γδ T cell surveillance via CD1 molecules

Trends in Immunology

Volumn 35, Issue 12, 2014, Pages 613-621

  Luoma, Adrienne M ^a   Castro, Caitlin D ^a   Adams, Erin J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

CD1d; Crystallography; Lipids; Restriction; T cell receptor; T cells

Indexed keywords

CD1 ANTIGEN; LIPID; T LYMPHOCYTE RECEPTOR;

GAMMA DELTA T LYMPHOCYTE; HUMAN; LYMPHOCYTE SUBPOPULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; NONHUMAN; PATHOGEN CLEARANCE; REVIEW; T LYMPHOCYTE ACTIVATION; TISSUE REPAIR;

EID: 84916208655     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2014.09.003     Document Type: Review

References (94)

1. Chien Y.H., et al. gammadelta T cells: first line of defense and beyond. Annu. Rev. Immunol. 2014, 32:121-155.
2. Vantourout P., Hayday A. Six-of-the-best: unique contributions of gammadelta T cells to immunology. Nat. Rev. Immunol. 2013, 13:88-100.
3. McVay L.D., Carding S.R. Generation of human gammadelta T-cell repertoires. Crit. Rev. Immunol. 1999, 19:431-460.
4. Tanaka Y., et al. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature 1995, 375:155-158.
5. Constant P., et al. Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands. Science 1994, 264:267-270.
6. Sandstrom A., et al. The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vgamma9Vdelta2 T cells. Immunity 2014, 40:490-500.
7. Bai L., et al. The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vdelta1 TCR. Eur. J. Immunol. 2012, 42:2505-2510.
8. Russano A.M., et al. Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J. Allergy Clin. Immunol. 2006, 117:1178-1184.
9. Agea E., et al. Human CD1-restricted T cell recognition of lipids from pollens. J. Exp. Med. 2005, 202:295-308.
10. Mangan B.A., et al. Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vdelta3 T cells. J. Immunol. 2013, 191:30-34.
11. Dieude M., et al. Cardiolipin binds to CD1d and stimulates CD1d-restricted gammadelta T cells in the normal murine repertoire. J. Immunol. 2011, 186:4771-4781.
12. Luoma A.M., et al. Crystal structure of Vdelta1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human gammadelta T cells. Immunity 2013, 39:1032-1042.
13. Uldrich A.P., et al. CD1d-lipid antigen recognition by the gammadelta TCR. Nat. Immunol. 2013, 14:1137-1145.
14. Takahashi T., Suzuki T. Role of sulfatide in normal and pathological cells and tissues. J. Lipid Res. 2012, 53:1437-1450.
15. Bendelac A., et al. The biology of NKT cells. Annu. Rev. Immunol. 2007, 25:297-336.
16. Garcia K.C., Adams E.J. How the T cell receptor sees antigen - a structural view. Cell 2005, 122:333-336.
17. Wang J.H., Reinherz E.L. The structural basis of alphabeta T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function. Immunol. Rev. 2012, 250:102-119.
18. Adams E.J., et al. Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22. Science 2005, 308:227-231.
19. Wucherpfennig K.W., et al. Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling. Cold Spring Harb. Perspect. Biol. 2010, 2:a005140.
20. van der Merwe P.A., Davis S.J. Molecular interactions mediating T cell antigen recognition. Annu. Rev. Immunol. 2003, 21:659-684.
21. Godfrey D.I., et al. The fidelity, occasional promiscuity, and versatility of T cell receptor recognition. Immunity 2008, 28:304-314.
22. Girardi E., et al. Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens. Nat. Immunol. 2012, 13:851-856.
23. Patel O., et al. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat. Immunol. 2012, 13:857-863.
24. Lopez-Sagaseta J., et al. The molecular basis for mucosal-associated invariant T cell recognition of MR1 proteins. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E1771-E1778.
25. Borg N.A., et al. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 2007, 448:44-49.
26. Adams E.J., Lopez-Sagaseta J. The immutable recognition of CD1d. Immunity 2011, 34:281-283.
27. Gapin L. Check MAIT. J. Immunol. 2014, 192:4475-4480.
