A novel model of mild traumatic brain injury for juvenile rats

Journal of Visualized Experiments

Volumn , Issue 94, 2014, Pages

  Mychasiuk, Richelle ^a   Farran, Allyson ^a   Angoa Perez, Mariana ^b   Briggs, Denise ^b   Kuhn, Donald ^b   Esser, Michael J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Childhood; Concussion; Issue 94; Neuroscience; Repetitive brain injury; Rodent; Translational research

Indexed keywords

EID: 84917693028     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/51820     Document Type: Article

References (10)

1. DeWitt, D., Perez-Polo, R., Hulsebosch, C., Dash, P., Robertson, C. Challenges in the development of rodent models of mild traumatic brain injury. Journal of Neurotrauma. 30, 688-701 (2013).
2. Xiong, Y., Mahmood, A., Chopp, M. Animal models of traumatic brain injury. Nature Reviews Neuroscience. 14, 128-142 (2013).
3. Zhang, Z., Lerner, S., Kobiessy, F., Hayes, R., Wang, K. Systems biology and the anostic approach to drug discovery and development to treat traumatic brain injury. Systems Biology in Drug Discovery and Development: Methods and Protocols, Methods in Molecular Biology. Yan, Q. Springer Science Forthcoming.
4. Viano, D., Casson, I., Pellmen, E. Concussion in profession football: Biomechanics of the struck player-Part 14. Neurosurgery. 61, 313-327 (2007).
5. Marmarou, A., et al. A new model of diffuse brain injury in rats: Part 1-Pathophysiology and biomechanics. Journal of Neurosurgery. 80, 291-300 (1994).
6. Mychasiuk, R., Farran, A., Esser, M. J. Assessment of an experimental rodent model of pediatric mild traumatic brain injury. Journal of Neurotrauma. 31, (8), (2014).
7. Kane, M., et al. A mouse model of human repetitive mild traumatic brain injury. Journal of Neuroscience Methods. 203, 41-49 (2012).
8. Schallert, T., Woodlee, M., Fleming, S. Disentangling multiple types of recovery from brain injury. Pharmacology of Cerebral Ischemia. Krieglstein, J., Klumpp, S. Medpharm Scientific Publishers Stuttgart (2002).
9. Mychasiuk, R., Hehar, H., Farran, A., Esser, M. J. Mean Girls: Sex differences in the effects of mild traumatic brain injury on the social dynamics of juvenile rat play behaviour. Behavioural Brain Research. 259, (2014).
10. Centers for Disease Control and Prevention. Report to congress on mild traumatic brain injury in the United States: Steps to prevent a serious public health problem. 1-47 Centers for Disease Control and Prevention Atlanta, GA (2003).