlmaier AM, Luft FC, Jordan J. Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension. 2010;55:619-626.
4. Wustmann K, Kucera JP, Scheffers I, Mohaupt M, Kroon AA, de Leeuw PW, Schmidli J, Allemann Y, Delacrtaz E. Effects of chronic baroreceptor stimulation on the autonomic cardiovascular regulation in patients with drug-resistant arterial hypertension. Hypertension. 2009;54:530-536.
5. Hoppe UC, Brandt MC, Wachter R, Beige J, Rump LC, Kroon AA, Cates AW, Lovett EG, Haller H. Minimally invasive system for baroreflex activation therapy chronically lowers blood pressure with pacemaker-like safety profile: results from the Barostim neo trial. J Am Soc Hypertens. 2012;6:270-276.
6. Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM. Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008;51:1403-1419.
7. Tafil-Klawe M, Raschke F, Hildebrandt G. Functional asymmetry in carotid sinus cardiac reflexes in humans. Eur J Appl Physiol Occup Physiol. 1990;60:402-405.
8. Diedrich A, Porta A, Barbic F, Brychta RJ, Bonizzi P, Diedrich L, Cerutti S, Robertson D, Furlan R. Lateralization of expression of neural sympathetic activity to the vessels and effects of carotid baroreceptor stimulation. Am J Physiol Heart Circ Physiol. 2009;296:H1758-H1765.
9. Furlan R, Diedrich A, Rimoldi A, Palazzolo L, Porta C, Diedrich L, Harris PA, Sleight P, Biagioni I, Robertson D, Bernardi L. Effects of unilateral and bilateral carotid baroreflex stimulation on cardiac and neural sympathetic discharge oscillatory patterns. Circulation. 2003;108:717-723.