Optogenetic approaches to study stroke recovery

ACS Chemical Neuroscience

Volumn 5, Issue 12, 2014, Pages 1144-1145

  Cheng, Michelle Y ^a   Wang, Eric H ^a   Steinberg, Gary K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Channelrhodopsin; Neurotrophin; Optogenetics; Plasticity; Stroke recovery

Indexed keywords

BRAIN DEPTH STIMULATION; CEREBROVASCULAR ACCIDENT; CONVALESCENCE; HUMAN; MOLECULAR MECHANICS; MOTOR CORTEX; NERVE CELL PLASTICITY; NERVE CELL STIMULATION; NONHUMAN; OPTOGENETICS; SHORT SURVEY; ANIMAL; BRAIN; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; STROKE;

RHODOPSIN;

ANIMALS; BRAIN; HUMANS; NEURONAL PLASTICITY; OPTOGENETICS; PHOTIC STIMULATION; RECOVERY OF FUNCTION; RHODOPSIN; STROKE;

EID: 84918521865     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn500216f     Document Type: Short Survey

References (5)

1. Roger, V. L., Go, A. S., Lloyd-Jones, D. M., et al. (2012) Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 125 (1), e2-e220, DOI: 10.1161/CIR.0b013e31823ac046.
2. Murphy, T. H., and Corbett, D. (2009) Plasticity during stroke recovery: From synapse to behaviour. Nat. Rev. Neurosci. 10 (12), 861-872, DOI: 10.1038/nrn2735.
3. Fenno, L., Yizhar, O., and Deisseroth, K. (2011) The development and application of optogenetics. Annu. Rev. Neurosci. 34, 389-412, DOI: 10.1146/annurev-neuro-061010-113817.
4. Cheng, M. Y., Wang, E. H., Woodson, W. J., et al. (2014) Optogenetic neuronal stimulation promotes functional recovery after stroke. Proc. Natl. Acad. Sci. U.S.A., 1-6, DOI: 10.1073/pnas.1404109111.
5. Xerri, C., Zennou-Azogui, Y., Sadlaoud, K., and Sauvajon, D. (2014) Interplay between intra- and interhemispheric remodeling of neural networks as a substrate of functional recovery after stroke: Adaptive versus maladaptive reorganization. Neuroscience, DOI: 10.1016/j.neuroscience.2014.06.066.