Risk factors of treatment default and death among tuberculosis patients in a resource-limited setting

Asian Pacific Journal of Tropical Medicine

Volumn 7, Issue 12, 2014, Pages 977-984

  Alobu, Isaac ^a   Oshi, Sarah N ^b   Oshi, Daniel C ^b   Ukwaja, Kingsley N ^c  

^a Ministry of Health   (Nigeria)

^b Centre for Development and Reproductive Health   (Nigeria)

^c Federal Teaching Hospital   (Nigeria)

Author keywords

Epidemiology; Health services; Mortality; Nigeria; Treatment default; Treatment outcome; Tuberculosis

Indexed keywords

ETHAMBUTOL; ISONIAZID; PYRAZINAMIDE; RIFAMPICIN;

ADULT; AGE; ARTICLE; COHORT ANALYSIS; DEATH; EXTRAPULMONARY TUBERCULOSIS; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; NIGERIA; RETROSPECTIVE STUDY; RISK FACTOR; RURAL POPULATION; TREATMENT DURATION; TUBERCULOSIS;

EID: 84918779992     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(14)60172-3     Document Type: Article

References (34)

1. World Health Oragnization Definitions of tuberculosis cases and treatment outcomes 2013, World Health Organization, Geneva, Switzerland.
2. Verver S, Warren RM, Beyers N, Richardson M, van der Spuy GD, Borgdorff MW, et al. Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am J Respir Crit Care Med 2005, 171(12):1430-1435.
3. O'Brien JK, Sandman LA, Kreiswirth BN, Rom WN, Schluger NW DNA fingerprints from Mycobacterium tuberculosis isolates of patients confined for therapy noncompliance show frequent clustering. Chest 1997, 112(2):387-392.
4. Weis SE, Slocum PC, Blais FX, King B, Nunn M, Matney GB, et al. The effect of directly observed therapy on the rates of drug resistance and relapse in tuberculosis. N Engl J Med 1994, 330(17):1179-1184.
5. Federal Ministry of Health, Nigeria National TB and leprosy control program, National drug-resistant tuberculosis prevalence survey 2012, Federal Ministry of Health, Abuja, Nigeria.
6. World Health Organization Global tuberculosis control: WHO report 2013 2013, World Health Organisation, Geneva, Switzerland.
7. Ifebunadu NA, Ukwaja KN Tuberculosis treatment default in a large tertiary care hospital in urban Nigeria: Prevalence, trend, timing and predictors. J Infect Public Health 2012, 5(5):340-345.
8. Ibrahim LM, Hadejia IS, Nguku P, Dankoli R, Waziri NE, Akhimien MO, et al. Factors associated with interruption of treatment among pulmonary tuberculosis patients in Plateau State, Nigeria. 2011. Pan Afr Med J 2014, 17:78.
9. Tachfouti N, Slama K, Berraho M, Elfakir S, Benjelloun MC, El Rhazi K, et al. Determinants of tuberculosis treatment default in Morocco: results from a national cohort study. Pan Afr Med J 2013, 14:121.
10. Rutherford ME, Hill PC, Maharani W, Sampurno H, Ruslami R Risk factors for treatment default among adult tuberculosis patients in Indonesia. Int J Tuberc Lung Dis 2013, 17(10):1304-1309.
11. Jenkins HE, Ciobanu A, Plesca V, Crudu V, Galusca I, Soltan V, et al. Risk factors and timing of default from treatment for non-multidrug-resistant tuberculosis in Moldova. Int J Tuberc Lung Dis 2013, 17(3):373-380.
12. Muture BN, Keraka MN, Kimuu PK, Kabiru EW, Ombeka V, Oguya F Factors associated with default from treatment among tuberculosis patients in Nairobi province, Kenya: a case control study. BMC Public Health 2011, 11:696.
13. Garrido Mda S, Penna ML, Perez-Porcuna TM, de Souza AB, Marreiro Lda S, Albuquerque BC, et al. Factors associated with tuberculosis treatment default in an endemic area of the Brazilian Amazon: a case control-study. PLoS One 2012, 7:e39134.
14. Sendagire I, Schim Van der Loeff M, Kambugu A, Konde-Lule J, Cobelens F Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study. PLoS One 2012, 7:e35908.
