Crossreactive autoantibodies directed against cutaneous and joint antigens are present in psoriatic arthritis

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Dolcino, Marzia ^a   Lunardi, Claudio ^b   Ottria, Andrea ^c   Tinazzi, Elisa ^b   Patuzzo, Giuseppe ^b   Puccetti, Antonio ^a,c  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AUTOANTIBODY; CARRIER PROTEINS AND BINDING PROTEINS; DESMOCOLLIN; DESMOCOLLIN 3; FIBRILLIN; FIBRILLIN 3; IMMUNOGLOBULIN G; JOINT ANTIGEN; KERATIN; KERATIN 78; NEBULIN RELATED ANCHORING PROTEIN; PEPTIDE; SKIN ANTIGEN; THREONYLASPARAGINYLARGINYLARGINYLGLYCYLARGINYLGLYCYLSERYLPHENYLALANYLGLYCYLALANYLLEUCINE; TISSUE ANTIGEN; UNCLASSIFIED DRUG; AUTOANTIGEN; PEPTIDE LIBRARY;

ADULT; ANTIBODY AFFINITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; CYTOSKELETON; DESMOSOME; DISEASE ASSOCIATION; FEMALE; HUMAN; MALE; PROTEIN LOCALIZATION; PSORIATIC ARTHRITIS; RHEUMATOID ARTHRITIS; IMMUNOLOGY; ISOLATION AND PURIFICATION; JOINT; PEPTIDE LIBRARY; SKIN; WESTERN BLOTTING;

ARTHRITIS, PSORIATIC; AUTOANTIBODIES; AUTOANTIGENS; BLOTTING, WESTERN; HUMANS; IMMUNOGLOBULIN G; JOINTS; PEPTIDE LIBRARY; SKIN;

EID: 84918583382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115424     Document Type: Article

References (30)

1. Eder L, Gladman DD (2013) Psoriatic arthritis: phenotypic variance and nosology. Curr Rheumatol Rep 15: 316.
2. Stolwijk C, Boonen A, van Tubergen A, Reveille JD (2012) Epidemiology of spondyloarthritis. Rheum Dis Clin North Am 38: 441-476.
3. Rahman P, Elder JT (2005) Genetic epidemiology of psoriasis and psoriatic arthritis. Ann Rheum Dis 64 Suppl 2: ii37-39; discussion ii40-31.
4. Ritchlin CT (2005) Pathogenesis of psoriatic arthritis. Curr Opin Rheumatol 17: 406-412.
5. Tomfohrde J, Silverman A, Barnes R, Fernandez-Vina MA, Young M, et al. (1994) Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 264: 1141-1145.
6. Moll JM, Wright V (1973) Psoriatic arthritis. Semin Arthritis Rheum 3: 55-78.
7. Mease P (2013) Psoriatic arthritis and spondyloarthritis assessment and management update. Curr Opin Rheumatol 25: 287-296.
8. McGonagle DG, Helliwell P, Veale D (2012) Enthesitis in psoriatic disease. Dermatology 225: 100-109.
9. Villanova F, Di Meglio P, Nestle FO (2013) Biomarkers in psoriasis and psoriatic arthritis. Ann Rheum Dis 72 Suppl 2: ii104-110.
10. Ritchlin C (2012) Biomarker development in psoriatic arthritis. J Rheumatol Suppl 89: 57-60.
11. McGonagle D, Ash Z, Dickie L, McDermott M, Aydin SZ (2011) The early phase of psoriatic arthritis. Ann Rheum Dis 70 Suppl 1: i71-76.
12. Lunardi C, Bason C, Leandri M, Navone R, Lestani M, et al. (2002) Autoantibodies to inner ear and endothelial antigens in Cogan's syndrome. Lancet 360: 915-921.
13. Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, et al. (2006) In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med 3: e358.
14. Frulloni L, Lunardi C, Simone R, Dolcino M, Scattolini C, et al. (2009) Identification of a novel antibody associated with autoimmune pancreatitis. N Engl J Med 361: 2135-2142.
15. Lunardi C, Bason C, Navone R, Millo E, Damonte G, et al. (2000) Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells. Nat Med 6: 1183-1186.
16. Duarte GV, Faillace C, Freire de Carvalho J (2012) Psoriatic arthritis. Best Pract Res Clin Rheumatol 26: 147-156.
17. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, et al. (2010) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 62: 2569-2581.
18. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, et al. (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25: 1271-1277.
19. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, et al. (2002) Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American- European Consensus Group. Ann Rheum Dis 61: 554-558.
20. Rudwaleit M, Khan MA, Sieper J (2005) The challenge of diagnosis and classification in early ankylosing spondylitis: do we need new criteria? Arthritis Rheum 52: 1000-1008.
21. Raychaudhuri SK, Maverakis E, Raychaudhuri SP (2014) Diagnosis and classification of psoriasis. Autoimmun Rev 13: 490-495.
22. Luo G, Herrera AH, Horowits R (1999) Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks. Biochemistry 38: 6135-6143.
23. Luo G, Zhang JQ, Nguyen TP, Herrera AH, Paterson B, et al. (1997) Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle. Cell Motil Cytoskeleton 38: 75-90.
24. Wellings DA, Atherton E (1997) Standard Fmoc protocols. Methods Enzymol 289: 44-67.
25. Davis MR, Andersson R, Severin J, de Hoon M, Bertin N, et al. (2014) Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions. Mol Genet Metab 112: 73-83.
26. Saruta H, Ishii N, Teye K, Ono F, Ohyama B, et al. (2013) Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies. JAMA Dermatol 149: 1209-1213.
27. Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, et al. (2007) IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J Immunol 179: 7128-7136.
28. Lunardi C, Bason C, Dolcino M, Navone R, Simone R, et al. (2009) Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's disease. J Intern Med 265: 250-265.
29. Reynolds JM, Pappu BP, Peng J, Martinez GJ, Zhang Y, et al. (2010) Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. Immunity 32: 692-702.
30. He Z, Shotorbani SS, Jiao Z, Su Z, Tong J, et al. (2012) HMGB1 promotes the differentiation of Th17 via up-regulating TLR2 and IL-23 of CD14+ monocytes from patients with rheumatoid arthritis. Scand J Immunol 76: 483-490.