Influence of Helicobacter pylori infection on metabolic parameters and body composition of dyslipidemic patients

Internal and Emergency Medicine

Volumn 9, Issue 7, 2014, Pages 767-772

  Moretti, Elena ^a   Gonnelli, Stefano ^b   Campagna, Mariastella ^b   Nuti, Ranuccio ^b   Collodel, Giulia ^a   Figura, Natale ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

BMI; CagA; Dyslipidemia; Fat mass; Glucose; H. pylori infection; HDL cholesterol

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI;

ADULT; BODY COMPOSITION; COMPLICATION; DYSLIPIDEMIA; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOGENICITY;

ADULT; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BODY COMPOSITION; DYSLIPIDEMIAS; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED;

EID: 84918773125     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-013-1043-6     Document Type: Article

References (48)

1. Graham DY (1989) Campylobacterpylori and peptic ulcer disease. Gastroenterology 96:615–625
2. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG (1991) Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 338:1175–1176
3. Parsonnet J (1993) Helicobacter pylori and gastric cancer. Gastroenterol Clin North Am 22:89–104
4. Mendall MA, Goggin PM, Molineaux N, Levy J, Toosy T, Strachan D, Camm AJ, Northfield TC (1994) Relation of Helicobacter pylori infection and coronary heart disease. Br Heart J 71:437–439
5. Patel P, Carrington D, Strachan DP, Leatham E, Goggin P, Northfield TC, Mendall MA (1994) Fibrinogen: a link between chronic infection and coronary heart disease. Lancet 343:1634–1635
6. Tebbe B, Geilen CC, Schulzke JD, Bojarski C, Radenhausen M, Orfanos CE (1996) Helicobacter pylori infection and chronic urticaria. J Am Acad Dermatol 34:685–686
7. Van Lente F (2000) Markers of inflammation as predictors in cardiovascular disease. Clin Chim Acta 293:31–52
8. Niemelä S, Karttunen T, Korhonen T, Laara E, Karttunen R, Ikaheimo M, Kesaniemi YA (1996) Could Helicobacter pylori infection increase the risk of coronary heart disease by modifying serum lipid concentrations? Heart 75:573–575
9. Hoffmeister A, Rothenbacher D, Bode G, Persson K, März W, Nauck MA, Brenner H, Hombach V, Koenig W (2001) Current infection with Helicobacter pylori but not seropositivity to Chlamydia pneumoniae or cytomegalovirus is associated with an atherogenic modified lipid profile. Arterioscler Thromb Vasc Biol 21:427–432
10. Murray LJ, Bamford KB, O’Reilly DP, McCrum EE, Evans AE (1995) Helicobacter pylori infection: relation with cardiovascular risk factors, ischaemic heart disease, and social class. Br Heart J 74:497–501
11. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P (1999) Association of Helicobacter pylori infection with elevated serum lipids. Atherosclerosis 142:207–210
12. Zhu J, Quyyumi AA, Muhlestein JB, Nieto FJ, Horne BD, Zalles-Ganley A, Anderson JL, Epstein SE (2002) Lack of association of Helicobacter pylori infection with coronary artery disease and frequency of acute myocardial infarction or death. Am J Cardiol 89:155–158
13. Arslan E, Atilgan H, Yavaşoğlu I (2009) The prevalence of Helicobacter pylori in obese subjects. Eur J Intern Med 20:695–697. doi:10.1016/j.ejim.2009.07.013
14. Ioannou GN, Weiss NS, Kearney DJ (2005) Is Helicobacter pylori seropositivity related to body mass index in the United States? Aliment Pharmacol Ther 21:765–772
15. Covacci A, Censini S, Bugnoli M, Petracca R, Burroni D, Macchia G, Massone A, Papini E, Xiang Z, Figura N, Rappuoli R (1993) Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 90:5791–5795
16. Xiang Z, Bugnoli M, Ponzetto A, Morgando A, Figura N, Covacci A, Petracca R, Pennatini C, Censini S, Armellini D, Rappuoli R (1993) Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) of Helicobacter pylori. Eur J Clin Microbiol Infect Dis 12:739–745
17. Kosunen TU, Seppälä K, Sarna S, Sipponen P (1992) Diagnostic value of decreasing IgG, IgA, and IgM antibody titres after eradication of Helicobacterpylori. Lancet 339:893–895
18. Ching CK, Wong BC, Kwok E, Ong L, Covacci A, Lam SK (1996) Prevalence of CagA-bearing Helicobacter pylori strains detected by the anti-CagA assay in patients with peptic ulcer disease and in controls. Am J Gastroenterol 91:949–953
19. Figura N, Franceschi F, Santucci A, Bernardini G, Gasbarrini G, Gasbarrini A (2010) Extragastric manifestations of Helicobacter pylori infection. Helicobacter 15:60–68
20. Jia EZ, Zhao FJ, Hao B, Zhu TB, Wang LS, Chen B, Cao KJ, Huang J, Ma WZ, Yang ZJ, Zhang G (2009) Helicobacter pylori infection is associated with decreased serum levels of high density lipoprotein, but not with the severity of coronary atherosclerosis. Lipids Health Dis 8:59. doi:10.1186/1476-511X-8-59
21. Kanbay M, Gür G, Yücel M, Yilmaz U, Boyacioğlu S (2005) Does eradication of Helicobacterpylori infection help normalize serum lipid and CRP levels? Dig Dis Sci 50:1228–1231
