Suprabasin as a novel tumor endothelial cell marker

Cancer Science

Volumn 105, Issue 12, 2014, Pages 1533-1540

  Alam, Mohammad T ^a   Nagao Kitamoto, Hiroko ^a   Ohga, Noritaka ^a   Akiyama, Kosuke ^a   Maishi, Nako ^a   Kawamoto, Taisuke ^a   Shinohara, Nobuo ^b   Taketomi, Akinobu ^b   Shindoh, Masanobu ^a   Hida, Yasuhiro ^b   Hida, Kyoko ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Suprabasin; Suprabasin signaling; Tumor endothelial cell marker; Tumor endothelial cells

Indexed keywords

DIFFERENTIATION ANTIGEN; SBSN PROTEIN, HUMAN; SUPRABASIN PROTEIN, MOUSE; TUMOR MARKER; TUMOR PROTEIN;

ANIMAL; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; METASTASIS; MOUSE; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTIGENS, DIFFERENTIATION; CELL LINE, TUMOR; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84917707094     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12549     Document Type: Article

References (31)

1. Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 2002; 29: 15-8.
2. Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 2007; 6: 273-86.
3. Welti J, Loges S, Dimmeler S, Carmeliet P. Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer. J Clin Invest 2013; 123: 3190-200.
4. Willett CG, Boucher Y, di Tomaso E et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004; 10: 145-7.
5. Ivy SP, Wick JY, Kaufman BM. An overview of small-molecule inhibitors of VEGFR signaling. Nat Rev Clin Oncol 2009; 6: 569-79.
6. Jain RK, Duda DG, Clark JW, Loeffler JS. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006; 3: 24-40.
7. McDonald DM, Baluk P. Significance of blood vessel leakiness in cancer. Cancer Res 2002; 62: 5381-5.
8. Morikawa S, Baluk P, Kaidoh T, Haskell A, Jain RK, McDonald DM. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol 2002; 160: 985-1000.
9. Jain RK. Molecular regulation of vessel maturation. Nat Med 2003; 9: 685-93.
10. St Croix B, Rago C, Velculescu V et al. Genes expressed in human tumor endothelium. Science 2000; 289: 1197-202.
11. Akiyama K, Ohga N, Hida Y et al. Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment. Am J Pathol 2012; 180: 1283-93.
12. Osawa T, Ohga N, Akiyama K et al. Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis. Br J Cancer 2013; 109: 2237-47.
13. Muraki C, Ohga N, Hida Y et al. Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. Int J Cancer 2012; 130: 59-70.
14. Maishi N, Ohga N, Hida Y et al. CXCR7: a novel tumor endothelial marker in renal cell carcinoma. Pathol Int 2012; 62: 309-17.
15. Osawa T, Ohga N, Hida Y et al. Prostacyclin receptor in tumor endothelial cells promotes angiogenesis in an autocrine manner. Cancer Sci 2012; 103: 1038-44.
16. Yamamoto K, Ohga N, Hida Y et al. Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells. Br J Cancer 2012; 106: 1214-23.
17. Matsui T, Hayashi-Kisumi F, Kinoshita Y et al. Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. Genomics 2004; 84: 384-97.
18. Park GT, Lim SE, Jang SI, Morasso MI. Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor. J Biol Chem 2002; 277: 45195-202.
19. Glazer CA, Smith IM, Ochs MF et al. Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC. PLoS ONE 2009; 4: e8189.
20. Formolo CA, Williams R, Gordish-Dressman H, MacDonald TJ, Lee NH, Hathout Y. Secretome signature of invasive glioblastoma multiforme. J Proteome Res 2011; 10: 3149-59.
21. Shao C, Tan M, Bishop JA et al. Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma. PLoS ONE 2012; 7: e48582.
22. Akino T, Hida K, Hida Y et al. Cytogenetic abnormalities of tumor-associated endothelial cells in human malignant tumors. Am J Pathol 2009; 175: 2657-67.
23. Ohga N, Hida K, Hida Y et al. Inhibitory effects of epigallocatechin-3 gallate, a polyphenol in green tea, on tumor-associated endothelial cells and endothelial progenitor cells. Cancer Sci 2009; 100: 1963-70.
24. Kondoh M, Ohga N, Akiyama K et al. Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. PLoS ONE 2013; 8: e80349.
25. Kawamoto T, Ohga N, Akiyama K et al. Tumor-derived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis. PLoS ONE 2012; 7: e34045.
26. Kurosu T, Ohga N, Hida Y et al. HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium. Br J Cancer 2011; 104: 819-29.
27. Matsuda K, Ohga N, Hida Y et al. Isolated tumor endothelial cells maintain specific character during long-term culture. Biochem Biophys Res Commun 2010; 394: 947-54.
28. Akiyama K, Ohga N, Maishi N et al. The F-prostaglandin receptor is a novel marker for tumor endothelial cells in renal cell carcinoma. Pathol Int 2013; 63: 37-44.
29. Bussolati B, Deambrosis I, Russo S, Deregibus MC, Camussi G. Altered angiogenesis and survival in human tumor-derived endothelial cells. FASEB J 2003; 17: 1159-61.
30. Hida K, Hida Y, Amin DN et al. Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res 2004; 64: 8249-55.
31. Ohga N, Ishikawa S, Maishi N et al. Heterogeneity of tumor endothelial cells: comparison between tumor endothelial cells isolated from high- and low-metastatic tumors. Am J Pathol 2012; 180: 1294-307.