Do angiotensin type 2 receptors modulate haemodynamic effects of type 1 receptors in conscious newborn lambs?

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 15, Issue 4, 2014, Pages 450-457

  Vinturache, Angela E ^a   Smith, Francine G ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

ANG II; AT1R; AT2R; cardiovascular; haemodynamics; Neonate; physiology

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; UNCLASSIFIED DRUG; ZD 7155; ANGIOTENSIN 2 RECEPTOR ANTAGONIST;

ARTICLE; CONSCIOUSNESS LEVEL; CONTROLLED STUDY; FEMALE; GROUPS BY AGE; HEMODYNAMICS; KIDNEY BLOOD FLOW; LAMB; MALE; NEWBORN; NEWBORN PERIOD; NONHUMAN; PROTEIN FUNCTION; REGULATORY MECHANISM; VENOUS PRESSURE; ANIMAL; BLOOD PRESSURE; CONSCIOUSNESS; DIASTOLE; DRUG EFFECTS; KIDNEY; METABOLISM; SHEEP; SYSTOLE; VASCULAR RESISTANCE; VASCULARIZATION;

ANGIOTENSIN II TYPE 2 RECEPTOR BLOCKERS; ANIMALS; ANIMALS, NEWBORN; BLOOD PRESSURE; CONSCIOUSNESS; DIASTOLE; FEMALE; HEMODYNAMICS; KIDNEY; MALE; RECEPTOR, ANGIOTENSIN, TYPE 2; SHEEP; SYSTOLE; VASCULAR RESISTANCE;

EID: 84918534295     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320313506479     Document Type: Article

References (51)

