메뉴 건너뛰기




Volumn 74, Issue 23, 2014, Pages 7060-7068

Molecular modulation of estrogen-induced apoptosis by synthetic progestins in hormone replacement therapy: An insight into the Women's Health Initiative Study

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ESTRADIOL; GLUCOCORTICOID RECEPTOR; MEDROXYPROGESTERONE ACETATE; MIFEPRISTONE; NORETHISTERONE ACETATE; ESTROGEN; ESTROGEN RECEPTOR; GLUCOCORTICOID; NORETHISTERONE; PROGESTERONE DERIVATIVE;

EID: 84917706481     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1784     Document Type: Article
Times cited : (40)

References (35)
  • 2
    • 0016826567 scopus 로고
    • Increased risk of endometrial carcinoma among users of conjugated estrogens
    • Ziel HK, Finkle WD. Increased risk of endometrial carcinoma among users of conjugated estrogens. N Engl J Med 1975;293:1167-70.
    • (1975) N Engl J Med , vol.293 , pp. 1167-1170
    • Ziel, H.K.1    Finkle, W.D.2
  • 3
    • 0001657785 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
    • The Writing Group for the PEPI Trial. Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA 1996;275:370-5.
    • (1996) JAMA , vol.275 , pp. 370-375
  • 4
    • 0029781305 scopus 로고    scopus 로고
    • Evidence for primary and secondary prevention of coronary artery disease in women taking oestrogen replacement therapy
    • Bush TL. Evidence for primary and secondary prevention of coronary artery disease in women taking oestrogen replacement therapy. Eur Heart J 1996;Suppl D:9-14.
    • (1996) Eur Heart J , pp. 9-14
    • Bush, T.L.1
  • 5
    • 0025910420 scopus 로고
    • Hormone replacement therapy prevents coronary artery disease in ovariectomized cholesterol-fed rabbits
    • Haarbo J, Hansen BF, Christiansen C. Hormone replacement therapy prevents coronary artery disease in ovariectomized cholesterol-fed rabbits. APMIS 1991;99:721-7.
    • (1991) APMIS , vol.99 , pp. 721-727
    • Haarbo, J.1    Hansen, B.F.2    Christiansen, C.3
  • 6
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results From the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-33.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    LaCroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6
  • 7
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial
    • Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 2004;291:1701-12.
    • (2004) JAMA , vol.291 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2    Assaf, A.R.3    Bassford, T.4    Beresford, S.A.5    Black, H.6
  • 8
    • 74049104166 scopus 로고    scopus 로고
    • Estrogen regulation of apoptosis: How can one hormone stimulate and inhibit?
    • Lewis-Wambi JS, Jordan VC. Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit? Breast Cancer Res 2009;11:206-18.
    • (2009) Breast Cancer Res , vol.11 , pp. 206-218
    • Lewis-Wambi, J.S.1    Jordan, V.C.2
  • 10
    • 46449134193 scopus 로고    scopus 로고
    • The 38th David A. Karnofsky Lecture: The paradoxical actions of estrogen in breast cancer-Survival or death?
    • Jordan VC. The 38th David A. Karnofsky Lecture: the paradoxical actions of estrogen in breast cancer-Survival or death? J Clin Oncol 2008;26:3078-82.
    • (2008) J Clin Oncol , vol.26 , pp. 3078-3082
    • Jordan, V.C.1
  • 11
    • 68949102467 scopus 로고    scopus 로고
    • Lower-dose vs. High-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study
    • Ellis MJ, Gao F, Dehdashti F, Jeffe DB, Marcom PK, Carey LA, et al. Lower-dose vs. high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: a phase 2 randomized study. JAMA 2009;302:774-80.
    • (2009) JAMA , vol.302 , pp. 774-780
    • Ellis, M.J.1    Gao, F.2    Dehdashti, F.3    Jeffe, D.B.4    Marcom, P.K.5    Carey, L.A.6
  • 12
    • 82755168809 scopus 로고    scopus 로고
    • Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time
    • Ariazi EA, Cunliffe HE, Lewis-Wambi JS, Slifker MJ, Willis AL, Ramos P, et al. Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time. Proc Natl Acad Sci U S A 2011;108:18879-86.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 18879-18886
    • Ariazi, E.A.1    Cunliffe, H.E.2    Lewis-Wambi, J.S.3    Slifker, M.J.4    Willis, A.L.5    Ramos, P.6
  • 13
    • 84880899869 scopus 로고    scopus 로고
    • c-Src modulates estrogen-induced stress and apoptosis in estrogendeprived breast cancer cells
    • Fan P, Griffith OL, Agboke FA, Anur P, Zou X, McDaniel RE, et al. c-Src modulates estrogen-induced stress and apoptosis in estrogendeprived breast cancer cells. Cancer Res 2013;73:4510-20.
