Pathophysiological and pharmacological implications of elucidating the molecular bases of the interaction between HBV and the bile acid transporter NTCP

Annals of Hepatology

Volumn 14, Issue 1, 2015, Pages 143-144

  Romero, Marta R ^a   Monte, Maria J ^a   Marin, Jose J G ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BILE ACID; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; MYRCLUDEX B; SODIUM BILE ACID COTRANSPORTER; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BILE ACID BLOOD LEVEL; BILE ACID SYNTHESIS; BIOACCUMULATION; BIOTRANSFORMATION; CELLULAR DISTRIBUTION; CHIMERA; DRUG PROTEIN BINDING; GENE; GENETIC VARIABILITY; HEPATITIS B; HEPATITIS B VIRUS; LIPID METABOLISM; LIVER BIOPSY; LIVER CELL; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MOUSE MODEL; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SLC10A1 GENE; TISSUE DISTRIBUTION; UPREGULATION; VIRUS ENTRY; VIRUS INHIBITION; VIRUS PARTICLE; VIRUS VIRULENCE; ANIMAL; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL; HEPATITIS B; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS;

EID: 84918815112     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1665-2681(19)30814-2     Document Type: Article

References (11)

1. Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, et al. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. eLife 2012: 1: e00049.
2. +/bile acid cotransporter. J Clin Invest 1994: 93: 1326-31.
3. Schulze A, Mills K, Weiss TS, Urban S. Hepatocyte polarization is essential for the productive entry of the hepatitis B virus. Hepatology 2012: 55: 373-83.
4. Jorquera F, Monte MJ, Guerra J, Sanchez-Campos S, Merayo JA, Olcoz JL, Gonzalez-Gallego J, et al. Usefulness of combined measurement of serum bile acids and ferritin as additional prognostic markers to predict failure to reach sustained response to antiviral treatment in chronic hepatitis C. J Gastroenterol Hepatol 2005: 20: 547-54.
5. Shieh YS, Chang YS, Hong JR, Chen LJ, Jou LK, Hsu CC, Her GM. Increase of hepatic fat accumulation by liver specific expression of Hepatitis B virus X protein in zebrafish. Biochim Biophys Acta 2010: 1801: 721-30.
6. Cho HK, Kim SY, Yoo SK, Choi YH, Cheong J. Fatty acids increase hepatitis B virus X protein stabilization and HBxinduced inflammatory gene expression. FEBS J 2014: 281: 2228-39.
7. Le Seyec J, Chouteau P, Cannie I, Guguen-Guillouzo C, Gripon P. Infection process of the hepatitis B virus depends on the presence of a defined sequence in the pre-S1 domain. J Virol 1999: 73: 2052-7.
8. Monte MJ, Marin JJ, Antelo A, Vazquez-Tato J. Bile acids: chemistry, physiology, and pathophysiology. World J Gastroenterol 2009: 15: 804-16.
9. +/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology 1996: 110: 199-209.
10. Erlinger S. NTCP deficiency: A new inherited disease of bile acid transport. Clin Res Hepatol Gastroenterol 2014: (in press).
11. +-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition. J Biol Chem 2004: 279: 7213-22.