-
1
-
-
84885188024
-
New clinical, pathological and molecular prognostic models and calculators in patients with locally diagnosed anaplastic oligodendroglioma or oligoastrocytoma. A prognostic factor analysis of European Organisation for Research and Treatment of Cancer Brain Tumour Group Study 26951
-
Gorlia T, Delattre JY, Brandes AA et al (2013) New clinical, pathological and molecular prognostic models and calculators in patients with locally diagnosed anaplastic oligodendroglioma or oligoastrocytoma. A prognostic factor analysis of European Organisation for Research and Treatment of Cancer Brain Tumour Group Study 26951. Eur J Cancer 49:3477–3485
-
(2013)
Eur J Cancer
, vol.49
, pp. 3477-3485
-
-
Gorlia, T.1
Delattre, J.Y.2
Brandes, A.A.3
-
2
-
-
0034636186
-
Long-term outcome of low-grade oligodendroglioma and mixed glioma
-
Olson JD, Riedel E, DeAngelis LM (2000) Long-term outcome of low-grade oligodendroglioma and mixed glioma. Neurology 54:1442–1448
-
(2000)
Neurology
, vol.54
, pp. 1442-1448
-
-
Olson, J.D.1
Riedel, E.2
Deangelis, L.M.3
-
3
-
-
38949200071
-
Seizure characteristics and control following resection in 332 patients with low-grade gliomas
-
Chang EF, Potts MB, Keles GE et al (2008) Seizure characteristics and control following resection in 332 patients with low-grade gliomas. J Neurosurg 108:227–235
-
(2008)
J Neurosurg
, vol.108
, pp. 227-235
-
-
Chang, E.F.1
Potts, M.B.2
Keles, G.E.3
-
4
-
-
84904902698
-
European association for neuro-oncology (EANO) task force on malignant gliomaEANO guideline on the diagnosis and treatment of malignant glioma
-
Weller M, van den Bent M, Hopkins K, Tonn JC, Stupp R, Falini A, Cohen-Jonathan-Moyal E, Frappaz D, Henriksson R, Balana C, Chinot O, Ram Z, Reifenberger G, Soffietti R, Wick W (2014) European association for neuro-oncology (EANO) task force on malignant gliomaEANO guideline on the diagnosis and treatment of malignant glioma. Lancet Oncol 15(9):e395–403
-
(2014)
Lancet Oncol
, vol.15
, Issue.9
, pp. e395-e403
-
-
Weller, M.1
Van Den Bent, M.2
Hopkins, K.3
Tonn, J.C.4
Stupp, R.5
Falini, A.6
Cohen-Jonathan-Moyal, E.7
Frappaz, D.8
Henriksson, R.9
Balana, C.10
Chinot, O.11
Ram, Z.12
Reifenberger, G.13
Soffietti, R.14
Wick, W.15
-
5
-
-
0035933187
-
Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients
-
Surma-aho O, Niemelä M, Vilkki J et al (2001) Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients. Neurology 56:1285–1290
-
(2001)
Neurology
, vol.56
, pp. 1285-1290
-
-
Surma-Aho, O.1
Niemelä, M.2
Vilkki, J.3
-
6
-
-
0028200573
-
Cognitive functions and quality of life in patients with low-grade gliomas: The impact of radiotherapy
-
Taphoorn MJ, Schiphorst AK, Snoek FJ et al (1994) Cognitive functions and quality of life in patients with low-grade gliomas: the impact of radiotherapy. Ann Neurol 36:48–54
-
(1994)
Ann Neurol
, vol.36
, pp. 48-54
-
-
Taphoorn, M.J.1
Schiphorst, A.K.2
Snoek, F.J.3
-
7
-
-
0037010410
-
Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: A comparative study
-
Klein M, Heimans JJ, Aaronson NK et al (2002) Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study. Lancet 360:1361–1368
-
(2002)
Lancet
, vol.360
, pp. 1361-1368
-
-
Klein, M.1
Heimans, J.J.2
Aaronson, N.K.3
-
8
-
-
27144491350
-
North Central Cancer Treatment Group. Cognitive function after radiotherapy for supratentorial low-grade glioma: A North Central Cancer Treatment Group prospective study
-
Laack NN, Brown PD, Ivnik RJ et al (2005) North Central Cancer Treatment Group. Cognitive function after radiotherapy for supratentorial low-grade glioma: a North Central Cancer Treatment Group prospective study. Int J Radiat Oncol Biol Phys 63:1175–1183
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 1175-1183
-
-
Laack, N.N.1
Brown, P.D.2
Ivnik, R.J.3
-
9
-
-
68249131500
-
Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: Long-term follow-up
-
Douw L, Klein M, Fagel SS et al (2009) Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up. Lancet Neurol 8:810–818
-
(2009)
Lancet Neurol
, vol.8
, pp. 810-818
-
-
Douw, L.1
Klein, M.2
Fagel, S.S.3
-
10
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for patients with newly diagnosed glioblastoma
-
Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for patients with newly diagnosed glioblastoma. N Engl J Med 352:987–996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
11
-
-
84910149887
-
Temozolomide chemotherapy vs. Radiotherapy in molecularly characterized (1p loss) low-grade glioma. A randomized phase III Intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC study #22033-26033)
-
suppl; abstr 2007
-
Baumert B, Mason WP, Ryan G et al (2013) Temozolomide chemotherapy vs. radiotherapy in molecularly characterized (1p loss) low-grade glioma. A randomized phase III Intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC study #22033-26033). J Clin Oncol 31, suppl; abstr 2007
-
(2013)
J Clin Oncol 31
-
-
Baumert, B.1
Mason, W.P.2
Ryan, G.3
-
12
-
-
73349134695
-
NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide
-
Wick W, Hartmann C, Engel C et al (2009) NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide. J Clin Oncol 27:5874–5880
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
13
-
-
0032855728
-
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse
-
for the Temodal Brain Tumor Group
-
Yung WKA, Prados MD, Yaga-Tur R et al (1999) for the Temodal Brain Tumor Group. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. J Clin Oncol 17, 2762–2771
-
(1999)
J Clin Oncol
, vol.17
, pp. 2762-2771
-
-
Yung, W.1
Prados, M.D.2
Yaga-Tur, R.3
-
14
-
-
0033897173
-
A phase II study of temozolomide vs. Procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung WKA, Albright RE, Olson J et al (2000) A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 83:588–593
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.1
Albright, R.E.2
Olson, J.3
-
15
-
-
0023930146
-
Successful chemotherapy for recurrent malignant oligodendroglioma
-
Cairncross JG, Macdonald DR (1988) Successful chemotherapy for recurrent malignant oligodendroglioma. Ann Neurol 23(4):360–364
-
(1988)
Ann Neurol
, vol.23
, Issue.4
, pp. 360-364
-
-
Cairncross, J.G.1
Macdonald, D.R.2
-
16
-
-
0018859770
-
Modified procarbazine, CCNU, and vincristine (PCV 3) combination chemotherapy in the treatment of malignant brain tumors
-
Levin VA, Edwards MS, Wright DC, Seager ML, Schimberg TP, Townsend JJ, Wilson CB (1980) Modified procarbazine, CCNU, and vincristine (PCV 3) combination chemotherapy in the treatment of malignant brain tumors. Cancer Treat Rep 64(2–3):237–244
-
(1980)
Cancer Treat Rep
, vol.64
, Issue.23
, pp. 237-244
-
-
Levin, V.A.1
Edwards, M.S.2
Wright, D.C.3
Seager, M.L.4
Schimberg, T.P.5
Townsend, J.J.6
Wilson, C.B.7
-
17
-
-
33745532038
-
Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: A randomized European Organisation for Research and Treatment of Cancer
-
Van den Bent MJ, Carpentier AF, Brandes AA et al (2006) Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer. J Clin Oncol 24:2715–2722
-
(2006)
J Clin Oncol
, vol.24
, pp. 2715-2722
-
-
Van Den Bent, M.J.1
Carpentier, A.F.2
Brandes, A.A.3
-
18
-
-
33745575716
-
Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402
-
Cairncross G, Berkey B, Shaw E et al (2006) Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402. J Clin Oncol 24:2707–2714
-
(2006)
J Clin Oncol
, vol.24
, pp. 2707-2714
-
-
Cairncross, G.1
Berkey, B.2
Shaw, E.3
-
19
-
-
84863091424
-
Chemotherapy versus radiotherapy for malignant astrocytoma in the elderly
-
Wick W, Platten M, Meisner C et al (2012) Chemotherapy versus radiotherapy for malignant astrocytoma in the elderly. Lancet Oncol. 13(7):707–715
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. 707-715
-
-
Wick, W.1
Platten, M.2
Meisner, C.3
-
20
-
-
34548213721
-
Efficacy and tolerability of temozolomide in an one week on/one week off regimen in patients with recurrent glioma
-
Wick A et al (2007) Efficacy and tolerability of temozolomide in an one week on/one week off regimen in patients with recurrent glioma. J Clin Oncol 25:3357–3361
-
(2007)
J Clin Oncol
, vol.25
, pp. 3357-3361
-
-
Wick, A.1
-
21
-
-
77951648272
-
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study
-
Perry JR et al (2010) Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study. J Clin Oncol 28:2051–2057
-
(2010)
J Clin Oncol
, vol.28
, pp. 2051-2057
