Does the thyroid-stimulating hormone measured concurrently with first trimester biochemical screening tests predict adverse pregnancy outcomes occurring after 20 weeks gestation?

Journal of Clinical Endocrinology and Metabolism

Volumn 99, Issue 12, 2014, Pages E2668-E2672

  Ong, Gregory S Y ^a   Hadlow, Narelle C ^b   Brown, Suzanne J ^a   Lim, Ee Mun ^a,b   Walsh, John P ^a,c  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^b PATHWEST LABORATORY MEDICINE   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; LIOTHYRONINE; PREGNANCY ASSOCIATED PLASMA PROTEIN A; THYROID ANTIBODY; THYROTROPIN; THYROXINE; CHORIONIC GONADOTROPIN; THYROID HORMONE;

ADULT; ARTICLE; AUSTRALIA; BIRTH DEFECT; CHROMOSOME ABERRATION; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FETUS; FETUS OUTCOME; FIRST TRIMESTER PREGNANCY; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; NEWBORN; NEWBORN DEATH; PLACENTA PREVIA; PREDICTION; PREECLAMPSIA; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PREMATURE LABOR; SCREENING TEST; SMALL FOR DATE INFANT; SOLUTIO PLACENTAE; STILLBIRTH; THYROID FUNCTION TEST; BLOOD; PREDICTIVE VALUE; PREGNANCY; PREGNANCY COMPLICATIONS; SECOND TRIMESTER PREGNANCY;

ADULT; CHORIONIC GONADOTROPIN; COHORT STUDIES; FEMALE; HUMANS; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; THYROID FUNCTION TESTS; THYROID HORMONES; THYROTROPIN;

EID: 84916629517     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-1918     Document Type: Article

References (24)

1. Laurberg P, Andersen SL, Pedersen IB, Andersen S, Carle A. Screening for overt thyroid disease in early pregnancy may be preferable to searching for small aberrations in thyroid function tests. Clin Endocrinol. 2013;79:297-304.
2. Negro R, Schwartz A, Gismondi R, Tinelli A, Mangieri T, Stagnaro-Green A. Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy. J Clin Endocrinol Metab. 2010;95:1699-1707.
3. Lazarus JH, Bestwick JP, Channon S, et al. Antenatal thyroid screening and childhood cognitive function. NEngl JMed. 2012;366:493-501.
4. De Groot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97:2543-2565.
5. American Thyroid Association Taskforce on Thyroid Disease During Pregnancy and Postpartum, Stagnaro-Green A, Abalovich M, Alexander E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid. 2011;21:1081-1125.
6. Su PY, Huang K, Hao JH, et al. Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China. J Clin Endocrinol Metab. 2011;96:3234-3241.
7. Cleary-Goldman J, Malone FD, Lambert-Messerlian G, et al. Maternal thyroid hypofunction and pregnancy outcome. Obstet Gynecol. 2008;112:85-92.
8. Casey BM, Dashe JS, Wells CE, et al. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol. 2005;105:239-245.
9. Schneuer FJ, Nassar N, Tasevski V, Morris JM, Roberts CL. Association and predictive accuracy of high TSH serum levels in first trimester and adverse pregnancy outcomes. J Clin Endocrinol Metab. 2012;97:3115-3122.
10. Karakosta P, Alegakis D, Georgiou V, et al. Thyroid dysfunction and autoantibodies in early pregnancy are associated with increased risk of gestational diabetes and adverse birth outcomes. J Clin Endocrinol Metab. 2012;97:4464-4472.
11. Männistö T, Vääräsmäki M, Pouta A, et al. Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study. J Clin Endocrinol Metab. 2009;94:772-779.
12. Barrett SL, Bower C, Hadlow NC. Use of the combined first-trimester screen result and low PAPP-A to predict risk of adverse fetal outcomes. Prenat Diagn. 2008;28:28-35.
13. Gilbert RM, Hadlow NC, Walsh JP, et al. Assessment of thyroid function during pregnancy: first-trimester (weeks 9-13) reference intervals derived from Western Australian women. Med J Aust. 2008;189:250-253.
14. Le M, Tran B. Perinatal Statistics in Western Australia 2008: Twenty-sixth Annual Report of the Western Australian Midwives' Notification System. http://www.health.wa.gov.au/publications/documents/perinatal/PerinatalStatisticsWA2008.pdf Government of Western Australia, Department of Health. 2008. Accessed March 29, 2014.
15. Bower C, Rudy E, Callaghan A, Quick J. 2010 Report of the Birth Defects Registry of Western Australia 1980-2009. http://www.kemh.health.wa.gov.au/services/register-developmental-anomalies/documents/2010-Annual-Report.pdf King Edward Memorial Hospital. 2010. Accessed March 29, 2014.
16. Roberts CL, Lancaster PA. Australian national birthweight percentiles by gestational age. Med J Aust. 1999;170:114-118.
17. Negro R, Schwartz A, Gismondi R, Tinelli A, Mangieri T, Stagnaro-Green A. Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy. J Clin Endocrinol Metab. 2010;95:E44-E48.
18. Benhadi N, Wiersinga WM, Reitsma JB, Vrijkotte TG, Bonsel GJ. Higher maternalTSHlevels in pregnancy are associated with increased risk for miscarriage, fetal or neonatal death. Eur J Endocrinol. 2009;160:985-991.
19. Sahu MT, Das V, Mittal S, Agarwal A, Sahu M. Overt and subclinical thyroid dysfunction among Indian pregnant women and its effect on maternal and fetal outcome. Arch Gynecol Obstet. 2010;281:215-220.
20. Leung AS, Millar LK, Koonings PP, Montoro M, Mestman JH. Perinatal Outcome in Hypothyroid Pregnancies. Obstet Gynecol. 1993;81:349-353.
21. Abalovich M, Gutierrez S, Alcaraz G, Maccallini G, Garcia A, Levalle O. Overt and subclinical hypothyroidism complicating pregnancy. Thyroid. 2002;12:63-68.
22. Allan WC, Haddow JE, Palomaki GE, et al. Maternal thyroid deficiency and pregnancy complications: implications for population screening. J Med Screen. 2000;7:127-130.
23. Männistö T, Mendola P, Grewal J, Xie Y, Chen Z, Laughon SK. Thyroid Diseases and Adverse Pregnancy Outcomes in a Contemporary US Cohort. J Clin Endocrinol Metab. 2013;98:2725-2733.
24. Hirsch D, Levy S, Nadler V, Kopel V, Shainberg B, Toledano Y. Pregnancy outcomes in women with severe hypothyroidism. Eur J Endocrinol. 2013;169:313-320.