    • (2013) Cancer Res , vol.73 , pp. 4510-4520
    • Fan, P.1    Griffith, O.L.2    Agboke, F.A.3    Anur, P.4    Zou, X.5    McDaniel, R.E.6
  • 14
    • 84891828889 scopus 로고    scopus 로고
    • Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells
    • Fan P, Agboke FA, McDaniel RE, Sweeney EE, Zou X, Creswell K, et al. Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells. Eur J Cancer 2014;50:457-68.
    • (2014) Eur J Cancer , vol.50 , pp. 457-468
    • Fan, P.1    Agboke, F.A.2    McDaniel, R.E.3    Sweeney, E.E.4    Zou, X.5    Creswell, K.6
  • 15
    • 84860474009 scopus 로고    scopus 로고
    • Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal hysterectomy: Extended follow-up of the Women's Health Initiative Randomised Trial
    • Anderson GL, Chlebowski RT, Aragaki AK, Kuller LH, Manson JE, Gass M, et al. Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal hysterectomy: extended follow-up of the Women's Health Initiative Randomised Trial. Lancet Oncol 2012;13:476-86.
    • (2012) Lancet Oncol , vol.13 , pp. 476-486
    • Anderson, G.L.1    Chlebowski, R.T.2    Aragaki, A.K.3    Kuller, L.H.4    Manson, J.E.5    Gass, M.6
  • 16
    • 0027304028 scopus 로고
    • Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk
    • Pike MC, Spicer DV, Dahmoush L, Press MF. Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiol Rev 1993;15:17-30.
    • (1993) Epidemiol Rev , vol.15 , pp. 17-30
    • Pike, M.C.1    Spicer, D.V.2    Dahmoush, L.3    Press, M.F.4
  • 17
  • 18
    • 84869489330 scopus 로고    scopus 로고
    • Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines
    • Fan P, McDaniel RM, Kim HR, Clagett D, Haddad B, Jordan VC. Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines. Eur J Cancer 2012;48:3488-98.
    • (2012) Eur J Cancer , vol.48 , pp. 3488-3498
    • Fan, P.1    McDaniel, R.M.2    Kim, H.R.3    Clagett, D.4    Haddad, B.5    Jordan, V.C.6
  • 19
    • 0037705388 scopus 로고    scopus 로고
    • Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL
    • Gascoyne DM, Kypta RM, Vivanco MD. Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL. J Biol Chem 2003;278:18022-9.
    • (2003) J Biol Chem , vol.278 , pp. 18022-18029
    • Gascoyne, D.M.1    Kypta, R.M.2    Vivanco, M.D.3
  • 21
    • 84888116498 scopus 로고    scopus 로고
    • Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer
    • Skor MN, Wonder EL, Kocherginsky M, Goyal A, Hall BA, Cai Y, et al. Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer. Clin Cancer Res 2013;19:6163-72.
    • (2013) Clin Cancer Res , vol.19 , pp. 6163-6172
    • Skor, M.N.1    Wonder, E.L.2    Kocherginsky, M.3    Goyal, A.4    Hall, B.A.5    Cai, Y.6
  • 22
    • 0026483203 scopus 로고
    • Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation
    • Jeng MH, Parker CJ, Jordan VC. Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation. Cancer Res 1992;52:6539-46.
    • (1992) Cancer Res , vol.52 , pp. 6539-6546
    • Jeng, M.H.1    Parker, C.J.2    Jordan, V.C.3
  • 23
    • 0027196251 scopus 로고
    • Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism
    • Catherino WH, Jordan VC. Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism. Br J Cancer 1993;67:945-52.
    • (1993) Br J Cancer , vol.67 , pp. 945-952
    • Catherino, W.H.1    Jordan, V.C.2
  • 24
    • 0018854496 scopus 로고
    • Estrogen, androgen, glucocorticoid, and progesterone receptors in progestin-induced regression of human breast cancer
    • Tuelings FA, van Gilse HA, Henkelman MS, Portengen H, Alexieva-Figusch J. Estrogen, androgen, glucocorticoid, and progesterone receptors in progestin-induced regression of human breast cancer. Cancer Res 1980;40:2557-61.
    • (1980) Cancer Res , vol.40 , pp. 2557-2561
    • Tuelings, F.A.1    Van Gilse, H.A.2    Henkelman, M.S.3    Portengen, H.4    Alexieva-Figusch, J.5
  • 25
    • 79956289710 scopus 로고    scopus 로고
    • Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception
    • Africander D, Verhoog N, Hapgood JP. Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 2011;76:636-52.
    • (2011) Steroids , vol.76 , pp. 636-652
    • Africander, D.1    Verhoog, N.2    Hapgood, J.P.3
  • 26
    • 84856233481 scopus 로고    scopus 로고
    • Glucocorticoid receptor activity discriminates between progesterone and medroxyprogesterone acetate effects in breast cells