-
-
Perry, J.R.1
-
22
-
-
80052254518
-
RTOG 0525: A randomized phase III trial comparing standard adjuvant temozolomide with a dose-dense schedule in newly diagnosed glioblastoma
-
Gilbert M, Mehta M, Aldape K et al (2011) RTOG 0525: A randomized phase III trial comparing standard adjuvant temozolomide with a dose-dense schedule in newly diagnosed glioblastoma. J Clin Oncol 29:2006
-
(2011)
J Clin Oncol
, vol.29
, pp. 2006
-
-
Gilbert, M.1
Mehta, M.2
Aldape, K.3
-
23
-
-
84916614617
-
MGMT
-
Tabatabai G, Wick W, Steinbach JP, Wick A, Schnell O, et al. MGMT promoter methylation as a prognostic biomarker for benefit from dose-intensified temozolomide rechallenge in progressive glioblastoma: First results from the randomized phase II DIRECTOR trial. J Clin Oncol Suppl Abstract 2015 (2014)
-
(2014)
J Clin Oncol Suppl Abstract 2015
-
-
Tabatabai, G.1
Wick, W.2
Steinbach, J.P.3
Wick, A.O.4
-
25
-
-
84888229904
-
IDH1 mutations determine the prognostic versus predictive value of MGMT promoter methylation in malignant gliomas
-
Wick W, Meisner C, Hentschel B et al (2013) IDH1 mutations determine the prognostic versus predictive value of MGMT promoter methylation in malignant gliomas. Neurology 81:1515–1522
-
(2013)
Neurology
, vol.81
, pp. 1515-1522
-
-
Wick, W.1
Meisner, C.2
Hentschel, B.3
-
26
-
-
84873345824
-
Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951
-
van den Bent MJ, Brandes AA, Taphoorn MJB et al (2013) Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951. J Clin Oncol 31:344–350
-
(2013)
J Clin Oncol
, vol.31
, pp. 344-350
-
-
Van Den Bent, M.J.1
Brandes, A.A.2
Taphoorn, M.3
-
27
-
-
84873338121
-
Phase III Trial of Chemoradiotherapy for Anaplastic Oligodendroglioma: Long-Term Results of RTOG 9402
-
Cairncross G, Wang M, Shaw E et al (2013) Phase III Trial of Chemoradiotherapy for Anaplastic Oligodendroglioma: Long-Term Results of RTOG 9402. J Clin Oncol 31:337–343
-
(2013)
J Clin Oncol
, vol.31
, pp. 337-343
-
-
Cairncross, G.1
Wang, M.2
Shaw, E.3
-
28
-
-
80051659072
-
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: An ANOCEF phase II trial
-
Gállego Pérez-Larraya J, Ducray F, Chinot O et al. Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. J Clin Oncol 2011 Aug 1;29(22):3050-5
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3050-3055
-
-
Gállego Pérez-Larraya, J.1
Ducray, F.2
Chinot, O.3
-
29
-
-
84864121917
-
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly
-
Reifenberger G, Hentschel B, Felsberg J et al (2012) Predictive impact of MGMT promoter methylation in glioblastoma of the elderly. Int J Cancer 131(6):1342–1350
-
(2012)
Int J Cancer
, vol.131
, Issue.6
, pp. 1342-1350
-
-
Reifenberger, G.1
Hentschel, B.2
Felsberg, J.3
-
30
-
-
84865558322
-
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: The Nordic randomised, phase 3 trial
-
Malmström A, Grønberg BH, Marosi C et al (2012) Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial. Lancet Oncol 13(9):916–926
-
(2012)
Lancet Oncol
, vol.13
, Issue.9
, pp. 916-926
-
-
Malmström, A.1
Grønberg, B.H.2
Marosi, C.3
-
31
-
-
84880678757
-
Malignant gliomas of elderly patients have a distinct molecular profile: An analysis of the NOA-08 study collective
-
for the Neurooncology Working Group (NOA) of the German Cancer Society
-
Wiestler B, Claus R, Hartlieb SA, Schliesser MG, Weiss EK, Hielscher T, Platten M, Dittmann LM, Meisner C, Felsberg J, Happold C, Simon M, Nikkhah G, Papsdorf K, Steinbach JP, Sabel M, Grimm C, Weichenhan D, Tews B, Reifenberger G, Capper D, Müller W, Plass C, Weller M, Wick W for the Neurooncology Working Group (NOA) of the German Cancer Society (2013) Malignant gliomas of elderly patients have a distinct molecular profile: an analysis of the NOA-08 study collective. Neurooncol 15(8):1017–1026
-
(2013)
Neurooncol
, vol.15
, Issue.8
, pp. 1017-1026
-
-
Wiestler, B.1
Claus, R.2
Hartlieb, S.A.3
Schliesser, M.G.4
Weiss, E.K.5
Hielscher, T.6
Platten, M.7
Dittmann, L.M.8
Meisner, C.9
Felsberg, J.10
Happold, C.11
Simon, M.12
Nikkhah, G.13
Papsdorf, K.14
Steinbach, J.P.15
Sabel, M.16
Grimm, C.17
Weichenhan, D.18
Tews, B.19
Reifenberger, G.20
Capper, D.21
Müller, W.22
Plass, C.23
Weller, M.24
Wick, W.25
more..