22. Gallin JL, Kaye D, O’Leary WM (1969) Serum lipid in infection. N Engl J Med 281:1081–1086
23. Alvarez C, Ramos A (1986) Lipids, lipoproteins, and apoproteins in serum during infection. Clin Chem Res 32:142–145
24. Grunfeld C, Gulli R, Moser AH, Gavin LA, Feingold KR (1989) Effect of tumour necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat. J Lipid Res 30:579–585
25. Ekesbo R, Nilsson PM, Lindholm LH, Persson K, Wadstrom T (2000) Combined seropositivity for H. pylori and C. pneumoniae is associated with age, obesity and social factors. J Cardiovasc Risk 7:191–195
26. Crabtree JE, Farmery SM, Lindley IJD, Figura N, Peichl P, Tompkins DS (1994) CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol 47:945–950
27. Rasmi Y, Raeisi S, Seyyed Mohammadzad MH (2012) Association of inflammation and cytotoxin-associated gene A positive strains of Helicobacter pylori in cardiac syndrome x. Helicobacter 17:116–120
28. Perri F, Clemente R, Festa V, De Ambrosio CC, Quitadamo M, Fusillo M, Grossi E, Andriulli A (1999) Serum tumour necrosis factor-alpha is increased in patients with Helicobacter pylori infection and CagA antibodies. Ital J Gastroenterol Hepatol 31:290–294
29. Chimienti G, Russo F, Lamanuzzi BL, Nardulli M, Messa C, Di Leo A, Correale M, Pepe G (2003) Helicobacter pylori is associated with modified lipid profile: impact on Lipoprotein(a). Clin Biochem 36:359–365
30. Lopes-Virella MF (1993) Interactions between bacterial lipopolysaccharide and serum lipoproteins and their possible role in coronary heart disease. Eur Heart J 14:118–124
31. Manco M, Putignani L, Bottazzo GF (2010) Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. Endocr Rev 31:817–844
32. Oshima T, Ozono R, Yano Y, Oishi Y, Teragawa H, Higashi Y, Yoshizumi M, Masayuki Kambe M (2005) Association of Helicobacter pylori infection with systemic inflammation and endothelial dysfunction in healthy male subjects. JACC 45:1219–1222
33. Jin W, Sun G-S, Marchadier D, Octaviani E, Glick JM, Rader DJ (2003) Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase. Circ Res 92:644–650
34. Riwanto M, Landmesser U (2013) High-density lipoproteins and endothelial functions: mechanistic insights and alterations in cardiovascular disease. J Lipid Res [Epub ahead of print]
35. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995) Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95:2409–2415
36. Wellen KE, Hotamisligil GS (2005) Inflammation, stress, and diabetes. J Clin Invest 115:1111–1119
37. Ojetti V, Pellicano R, Fagoonee S, Migneco A, Berrutti M, Gasbarrini A (2010) Helicobacter pylori infection and diabetes. Minerva Med 101:115–119
38. Burghen GA, Murrell LR, Whitington GL, Klyce MK, Burstein S (1992) Acid peptic disease in children with type I diabetes mellitus: a complicating relationship. Am J Dis Child 146:718–722
39. Nweneka CV, Prentice AM (2011) Helicobacter pylori infection and circulating ghrelin levels: a systematic review. BMC Gastroenterol 11:7–25
40. Lane JA, Murray LJ, Harvey IM, Donovan JL, Nair P, Harvey RF (2011) Randomised clinical trial: Helicobacter pylori eradication is associated with a significantly increased body mass index in a placebo-controlled study. Aliment Pharmacol Ther 33:922–929
41. Vahdat K, Azizi F, Zandi K, Assadi M, Nabipour I (2012) Chronic inflammation is correlated with percentage of body fat independent of the burden of infection. Inflammation 35:1322–1329
42. Kebapcilar L, Sari I, Renkal AH, Alacacioglu A, Yuksel A, Ilhan E, Alkan B, Yuksel D, Kozaci DL, Gunay N (2009) The influence of Helicobacter pylori eradication on leptin, soluble CD40 ligand, oxidative stress and body composition in patients with peptic ulcer disease. Intern Med 48:2055–2059
43. Menchine MD, Arora S, Camargo CA, Ginde AA (2011) Prevalence of undiagnosed and suboptimally controlled diabetes by point-of-care HbA1C in unselected emergency department patients. Acad Emerg Med 18:326–329
44. Danesh J, Peto R (1998) Risk factors for coronary heart disease and infection with Helicobacter pylori: meta-analysis of 18 studies. BMJ 7138:1130–1132
45. Cho I, Blaser MJ, François F, Mathew JP, Ye XY, Goldberg JD, Bini EJ (2005) Helicobacter pylori and overweight status in the United States: data from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 162:79–84
46. Furuta T, Shirai N, Xiao F, Takashima M, Hanai H (2002) Effect of Helicobacter pylori infection and its eradication on nutrition. Aliment Pharmacol Ther 16:799–806
47. Azuma T, Suto H, Ito Y, Muramatsu A, Ohtani M, Dojo M, Yamazaki Y, Kuriyama M, Kato T (2002) Eradication of Helicobacter pylori infection induces an increase in body mass index. Aliment Pharmacol Ther 16:240–244
48. Kagawa M, Kerr D, Uchida H, Binns C (2009) Differences in the relationship between BMI and percentage body fat between Japanese and Australian-Caucasian young men. Br J Nutr 95:1002–1007