28. Rossjohn J., et al. Recognition of CD1d-restricted antigens by natural killer T cells. Nat. Rev. Immunol. 2012, 12:845-857.
29. Kinjo Y., et al. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature 2005, 434:520-525.
30. Chien Y.H., et al. T-cell receptor delta gene rearrangements in early thymocytes. Nature 1987, 330:722-727.
31. Elliott J.F., et al. The adult T-cell receptor delta-chain is diverse and distinct from that of fetal thymocytes. Nature 1988, 331:627-631.
32. Rock E.P., et al. CDR3 length in antigen-specific immune receptors. J. Exp. Med. 1994, 179:323-328.
33. Hayday A.C. Gammadelta T cells and the lymphoid stress-surveillance response. Immunity 2009, 31:184-196.
34. Sutton C.E., et al. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
35. Wencker M., et al. Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness. Nat. Immunol. 2014, 15:80-87.
36. Russano A.M., et al. CD1-restricted recognition of exogenous and self-lipid antigens by duodenal gammadelta+ T lymphocytes. J. Immunol. 2007, 178:3620-3626.
37. Chodaczek G., et al. Body-barrier surveillance by epidermal gammadelta TCRs. Nat. Immunol. 2012, 13:272-282.
38. Perera L., et al. Expression of nonclassical class I molecules by intestinal epithelial cells. Inflamm. Bowel Dis. 2007, 13:298-307.
39. Sakakibara N., et al. Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma. Cancer Res. 1989, 49:335-339.
40. Liu Y., et al. Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. Mol. Cancer 2010, 9:186.
41. Sugiyama T., et al. Enhanced expression of sulfatide, a sulfated glycolipid, in well-differentiated endometrial adenocarcinoma. Int. J. Gynecol. Cancer 2012, 22:1192-1197.
42. Petry K., et al. Sulfated lipids represent common antigens on the surface of Trypanosoma cruzi and mammalian tissues. Mol. Biochem. Parasitol. 1988, 30:113-121.
43. Goren M.B., et al. Prevention of phagosome-lysosome fusion in cultured macrophages by sulfatides of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 1976, 73:2510-2514.
44. Gilleron M., et al. Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis. J. Exp. Med. 2004, 199:649-659.
45. Adams E.J. Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them. Curr. Opin. Immunol. 2014, 26:1-6.
46. Champsaur M., Lanier L.L. Effect of NKG2D ligand expression on host immune responses. Immunol. Rev. 2010, 235:267-285.
47. Groh V., et al. Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science 1998, 279:1737-1740.
48. Wu J., et al. T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells. J. Immunol. 2002, 169:1236-1240.
49. Xu B., et al. Crystal structure of a gammadelta T-cell receptor specific for the human MHC class I homolog MICA. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:2414-2419.
50. Schweighoffer E., Fowlkes B.J. Positive selection is not required for thymic maturation of transgenic gamma delta T cells. J. Exp. Med. 1996, 183:2033-2041.
51. Porcelli S., et al. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature 1989, 341:447-450.
52. Bluestone J.A., et al. Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4- CD8- T lymphocytes. J. Exp. Med. 1988, 168:1899-1916.
53. Matis L.A., et al. Major histocompatibility complex-linked specificity of gamma delta receptor-bearing T lymphocytes. Nature 1987, 330:262-264.
54. Willcox C.R., et al. Cytomegalovirus and tumor stress surveillance by binding of a human gammadelta T cell antigen receptor to endothelial protein C receptor. Nat. Immunol. 2012, 13:872-879.
55. Spada F.M., et al. Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. J. Exp. Med. 2000, 191:937-948.
56. Matis L.A., et al. Structure and specificity of a class II MHC alloreactive gamma delta T cell receptor heterodimer. Science 1989, 245:746-749.
57. Sciammas R., et al. Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell. J. Immunol. 1994, 152:5392-5397.
58. Tanaka Y., et al. Nonpeptide ligands for human gamma delta T cells. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:8175-8179.
59. Scotet E., et al. Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. Immunity 2005, 22:71-80.