-
32
-
-
84862192200
-
Early measures of cognitive function predict survival in patients with newly diagnosed glioblastoma
-
Johnson DR et al (2012) Early measures of cognitive function predict survival in patients with newly diagnosed glioblastoma. Neuro Oncol 14:808–816
-
(2012)
Neuro Oncol
, vol.14
, pp. 808-816
-
-
Johnson, D.R.1
-
33
-
-
84899760157
-
Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH
-
Cairncross JG, Wang M, Jenkins RB, Shaw EG, Giannini C, Brachman DG, Buckner JC, Fink KL, Souhami L, Laperriere NJ, Huse JT, Mehta MP, Curran WJ Jr (2014) Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol 32(8):783–790
-
(2014)
J Clin Oncol
, vol.32
, Issue.8
, pp. 783-790
-
-
Cairncross, J.G.1
Wang, M.2
Jenkins, R.B.3
Shaw, E.G.4
Giannini, C.5
Brachman, D.G.6
Buckner, J.C.7
Fink, K.L.8
Souhami, L.9
Laperriere, N.J.10
Huse, J.T.11
Mehta, M.P.12
Curran, W.J.13
-
34
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
Hartmann C, Hentschel B, Wick W et al (2010) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120:707–718
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
35
-
-
84891948402
-
The mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy
-
Weiler M, Blaes J, Pusch S et al (2014) The mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci USA 111:409–414
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 409-414
-
-
Weiler, M.1
Blaes, J.2
Pusch, S.3
-
36
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle D, Popovici-Muller J, Palaskas N, Turcan S, Grommes C et al (2013) An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 340 (6132):626–630
-
(2013)
Science
, vol.340
, Issue.6132
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
Turcan, S.4
Grommes, C.5
-
37
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumor immunity
-
accepted
-
Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, Menn O, Osswald M, Oezen I, Ott M, Keil M, Balss J, Rauschenbach K, Grabowska AK, Vogler I, Diekmann J, Trautwein N, Eichmüller S, Okun J, Stefanovic S, Riemer AB, Sahin U, Friese M, Beckhove P, von Deimling A, Wick W, Platten M (2014). A vaccine targeting mutant IDH1 induces antitumor immunity. Nature accepted
-
(2014)
Nature
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
Sahm, F.4
Wiestler, B.5
Quandt, J.6
Menn, O.7
Osswald, M.8
Oezen, I.9
Ott, M.10
Keil, M.11
Balss, J.12
Rauschenbach, K.13
Grabowska, A.K.14
Vogler, I.15
Diekmann, J.16
Trautwein, N.17
Eichmüller, S.18
Okun, J.19
Stefanovic, S.20
Riemer, A.B.21
Sahin, U.22
Friese, M.23
Beckhove, P.24
Von Deimling, A.25
Wick, W.26
Platten, M.27
more..
-
38
-
-
84873362485
-
Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: A report from EORTC study 26951
-
Erdem-Eraslan L, Gravendeel LA, de Rooi J et al (2013) Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951. J Clin Oncol 31 (3):328–336
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 328-336
-
-
Erdem-Eraslan, L.1
Gravendeel, L.A.2
De Rooi, J.3
-
39
-
-
84883464949
-
ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis
-
Wiestler B, Capper D, Holland-Letz T et al (2013) ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis. Acta Neuropathol 126:443–451
-
(2013)
Acta Neuropathol
, vol.126
, pp. 443-451
-
-
Wiestler, B.1
Capper, D.2
Holland-Letz, T.3
|