1. Oliverio MI, Best CF, Kim H-S, et al. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. Am J Physiol. 1997 ; 272 (Renal Physiol 41). F515 - F520
2. Yoshida K, Perich R, Casley DJ, et al. Hypotensive effect of ZD7155, an angiotensin II receptor antagonist, parallels receptor occupancy in two-kidney, one-clip Goldblatt hypertensive rats. J Hypertens. 1998 ; 16 (5). 645-655
3. Kramer BK, Ritthaler T, Schweda F, et al. Effects of the angiotensin II type-1 receptor antagonist ZD7155 on angiotensin II-mediated regulation of renin secretion and renal renin gene expression, renal vasoconstriction, and blood pressure in rats. J Cardiovasc Pharmacol. 1998 ; 31 (5). 700-705
4. Cervenka L, Wang C-T, Navar LG. Effects of acute AT1 receptor blockade by candesartan on arterial pressure and renal function in rats. Am J Physiol. 1998 ; 274 (Renal Physiol 43). F940 - F945
5. Reid IA. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. Am J Physiol. 1992 ; 262: E763 - E778
6. Saxena PR. Interaction between the renin-angiotensin-aldosterone and sympathetic nervous systems. J Cardiovasc Pharmacol. 1992 ; 19: S80 - S88
7. Moore AF, Heiderstadt NT, Huang E, et al. Selective inhibition of the renal angiotensin type 2 receptor increases blood pressure in conscious rats. Hypertension. 2001 ; 37: 1285-1291
8. de Gasparo M. Angiotensin II and nitric oxide interaction. Heart Fail Rev. 2002 ; 7: 347-358
9. Siragy HM, Carey RM. Angiotensin type 2 receptors: potential importance in the regulation of blood pressure. Curr Opin Nephrol Hypertens. 2001 ; 10: 99-103
10. Trimper CE, Lumbers ER. The renin angiotensin system in foetal lambs. Pflügers Arch. 1972 ; 336: 1-10
11. Chiu AT, Carini DJ, Johnson AL, et al. Non-peptide angiotensin II receptor antagonists. II. Pharmacology of S-8308. Eur J Pharmacol. 1988 ; 157: 13-21
12. Pelayo JC, Eisner GM, Jose PA. The ontogeny of the renin-angiotensin system. Clin Perinatol. 1981 ; 8: 347-359
13. Broughton, Pipkin F, Kirkpatrick SML, Lumbers ER, et al. Renin and angiotensin-like levels in foetal, new-born and adult sheep. J Physiol. 1974 ; 241: 575-588
14. Velaphi SC, Despain K, Roy T, et al. The renin-angiotensin system in conscious newborn sheep: metabolic clearance rate and activity. Pediatr Res. 2007 ; 61: 681-686
15. Monument MJ, Smith FG. Age-dependent effects of captopril on the arterial baroreflex control of heart rate in conscious lambs. Exp Physiol. 2003 ; 88 (6). 761-768
16. O'Connor SJ, Fowden AL, Holdstock N, et al. Developmental changes in pulmonary and renal angiotensin-converting enzyme concentration in fetal and neonatal horses. Reprod Fertil Dev. 2002 ; 14: 413-417
17. Forhead AJ, Melvin R, Balouzet V, et al. Developmental changes in plasma angiotensin-converting enzyme concentration in fetal and neonatal lambs. Reprod Fertil Dev. 1998 ; 10: 393-398
18. Arens Y, Chapados RA, Cox BE, et al. Differential development of umbilical and systemic arteries: II. contractile proteins. Am J Physiol. 1998 ; 274: R1815 - R1823
19. Bagby SP, LeBard LS, Luo Z, et al. Angiotensin II type 1 and 2 receptors in conduit arteries of normal developing swine. Arterioscler Thromb Vasc Biol. 2002 ; 22: 1113-1121
20. Bensoussan M, Heudes D, Nahmias C, et al. Organ culture of rat kidney: a model for angiotensin receptor ontogenic studies. Kidney Int. 1995 ; 48 (5). 1635-1640
21. Bagby SP, LeBard LS, Luo Z, et al. ANG II AT1 and AT2 receptors in developing kidney of normal microswine. Am J Physiol Renal Physiol. 2002 ; 283: F755 - F764
22. Burrell JH, Hegarty BD, McMullen JR, et al. Effects of gestation on ovine fetal and maternal angiotensin receptor subtypes in the heart and major blood vessels. Exp Physiol. 2001 ; 86 (1). 71-82
23. Ciuffo GM, Viswanathan M, Seltzer AM, et al. Glomerular angiotensin II receptors subtypes during development of rat kidney. Am J Physiol. 1993 ; 265: F264 - F271
24. Gröne HJ, Simon M, Fuchs E. Autoradiographic characterization of angiotensin receptor subtypes in fetal and adult human kidney. Am J Physiol. 1992 ; 262 (31). F326 - F331
25. Kaiser JR, Cox BE, Roy TA, et al. Differential development of umbilical and systemic arteries. I. ANG II receptor subtype expression. Am J Physiol Regul Integr Comp Physiol. 1998 ; 274: R797 - R807
26. Millan MA, Jacobowitz DM, Aguilera G, et al. Differential distribution of AT1 and AT2 angiotensin II receptor subtypes in the rat brain during development. Proc Natl Acad Sci USA. 1991 ; 88: 11440-11444