60. Bruder J., et al. Target specificity of an autoreactive pathogenic human gammadelta-T cell receptor in myositis. J. Biol. Chem. 2012, 287:20986-20995.
61. Zeng X., et al. gammadelta T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response. Immunity 2012, 37:524-534.
62. Adams E.J., Luoma A.M. The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules. Annu. Rev. Immunol. 2013, 31:529-561.
63. Bendelac A., et al. CD1 recognition by mouse NK1+ T lymphocytes. Science 1995, 268:863-865.
64. Ly D., Moody D.B. The CD1 size problem: lipid antigens, ligands, and scaffolds. Cell. Mol. Life Sci. 2014, 10.1007/s00018-014-1603-6.
65. Koch M., et al. The crystal structure of human CD1d with and without alpha-galactosylceramide. Nat. Immunol. 2005, 6:819-826.
66. Zeng Z., et al. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 1997, 277:339-345.
67. Zajonc D.M., et al. Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A. Nat. Immunol. 2003, 4:808-815.
68. Zajonc D.M., et al. Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat. Immunol. 2005, 6:810-818.
69. Scharf L., et al. The 2.5 a structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity 2010, 33:853-862.
70. Gadola S.D., et al. Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat. Immunol. 2002, 3:721-726.
71. Salio M., et al. Biology of CD1- and MR1-restricted T cells. Annu. Rev. Immunol. 2014, 32:323-366.
72. De Libero G., Mori L. Novel insights into lipid antigen presentation. Trends Immunol. 2012, 33:103-111.
73. Mori L., De Libero G. T cells specific for lipid antigens. Immunol. Res. 2012, 53:191-199.
74. Dougan S.K., et al. CD1 expression on antigen-presenting cells. Curr. Top. Microbiol. Immunol. 2007, 314:113-141.
75. Kawano T., et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 1997, 278:1626-1629.
76. Wieland Brown L.C., et al. Production of alpha-galactosylceramide by a prominent member of the human gut microbiota. PLoS Biol. 2013, 11:e1001610.
77. Van Rhijn I., et al. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat. Immunol. 2013, 14:706-713.
78. Ly D., et al. CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens. J. Exp. Med. 2013, 210:729-741.
79. Kasmar A.G., et al. Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. J. Immunol. 2013, 191:4499-4503.
80. Kasmar A.G., et al. CD1b tetramers bind alphabeta T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J. Exp. Med. 2011, 208:1741-1747.
81. de Lalla C., et al. High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells. Eur. J. Immunol. 2011, 41:602-610.
82. de Jong A., et al. CD1a-autoreactive T cells are a normal component of the human alphabeta T cell repertoire. Nat. Immunol. 2010, 11:1102-1109.
83. de Jong A., et al. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat. Immunol. 2014, 15:177-185.
84. Pellicci D.G., et al. Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity 2009, 31:47-59.
85. Tilloy F., et al. An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals. J. Exp. Med. 1999, 189:1907-1921.
86. Reantragoon R., et al. Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J. Exp. Med. 2013, 210:2305-2320.
87. Eckle S.B., et al. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J. Exp. Med. 2014, 211:1585-1600.
88. Lopez-Sagaseta J., et al. MAIT recognition of a stimulatory bacterial antigen bound to MR1. J. Immunol. 2013, 191:5268-5277.
89. Patel O., et al. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat. Commun. 2013, 4:2142.
90. Corbett A.J., et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 2014, 509:361-365.
91. Gold M.C., et al. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. J. Exp. Med. 2014, 211:1601-1610.
92. Treiner E., et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 2003, 422:164-169.
93. Kjer-Nielsen L., et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature 2012, 491:717-723.
94. Cui J., et al. Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science 1997, 278:1623-1626.