Concomitant Seminal Vesicle Invasion in pT4a Urothelial Carcinoma of the Bladder with Contiguous Prostatic Infiltration is an Adverse Prognosticator for Cancer-Specific Survival after Radical Cystectomy

Annals of Surgical Oncology

Volumn 21, Issue 12, 2014, Pages 4034-4040

  May, Matthias ^a   Brookman May, Sabine ^b   Burger, Maximilian ^c   Gilfrich, Christian ^a   Fritsche, Hans Martin ^c   Rink, Michael ^d   Chun, Felix ^d   Fisch, Margit ^d   Roghmann, Florian ^e   Noldus, Joachim ^e   Mayr, Roman ^f   Pycha, Armin ^f   Novotny, Vladimir ^g   Wirth, Manfred ^g   Vallo, Stefan ^h   Haferkamp, Axel ^h   Roigas, Jan ⁱ   Brisuda, Antonin ^j   Stredele, Regina ^k   Volkmer, Björn ^k   Dechet, Christopher ^l   Schnabel, Marco ^c   Denzinger, Stefan ^c   Stief, Christian G ^b   Bastian, Patrick J ^m   Aziz, Atiqullah ^d   more..

^a Department of Urology   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

^f CENTRAL HOSPITAL OF BOLZANO   (Italy)

^g UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^h GOETHE UNIVERSITY   (Germany)

ⁱ VIVANTES KLINIKUM NEUKÖLLN   (Germany)

^j UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^k Department of Pathology   (Germany)

^l UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^m Golzheim Paracelsus Clinic   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CANCER INFILTRATION; CANCER PROGNOSIS; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CONCOMITANT SEMINAL VESICLE INVASION; CONTIGUOUS PROSTATIC STROMAL INFILTRATION; CONTROLLED STUDY; CYSTECTOMY; FOLLOW UP; GENERAL PATHOLOGICAL PARAMETERS; HUMAN; HUMAN TISSUE; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; SOFT TISSUE SURGICAL MARGIN; TRANSITIONAL CELL CARCINOMA; TUMOR INVASION; UROTHELIAL CARCINOMA OF THE BLADDER; ADVERSE EFFECTS; CARCINOMA, TRANSITIONAL CELL; COMPARATIVE STUDY; FEMALE; MIDDLE AGED; MORTALITY; NEOPLASM RECURRENCE, LOCAL; PATHOLOGY; POSTOPERATIVE COMPLICATION; PROGNOSIS; PROSTATE; SEMINAL VESICLE; SURVIVAL RATE; URINARY BLADDER NEOPLASMS;

AGED; CARCINOMA, TRANSITIONAL CELL; CYSTECTOMY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; PROSTATE; SEMINAL VESICLES; SURVIVAL RATE; URINARY BLADDER NEOPLASMS;

EID: 84918818453     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-3827-y     Document Type: Article

References (15)

1. Witjes JA, Compérat E, Cowan NC, et al. EAU guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2013 guidelines. Eur Urol. 2014;65:778–92.
2. Niegisch G, Albers P. Which patients benefit the most from neoadjuvant chemotherapy in advanced bladder cancer? Curr Opin Urol. 2011;21:434–9.
3. Feifer AH, Taylor JM, Tarin TV, Herr HW. Maximizing cure for muscle-invasive bladder cancer: integration of surgery and chemotherapy. Eur Urol. 2011;59:978–84.
4. Nuhn P, May M, Sun M, et al. External validation of postoperative nomograms for prediction of all-cause mortality, cancer-specific mortality, and recurrence in patients with urothelial carcinoma of the bladder. Eur Urol. 2012;61:58–64.
5. Tilki D, Svatek RS, Karakiewicz PI, et al. Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients. J Urol. 2010;183:1757–63.
6. Liberman D, Alasker A, Sun M, et al. Radical cystectomy for patients with pT4 urothelial carcinoma in a large population-based study. BJU Int. 2011;107:905–11.
7. Greene FL, Gospodarowicz M, Wittekend C. American Joint Committee on Cancer (AJCC) staging manual. 7th ed. Philadalphia: Springer; 2009.
8. Volkmer BG, Küfer R, Maier S, et al. Outcome in patients with seminal vesicle invasion after radical cystectomy. J Urol. 2003;169:1299–302.
9. Daneshmand S, Stein JP, Lesser T, et al. Prognosis of seminal vesicle involvement by transitional cell carcinoma of the bladder. J Urol. 2004;172:81–4.
10. You D, Kim SC, Jeong IG, et al. Urothelial carcinoma of the bladder with seminal vesicle invasion: prognostic significance. BJU Int. 2010;106:1657–61.
11. Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15:361–87.
12. May M, Bastian PJ, Brookman-May S, et al. Gender-specific differences in cancer-specific survival after radical cystectomy for patients with urothelial carcinoma of the urinary bladder in pathologic tumor stage T4a. Urol Oncol. 2011;31:1141–7.
13. Donat SM, Genega EM, Herr HW, Reuter VE. Mechanisms of prostatic stromal invasion in patients with bladder cancer: clinical significance. J Urol. 2001;165:1117–20.
14. Ro JY, Ayala AG, el-Naggar A, Wishnow KI. Seminal vesicle involvement by in situ and invasive transitional cell carcinoma of the bladder. Am J Surg Pathol. 1987;11:951–8.
15. Montie JE, Wojno K, Klein E, Pearsall C, Levin H. Transitional cell carcinoma in situ of the seminal vesicles: 8 cases with discussion of pathogenesis, and clinical and biological implications. J Urol. 1997;158:1895–8.