27. Robillard JE, Schutte BC, Page WV, et al. Ontogenic changes and regulation of renal angiotensin II type 1 receptor gene expression during fetal and newborn life. Pediatr Res. 1994 ; 36 (6). 755-762
28. Wintour EM, Moritz K, Butkus A, et al. Ontogeny and regulation of the AT1 and AT2 receptors in the ovine fetal adrenal gland. Mol Cell Endocrinol. 1999 ; 157 (1-2). 161-170
29. Wintour EM, Alcorn D, Albiston A, et al. The renin-angiotensin system and the development of the kidney and adrenal in sheep. Clin Exp Pharmacol Physiol. 1998 ; 25: S97 - S100
30. Robillard JE, Page WV, Mathews MS, et al. Differential gene expression and regulation of renal angiotensin II receptor subtypes (AT1 and AT2) during fetal life in sheep. Pediatr Res. 1995 ; 38 (6). 896-904
31. Kintscher U, Unger T. Angiotensin II receptor expression: from maturation to pathogenesis. Am J Physiol Regul Integr Comp Physiol. 2003 ; 285: R26 - R27
32. Cox BE, Rosenfeld CR. Ontogeny of vascular angiotensin II receptor subtype expression in ovine development. Pediatr Res. 1999 ; 45 (3). 414-424
33. Qi W, Vinturache AE, Smith FG. Cardiovascular and renal effects of angiotensin II type 2 receptors (AT2R) during ontogeny. Curr Topics Pharmacol. 2011 ; 15: 1-13
34. Chappellaz ML, Smith FG. Dose dependent systemic and renal haemodynamic effects of angiotensin II in conscious lambs: Role of angiotensin AT1 and AT2 receptors. Exp Physiol. 2005 ; 90 (6). 837-845
35. Chappellaz ML, Smith FG. Systemic and renal hemodynamic effects of the AT1 receptor antagonist, ZD 7155, and the AT2 receptor antagonist, PD 123319, in conscious lambs. Pflugers Arch. 2007 ; 453 (4). 477-486
36. Wehlage SJ, Smith FG. Nitric oxide and angiotensin II regulate cardiovascular homeostasis and the arterial baroreflex control of heart rate in conscious lambs. J RAAS. 2012 ; 13 (1). 99-107
37. Jones ES, Vinh A, McCarthy CA, et al. AT2 receptors: functional relevance in cardiovascular disease. Pharmacol Ther. 2008 ; 120 (3). 292-316
38. Batenburg WW, Tom B, Schuijt MP, et al. Angiotensin II type 2 receptor-mediated vasodilation. Focus on bradykinin, NO and endothelium-derived hyperpolarizing factor(s). Vascul Pharmacol. 2005 ; 42 (3). 109-118
39. Sener A, Smith FG. Acetylcholine chloride and renal haemodynamics during postnatal maturation in conscious lambs. J Appl Physiol. 1999 ; 87 (4). 1296-1300
40. Smith FG, Abraham J. Renal and renin responses to furosemide in conscious lambs during postnatal maturation. Can J Physiol Pharmacol. 1995 ; 73 (1). 107-112
41. de Wildt SN, Smith FG. Effects of the angiotensin converting enzyme (ACE) inhibitor, captopril, on the cardiovascular, endocrine and renal responses to furosemide in conscious lambs. Can J Physiol Pharmacol. 1997 ; 75 (4). 263-270
42. Velaphi SC, Roy T, Despain K, et al. Differential responses to systemic and local angiotensin II infusions in conscious postnatal sheep. Pediatr Res. 2002 ; 52 (3). 333-341
43. Carey RM, Wang Z-Q, Siragy HM. Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function. Hypertension. 2000 ; 35: 155-173
44. Siragy HM, El-Kersh MA, de Gasparo M, et al. Differences in AT2-receptor stimulation between AT1-receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. J Hypertens. 2002 ; 20: 1157-1163
45. Carey RM. Cardiovascular and renal regulation by the angiotensin type 2 receptor: The AT2 receptor comes of age. Hypertension. 2005 ; 45 (5). 840-844
46. Shah MM, Tee JB, Meyer T, et al. The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects. Am J Physiol Renal Physiol. 2009 ; 297 (5). F1330 - F1341
47. Rosenfeld CR, Despain K, Word RA, et al. Differential sensitivity to angiotensin II and norepinephrine in human uterine arteries. J Clin Endocrinol Metab. 2012 ; 97 (1). 138-147
48. Siragy HM. AT1 and AT2 receptors in the kidney: Role in disease and treatment. Am J Kidney Dis. 2000 ; 36 (3). S4 - S9
49. Siragy HM. AT1 and AT2 receptor in the kidney: Role in health and disease. Semin Nephrol. 2004 ; 24 (2). 93-100
50. Siragy HM, Carey RM. The subtype-2 (AT2) angiotensin receptor regulates renal cyclic guanosine 3', 5'-monophosphate and AT1 receptor-mediated prostaglandin E2 production in conscious rats. J Clin Invest. 1996 ; 97 (8). 1978-1982
51. Ratliff B, Rodebaugh J, Sekulic M, et al. Nitric oxide synthase and renin-angiotensin gene expression and NOS function in the postnatal renal resistance vasculature. Pediatr Nephrol. 2009 ; 24 (2). 355-365