    • Courtin A, Communal L, Vilasco M, Cimino D, Mourra N, de Bortoli M, et al. Glucocorticoid receptor activity discriminates between progesterone and medroxyprogesterone acetate effects in breast cells. Breast Cancer Res Treat 2012;131:49-63.
    • (2012) Breast Cancer Res Treat , vol.131 , pp. 49-63
    • Courtin, A.1    Communal, L.2    Vilasco, M.3    Cimino, D.4    Mourra, N.5    De Bortoli, M.6
  • 27
    • 84907297504 scopus 로고    scopus 로고
    • Breast cancer cell apoptosis with phytoestrogens is dependent on an estrogen-deprived state
    • Obiorah IE, Fan P, Jordan VC. Breast cancer cell apoptosis with phytoestrogens is dependent on an estrogen-deprived state. Cancer Prev Res 2014;7:939-49.
    • (2014) Cancer Prev Res , vol.7 , pp. 939-949
    • Obiorah, I.E.1    Fan, P.2    Jordan, V.C.3
  • 28
    • 0030910876 scopus 로고    scopus 로고
    • Transcriptional activities of estrogen and glucocorticoid receptors are functionally integrated at the AP-1 response element
    • Uht RM, Anderson CM, Webb P, Kushner PJ. Transcriptional activities of estrogen and glucocorticoid receptors are functionally integrated at the AP-1 response element. Endocrinology 1997;138:2900-8.
    • (1997) Endocrinology , vol.138 , pp. 2900-2908
    • Uht, R.M.1    Anderson, C.M.2    Webb, P.3    Kushner, P.J.4
  • 29
    • 84882600977 scopus 로고    scopus 로고
    • Reprogramming the chromatin landscape: Interplay of the estrogen and glucocorticoid receptors at the genomic level
    • Miranda TB, Voss TC, Sung MH, Baek S, John S, Hawkins M, et al. Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level. Cancer Res 2013;73:5130-9.
    • (2013) Cancer Res , vol.73 , pp. 5130-5139
    • Miranda, T.B.1    Voss, T.C.2    Sung, M.H.3    Baek, S.4    John, S.5    Hawkins, M.6
  • 30
    • 84882383911 scopus 로고    scopus 로고
    • Interaction of glucocorticoid receptor (GR) with estrogen receptor (ER) a and activator protein 1 (AP1) in dexamethasone-mediated interference of ERa activity
    • Karmakar S, Jin Y, Nagaich AK. Interaction of glucocorticoid receptor (GR) with estrogen receptor (ER) a and activator protein 1 (AP1) in dexamethasone-mediated interference of ERa activity. J Biol Chem 2013;288:24020-34.
    • (2013) J Biol Chem , vol.288 , pp. 24020-24034
    • Karmakar, S.1    Jin, Y.2    Nagaich, A.K.3
  • 31
    • 84984998149 scopus 로고    scopus 로고
    • Linking estrogen-induced apoptosis with decreases in mortality following long term adjuvant tamoxifen therapy
    • pii dju296
    • Jordan VC. Linking estrogen-induced apoptosis with decreases in mortality following long term adjuvant tamoxifen therapy. J Natl Cancer Inst 2014;106:pii dju296.
    • (2014) J Natl Cancer Inst , vol.106
    • Jordan, V.C.1
  • 32
    • 84917710188 scopus 로고    scopus 로고
    • Timing is key to avoid the bad and enhance the good of soy supplements
    • In press
    • Jordan VC. Timing is key to avoid the bad and enhance the good of soy supplements. JNCI. In press.
    • JNCI
    • Jordan, V.C.1
  • 33
    • 84876175066 scopus 로고    scopus 로고
    • Scientific rationale for postmenopause delay in the use of conjugated equine estrogens among postmenopausal women that causes reduction in breast cancer incidence and mortality
    • Obiorah I, Jordan VC. Scientific rationale for postmenopause delay in the use of conjugated equine estrogens among postmenopausal women that causes reduction in breast cancer incidence and mortality. Menopause 2013;20:372-82.
    • (2013) Menopause , vol.20 , pp. 372-382
    • Obiorah, I.1    Jordan, V.C.2
  • 34
    • 79951931750 scopus 로고    scopus 로고
    • Green J Million Women Study Collaborators. Breast cancer risk in relation to the interval between menopause and starting hormone therapy
    • Beral V, Reeves G, Bull D, Green J Million Women Study Collaborators. Breast cancer risk in relation to the interval between menopause and starting hormone therapy. J Natl Cancer Inst 2011;103:296-305.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 296-305
    • Beral, V.1    Reeves, G.2    Bull, D.3
  • 35
    • 84914107396 scopus 로고    scopus 로고
    • A(nother) scientific strategy to prevent breast cancer in postmenopausal women by enhancing estrogen-induced apoptosis?
    • Jordan VC. A(nother) scientific strategy to prevent breast cancer in postmenopausal women by enhancing estrogen-induced apoptosis? Menopause 2014;21:1160-4.
    • (2014) Menopause , vol.21 , pp. 1160-1164
    • Jordan, V.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.