15. Vijay S, Kumar P, Chauhan LS, Vollepore BH, Kizhakkethil UP, Rao SG Risk factors associated with default among new smear positive TB patients treated under DOTS in India. PLoS One 2010, 5:e10043.
16. Hasker E, Khodjikhanov M, Usarova S, Asamidinov U, Yuldashova U, Van der Werf MJ, et al. Default from tuberculosis treatment in Tashkent. Uzbekistan; who are these defaulters and why do they default?. BMC Infect Dis 2008, 8:97.
17. Nahid P, Jarlsberg LG, Rudoy I, de Jong BC, Unger A, Kawamura LM, et al. Factors associated with mortality in patients with drug-susceptible pulmonary tuberculosis. BMC Infect Dis 2011, 11:1.
18. Burton NT, Forson A, Lurie MN, Kudzawu S, Kwarteng E, Kwara A Factors associated with mortality and default among patients with tuberculosis attending a teaching hospital clinic in Accra, Ghana. Trans R Soc Trop Med Hyg 2011, 105(12):675-682.
19. Waitt CJ, Squire SB A systematic review of risk factors for death in adults during and after tuberculosis treatment. Int J Tuberc Lung Dis 2011, 15(7):871-885.
20. Horne DJ, Hubbard R, Narita M, Exarchos A, Park DR, Goss CH Factors associated with mortality in patients with tuberculosis. BMC Infect Dis 2010, 10:258.
21. Kruk ME, Schwalbe NR, Aguiar CA Timing of default from tuberculosis treatment: a systematic review. Trop Med Int Health 2008, 13(5):703-712.
22. World Health Organisation Treatment of tuberculosis guidelines 2010, World Health Organization, Geneva, Switzerland. Fourth Edition.
23. Federal Ministry of Health, Nigeria National Tuberculosis and Leprosy Control Programme: workers manual 2010, Federal Ministry of Health, Abuja, Nigeria. Revised 5th ed.
24. National Population Commission The 2006 population and housing census of the Federal Republic of Nigeria. Priority Tables 2009, Volume I. The National Population Commission, Abuja, Nigeria.
25. Ukwaja KN, Alobu I, Ifebunandu NA, Osakwe PC Trend in case detection rate for all tuberculosis cases notified in Ebonyi, Southeastern Nigeria during 1999 - 2009. Pan Afr Med J 2013, 16:11.
26. Ukwaja K, Alobu I, Ifebunandu N, Osakwe C, Igwenyi C From DOTS to the stop TB strategy: DOTS coverage and trend of tuberculosis notification in Ebonyi, southeastern Nigeria, 1998-2009. Pan Afr Med J 2011, 2:12.
27. Abuaku B, Tan H, Li X, Chen M, Huang X Treatment default and death among tuberculosis patients in Hunan, China. Scand J Infect Dis 2010, 42(4):281-287.
28. Anunnatsiri S, Chetchotisakd P, Wanke C Factors associated with treatment outcomes in pulmonary tuberculosis in northeastern Thailand. Southeast Asian J Trop Med Public Health 2005, 36(2):323-330.
29. Ukwaja KN, Modebe O, Igwenyi C, Alobu I The economic burden of tuberculosis care for patients and households in Africa: a systematic review. Int J Tuberc Lung Dis 2012, 16(6):733-739.
30. Ukwaja KN, Alobu I, Nweke CO, Onyenwe EC Healthcare-seeking behavior, treatment delays and its determinants among pulmonary tuberculosis patients in rural Nigeria: A cross-sectional study. BMC Health Serv Res 2013, 13:25.
31. Martinson NA, Karstaedt A, Venter WD, Omar T, King P, Mbengo T, et al. Causes of death in hospitalized adults with a premortem diagnosis of tuberculosis: an autopsy study. AIDS 2007, 21(15):2043-2050.
32. Suthar AB, Granich R, Mermin J, Van Rie A Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: a systematic review and meta-analysis. Bull World Health Organ 2012, 90(2):128C-138C.
33. Manosuthi W, Chottanapand S, Thongyen S, Chaovavanich A, Sungkanuparph S Survival rate and risk factors of mortality among HIV/tuberculosis-coinfected patients with and without antiretroviral therapy. J Acquir Immune Defic Syndr 2006, 43(1):42-46.
34. Abdool Karim SS, Naidoo K, Grobler A, Padayatchi N, Baxter C, Gray A, et al. Timing of initiation of antiretroviral drugs during tuberculosis therapy. N Engl J Med 2010, 362(8):697-706.