Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue

Oncotarget

Volumn 5, Issue 22, 2014, Pages 11017-11028

  David, Kerstin A ^a   Unger, Florian T ^a   Uhlig, Philipp ^a   Juhl, Hartmut ^a   Moore, Helen M ^b   Compton, Carolyn ^c   Nashan, Björn ^d   Dörner, Arnulf ^e   de Weerth, Andreas ^e   Zornig, Carsten ^f  

^a Indivumed GmbH   (Germany)

^b NATIONAL CANCER INSTITUTE   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e Clinic for General and Visceral Surgery and Clinic for Gastroenterology Agaplesion Diakonieklinikum Hamburg   (Germany)

^f ISRAELITISCHES KRANKENHAUS   (Germany)

Author keywords

Biospecimen; Drug development; EGFR pathway; Phosphoproteins; Predictive biomarker; Tissue quality

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; EGFR PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; CANCER SURGERY; CANCER TISSUE; CLINICAL ARTICLE; COLD ISCHEMIA; COLON RESECTION; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; ISCHEMIA; LIVER METASTASIS; LIVER RESECTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE FIXATION; BIOSYNTHESIS; COLORECTAL NEOPLASMS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LABORATORY DIAGNOSIS; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; PROCEDURES; PROGNOSIS; SECONDARY;

BIOMARKERS, TUMOR; COLORECTAL NEOPLASMS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SPECIMEN HANDLING;

EID: 84917690901     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2669     Document Type: Article

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