A randomized placebo controlled trial to evaluate the effects of butamirate and dextromethorphan on capsaicin induced cough in healthy volunteers

British Journal of Clinical Pharmacology

Volumn 78, Issue 6, 2014, Pages 1272-1280

  Faruqi, Shoaib ^a   Wright, Caroline ^a   Thompson, Rachel ^a   Morice, Alyn H ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

Butamirate; Capsaicin; Cough sensitivity; Dextromethorphan

Indexed keywords

BUTAMIRATE CITRATE; CAPSAICIN; DEXTROMETHORPHAN; PLACEBO; ARYLBUTYRIC ACID DERIVATIVE; BUTAMIRATE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; COUGHING; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG HALF LIFE; DRUG INDUCED DISEASE; DRUG INDUCED HEADACHE; FEMALE; HUMAN; LIMIT OF QUANTITATION; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NAUSEA; PHARMACODYNAMICS; PLASMA CONCENTRATION-TIME CURVE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SOMNOLENCE; TIME TO MAXIMUM PLASMA CONCENTRATION; CHEMICALLY INDUCED; COUGH; MIDDLE AGED; NORMAL HUMAN;

ADULT; CAPSAICIN; COUGH; CROSS-OVER STUDIES; DEXTROMETHORPHAN; FEMALE; HEALTHY VOLUNTEERS; HUMANS; MALE; MIDDLE AGED; PHENYLBUTYRATES;

EID: 84919340561     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12458     Document Type: Article

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