Dapoxetine for premature ejaculation: An updated meta-analysis of randomized controlled trials

Clinical Therapeutics

Volumn 36, Issue 12, 2014, Pages 2003-2014

  Li, Jinhong ^a   Yuan, Haichao ^a   Bai, Yunjin ^a   Pu, Chunxiao ^a   Tang, Yin ^a   Dong, Qiang ^a   Wei, Qiang ^a   Han, Ping ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

efficacy; meta analysis; premature ejaculation; safety; words dapoxetine

Indexed keywords

DAPOXETINE; BENZYLAMINE DERIVATIVE; NAPHTHALENE DERIVATIVE; SEROTONIN UPTAKE INHIBITOR;

ARTICLE; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; FAINTNESS; HEADACHE; HUMAN; INSOMNIA; MALE; META ANALYSIS; NAUSEA; PATIENT ATTITUDE; PREMATURE EJACULATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK FACTOR; SEXUAL INTERCOURSE; SEXUAL SATISFACTION; SOMNOLENCE; SYSTEMATIC REVIEW; WITHDRAWAL SYNDROME; CHEMICALLY INDUCED; DOUBLE BLIND PROCEDURE; TREATMENT OUTCOME;

BENZYLAMINES; DIARRHEA; DOUBLE-BLIND METHOD; HEADACHE; HUMANS; MALE; NAPHTHALENES; NAUSEA; PREMATURE EJACULATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEROTONIN UPTAKE INHIBITORS; TREATMENT OUTCOME;

EID: 84916894404     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2014.09.011     Document Type: Article

References (25)

1. C.G. McMahon, S. Althof, and M.D. Waldinger An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation BJU Int 102 2008 338 350
2. E.S. Byers, and G. Grenier Premature or rapid ejaculation: heterosexual couples' perceptions of men's ejaculatory behavior Arch Sex Behav 32 2003 261 270
3. D.L. Rowland, M.A. Perelman, and S.E. Althof Self-reported premature ejaculation and aspects of sexual functioning and satisfaction J Sex Med 1 2004 225 232
4. T. Symonds, D. Roblin, K. Hart, and S. Althof How does premature ejaculation impact a man's life? J Sex Marital Ther 29 2003 361 370
5. S.E. Althof, C.H. Abdo, and J. Dean International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation J Sex Med 7 2010 2947 2969
6. H. Porst, F. Montorsi, and R.C. Rosen The premature ejaculation prevalence and attitude (PEPA) survey: prevalence, comorbidities, and professional help-seeking Eur Urol 51 2007 816 823
7. C. Pu, L. Yang, and L. Liu Topical anesthetic agents for premature ejaculation: a systematic review and meta-analysis Urology 81 2013 799 804
8. S.M. Hoy, and L.J. Scott Dapoxetine: in premature ejaculation Drug 70 2010 1433 1443
9. J. Li, Q. Shi, and Y. Bai Efficacy and safety of muscarinic anatonists as add-on therapy for male lower urinary tract symptoms Sci Rep 4 2014 3948
10. D. Moher, B. Pham, and A. Jones Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet 352 1998 609 613
11. Higgins JPT, Green S. Cochrane Handbook For Systematic Review Of Interventions 5.1.0 updated March 2011. The Cochrane Collaboration, 2011. www.cochrane-handbook.org. Accessed November 26, 2014.
12. J. Pryor, S.E. Althof, and C. Steidle Efficacy and tolerability of dapoxetine in the treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials Lancet 368 2006 929 937
13. M.R. Safarinejad Comparison of dapoxetine versus paroxetine in patients with premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study Clin Neuropharmacol 29 2006 243 252
14. M.R. Safarinejad Safety and efficacy of dapoxetine in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study Neuropsychopharmacology 33 2008 1259 1265
15. J. Buvat, F. Tesfaye, and M. Rothman Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase 3 trial in 22 countries Eur Urol 55 2009 957 968
16. J.M. Kaufman, R.C. Rosen, and R.V. Mudumbi Treatment benefit of dapoxetine for premature ejaculation: results from a placebo-controlled phase III trial BJU Int 103 2009 651 658
17. C. McMahon, S.W. Kim, and N.C. Park Treatment of premature ejaculation in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetine J Sex Med 7 2010 256 268
18. C.G. McMahon Pharmacological treatment of ejaculatory disorders J Sex Med Suppl 1 2004 19 21
19. P.J. Gengo, F. Giuliano, and K. Mckenna Monoaminergic transporter binding and inhibition profile of dapoxetine, a medication for the treatment of premature ejaculation J Urol 173 2005 239 244
20. B. Feret Dapoxetine: A novel, fast-acting serotonin reuptake inhibitor Formulary 40 2005 227 230
21. N.B. Modi, M.J. Dresser, and M. Simon Single- and multiple-dose pharmacokinetics of dapoxetine hydrochloride, a novel agent for the treatment of premature ejaculation J Clin Pharmacol 46 2006 301 309
22. Y.B. Wang, Y. Mao, and Q. Wei Dapoxetine in treatment of premature ejaculation: a systematic review Beijing Da Xue Xue Bao 42 2010 425 432
23. Y.H. Luo, Q. Hou, and S.B. Zheng Meta-analysis of dapoxetine on demand in the treatment of premature ejaculation Zhonghua Nan Ke Xue 18 2012 930 935
24. E. Wespes, I. Eardley, and F. Giuliano Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation European Association of Urology Update March 2013 http://www.uroweb.org.guidelines/online-guidelines/. Accessed November 26, 2014
25. C.G. McMahon, F. Giuliano, and J. Dean Efficacy and safety of dapoxetine in men with premature ejaculation and concomitant erectile dysfunction treated with a phosphodiesterase type 5 inhibitor: randomized, placebo-controlled, phase III study J Sex Med 10 2013 2312 2325