Paeoniflorin Upregulates β-Defensin-2 Expression in Human Bronchial Epithelial Cell Through the p38 MAPK, ERK, and NF-κB Signaling Pathways

Inflammation

Volumn 37, Issue 5, 2014, Pages 1468-1475

  Gan, Yuying ^a   Cui, Xuefan ^a   Ma, Ting ^a   Liu, Yanliang ^a   Li, Amin ^a   Huang, Mao ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

16HBEC; ERK; human defensin 2; NF B; p38 MAPK; paeoniflorin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA DEFENSIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PAEONIFLORIN; PYRROLIDINE DITHIOCARBAMATE; STRESS ACTIVATED PROTEIN KINASE; BETA DEFENSIN; DEFB4A PROTEIN, HUMAN; GLUCOSIDE; TERPENE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN BRONCHIAL EPITHELIAL CELL; HUMAN CELL; IMMUNOFLUORESCENCE TEST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PAEONIA; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA; TRANSFORMED CELL LINE;

BACTERIA (MICROORGANISMS); PAEONIA;

BETA-DEFENSINS; CELL LINE, TRANSFORMED; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCOSIDES; HUMANS; MAP KINASE SIGNALING SYSTEM; MONOTERPENES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PAEONIA; RESPIRATORY MUCOSA; UP-REGULATION;

EID: 84918834228     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9872-7     Document Type: Article

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