HCV E2 core structures and mAbs: Something is still missing

Drug Discovery Today

Volumn 19, Issue 12, 2014, Pages 1964-1970

  Castelli, Matteo ^a   Clementi, Nicola ^a   Sautto, Giuseppe A ^a   Pfaff, Jennifer ^b   Kahle, Kristen M ^b   Barnes, Trevor ^b   Doranz, Benjamin J ^b   Dal Peraro, Matteo ^c,d   Clementi, Massimo ^a   Burioni, Roberto ^a   Mancini, Nicasio ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b Integral Molecular   (United States)

^c Chemical Engineering and Biochemistry Section   (Switzerland)

^d SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DISULFIDE; GLYCOPROTEIN E2; HEPATITIS VACCINE; HUMAN MONOCLONAL ANTIBODY; VACCINE; CYSTEINE; GLYCOPROTEIN E2, HEPATITIS C VIRUS; MONOCLONAL ANTIBODY; VIRUS ENVELOPE PROTEIN;

CIRCULAR DICHROISM; COMPARATIVE STUDY; HEPATITIS C VIRUS; HUMAN; IMMUNOLOGY; INFRARED SPECTROSCOPY; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RECEPTOR BINDING; REVIEW; VACCINATION; VIRUS ATTACHMENT; VIRUS ENTRY; X RAY CRYSTALLOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HEPACIVIRUS; METABOLISM; PATHOGENICITY; PROTEIN CONFORMATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CYSTEINE; DISULFIDES; HEPACIVIRUS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; VIRAL ENVELOPE PROTEINS;

EID: 84919332929     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2014.08.011     Document Type: Review

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