Efficiency of gas transfer in venovenous extracorporeal membrane oxygenation: analysis of 317 cases with four different ECMO systems

Intensive Care Medicine

Volumn 40, Issue 12, 2014, Pages 1870-1877

  Lehle, Karla ^a   Philipp, Alois ^a   Hiller, Karl Anton ^a   Zeman, Florian ^a   Buchwald, Dirk ^b   Schmid, Christof ^a   Dornia, Christian ^a   Lunz, Dirk ^a   Müller, Thomas ^a   Lubnow, Matthias ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

CO2 removal; ECMO; Gas transfer; O2 transfer; PMP oxygenator

Indexed keywords

ADULT; ANALYTICAL PARAMETERS; ARTICLE; BLOOD FLOW VELOCITY; BLOOD GAS ANALYSIS; BLOOD GAS ANALYZER; CARBON DIOXIDE ELIMINATION CAPACITY; CARBON DIOXIDE TRANSPORT; DISEASE SEVERITY; EXTRACORPOREAL MEMBRANE OXYGENATION DEVICE; EXTRACORPOREAL OXYGENATION; FEMALE; GAS DIFFUSION; GAS EXCHANGE; GAS EXCHANGE SURFACE; GAS FLOW; HUMAN; HYPERCAPNIA; HYPOXEMIA; MAJOR CLINICAL STUDY; MALE; MEMBRANE OXYGENATOR; OXYGEN DIFFUSION; OXYGEN TRANSPORT; RESPIRATORY FAILURE; RETROSPECTIVE STUDY; VENOVENOUS EXTRACORPOREAL MEMBRANE OXYGENATION; AGED; ANOXIA; COMPARATIVE STUDY; COMPLICATION; DEVICES; EQUIPMENT DESIGN; GERMANY; HEMODYNAMICS; ITALY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RESPIRATORY INSUFFICIENCY; STATISTICS AND NUMERICAL DATA;

CARBON DIOXIDE; OXYGEN;

ADULT; AGED; ANOXIA; CARBON DIOXIDE; EQUIPMENT DESIGN; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; GERMANY; HEMODYNAMICS; HUMANS; HYPERCAPNIA; ITALY; MALE; MIDDLE AGED; OXYGEN; RESPIRATORY INSUFFICIENCY; RETROSPECTIVE STUDIES;

EID: 84918507534     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-014-3489-z     Document Type: Article

References (16)

1. MacLaren G, Combes A, Bartlett RH (2012) Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era. Intensive Care Med 38:210–220
2. Patroniti N, Zangrillo A, Pappalardo F, Peris A, Cianchi G, Braschi A, Iotti GA, Arcadipane A, Panarello G, Ranieri VM, Terragni P, Antonelli M, Gattinoni L, Oleari F, Pesenti A (2011) The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med 37:1447–1457
3. Karagiannidis C, Lubnow M, Philipp A, Riegger GA, Schmid C, Pfeifer M, Mueller T (2010) Autoregulation of ventilation with neurally adjusted ventilatory assist on extracorporeal lung support. Intensive Care Med 36:2038–2044
4. Khoshbin E, Roberts N, Harvey C, Machin D, Killer H, Peek GJ, Sosnowski AW, Firmin RK (2005) Poly-methyl pentene oxygenators have improved gas exchange capability and reduced transfusion requirements in adult extracorporeal membrane oxygenation. ASAIO J 51:281–287
5. Peek GJ, Killer HM, Reeves R, Sosnowski AW, Firmin RK (2002) Early experience with a polymethyl pentene oxygenator for adult extracorporeal life support. ASAIO J 48:480–482
6. Allen S, Holena D, McCunn M, Kohl B, Sarani B (2011) A review of the fundamental principles and evidence base in the use of extracorporeal membrane oxygenation (ECMO) in critically ill adult patients. J Intensive Care Med 26:13–26
7. Sidebotham D, McGeorge A, McGuinness S, Edwards M, Willcox T, Beca J (2010) Extracorporeal membrane oxygenation for treating severe cardiac and respiratory failure in adults: part 2-technical considerations. J Cardiothorac Vasc Anesth 24:164–172
8. Snyder TA, Eash HJ, Litwak KN, Frankowski BJ, Hattler BG, Federspiel WJ, Wagner WR (2006) Blood biocompatibility assessment of an intravenous gas exchange device. Artif Organs 30:657–664
9. Jegger D, Revelly JP, Horisberger J, Mallabiabarrena I, Seigneul I, Jachertz M, Von Segesser LK (2005) Ex vivo evaluation of a new extracorporeal lung assist device: novaLung membrane oxygenator. Int J Artif Organs 28:985–999
10. Park M, Costa EL, Maciel AT, Silva DP, Friedrich N, Barbosa EV, Hirota AS, Schettino G, Azevedo LC (2013) Determinants of oxygen and carbon dioxide transfer during extracorporeal membrane oxygenation in an experimental model of multiple organ dysfunction syndrome. PLoS ONE 8:e54954
11. Lehle K, Philipp A, Muller T, Schettler F, Bein T, Schmid C, Lubnow M (2013) Flow dynamics of different adult ECMO systems: a clinical evaluation. Artif Organs 38(5):391–398
12. Muller T, Bein T, Philipp A, Graf B, Schmid C, Riegger G (2013) Extracorporeal pulmonary support in severe pulmonary failure in adults: a treatment rediscovered. Dtsch Arztebl Int 110:159–166
13. Peek GJ, Firmin RK (1999) The inflammatory and coagulative response to prolonged extracorporeal membrane oxygenation. ASAIO J 45:250–263
14. Agati S, Ciccarello G, Fachile N, Scappatura RM, Grasso D, Salvo D, Undar A, Mignosa C (2006) DIDECMO: a new polymethylpentene oxygenator for pediatric extracorporeal membrane oxygenation. ASAIO J 52:509–512
15. Pieri M, Turla OG, Calabro MG, Ruggeri L, Agracheva N, Zangrillo A, Pappalardo F (2013) A new phosphorylcholine-coated polymethylpentene oxygenator for extracorporeal membrane oxygenation: a preliminary experience. Perfusion 28:132–137
16. De Somer F, Francois K, van Oeveren W, Poelaert J, De Wolf D, Ebels T, Van Nooten G (2000) Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. Eur J Cardiothorac Surg 18:602–606