Vascular smooth muscle cell proliferation depends on caveolin-1-regulated polyamine uptake

Bioscience Reports

Volumn 34, Issue 6, 2014, Pages 729-741

  Grossi, Mario ^a   Rippe, Catarina ^a   Sathanoori, Ramasri ^b   Swärd, Karl ^a   Forte, Amalia ^c   Erlinge, David ^b   Persson, Lo ^a   Hellstrand, Per ^a   Nilsson, Bengt Olof ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Caveolin 1; Cell cycle; Ornithine decarboxylase; Polyamine; Polyamine transporter; Vascular smooth muscle cell

Indexed keywords

CALPONIN; CARRIER PROTEIN; CAVEOLIN 1; ORNITHINE DECARBOXYLASE; POLYAMINE; PROTEIN SLC43A1; PROTEIN SLC7A1; TRANSGELIN; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AMINO ACID TRANSPORTER; CALCIUM BINDING PROTEIN; DNA; MUSCLE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ORNITHINE DECARBOXYLASE GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; UPREGULATION; VASCULAR SMOOTH MUSCLE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CAROTID ARTERY; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; SURGERY; WESTERN BLOTTING; WISTAR RAT;

AMINO ACID TRANSPORT SYSTEMS, BASIC; ANIMALS; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CAROTID ARTERIES; CAVEOLIN 1; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DNA; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; ORNITHINE DECARBOXYLASE; POLYAMINES; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84915821316     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20140140     Document Type: Article

References (33)

1. Lindsay, A. C., Biasiolli, L., Knight, S., Cunnington, C., Robson, M. D., Neubauer, S., Kennedy, J., Handa, A. and Choudhury, R. P. (2014) Non-invasive imaging of carotid arterial restenosis using 3 T cardiovascular magnetic resonance. J. Cardiovasc. Magn. Reson. 16, 5
2. Wessely, R. (2010) New drug-eluting stent concenpts. Nat. Rev. Cardiol. 7, 194-203
3. Liang, M., Ekblad, E., Hellstrand, P. and Nilsson, B. O. (2004) Polyamine synthesis inhibition attenuates vascular smooth muscle cell migration. J. Vasc. Res. 41, 141-147
4. Kucharzewska, P., Welch, J. E., Svensson, K. J. and Belting, M. (2010) Ornithine decarboxylase and extracellular polyamines regulate microvascular sprouting and actin cytoskeleton dynamics in endothelial cells. Exp. Cell Res. 316, 2683-2691
5. Forte, A., Hellstrand, P., Nilsson, B. O., Grossi, M., Rossi, F. and Cipollaro, M. (2011) The polyamine pathway as a potential target for vascular diseases: focus on restenosis. Curr. Vasc. Pharmacol. 9, 706-714
6. Grossi, M., Persson, L., Swärd, K., Turczyńska, K. M., Forte, A., Hellstrand, P. and Nilsson, B. O. (2014) Inhibition of polyamine formation antagonizes vascular smooth muscle cell proliferation and preserves the contractile phenotype. Basic Clin. Pharmacol. Toxicol. 115, 379-388
7. Casero, R. A. and Pegg, A. E. (2009) Polyamine catabolism and disease. Biochem. J. 421, 323-338
8. Brooks, W. H. (2012) Autoimmune disease and polyamines. Clin. Rev. Allergy Immunol. 42, 58-70
9. Soda, K. (2011) The mechanisms by which polyamines accelerate tumor spread. J. Exp. Clin. Cancer Res. 30, 95
10. Abdulhussein, A. A. and Wallace, H. M. (2014) Polyamines and membrane transporters. Amino Acids 46, 655-660
11. Uemura, T., Stringer, D. E., Blohm-Mangone, K. A. and Gerner, E. W. (2010) Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G517-G522
12. Roy, U. K., Rial, N. S., Kachel, K. L. and Gerner, E. W. (2008) Activated K-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis. Mol. Carcinog. 47, 538-553
13. Matthews, L. C., Taggart, M. J. and Westwood, M. (2008) Modulation of caveolin-1 expression can affect signalling through the phosphatidylinositol 3-kinase/Akt pathway and cellular proliferation in response to insulin-like growth factor I. Endocrinology 149, 5199-5208
14. Gosens, R., Stelmack, G. L., Dueck, G., McNeill, K. D., Yamasaki, A., Gerthoffer, W. T., Unruh, H., Gounni, A. S., Zaagsma, J. and Halayko, A. J. (2006) Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L523-L534
15. Hassan, G. S., Williams, T. M., Frank, P. G. and Lisanti, M. P. (2006) Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction. Am. J. Physiol. Heart Circ. Physiol. 290, H2393-H2401
16. Schwencke, C., Schmeisser, A., Walter, C., Wachter, R., Pannach, S., Weck, B., Braun-Dullaeus, R. C., Kasper, M. and Strasser, R. H. (2005) Decreased caveolin-1 in atheroma: loss of antiproliferative control of vascular smooth muscle cells in atherosclerosis. Cardiovasc. Res. 68, 128-135
17. Forte, A., Grossi, M., Turczynska, K. M., Svedberg, K., Rinaldi, B., Donniacuo, M., Holm, A., Baldetorp, B., Vicchio, M., De Feo, M. et al. (2013) Local inhibition of ornithine decarboxylase reduces vascular stenosis in a murine model of carotid injury. Int. J. Cardiol. 168, 3370-3380
18. Shakirova, Y., Bonnevier, J., Albinsson, S., Adner, M., Rippe, B., Broman, J., Arner, A. and Swärd, K. (2006) Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1. Am. J. Physiol. Cell Physiol. 291, C1326-C1335
19. Forte, A., Di Micco, G., Galderisi, U., Guarino, F. M., Cipollaro, M., De Feo, M., Gregorio, R., Bianco, M. R., Vollono, C., Esposito, F. et al. (2001) Molecular analysis of arterial stenosis in rat carotids. J. Cell Physiol. 186, 307-313
20. Chamley-Campbell, J. H., Campbell, G. R. and Ross, R. (1979) The smooth muscle cell in culture. Physiol. Rev. 59, 1-61
21. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275
22. Forte, A., Finicelli, M., Grossi, M., Vicchio, M., Alessio, N., Santè, P., De Feo, M., Cotrufo, M., Berrino, L., Rossi, F. et al. (2010) DNA damage and repair in a model of rat vascular injury. Clin. Sci. 118, 473-485
23. Zeidan, A., Nordström, I., Albinsson, S., Malmqvist, U., Swärd, K. and Hellstrand, P. (2003) Stretch-induced contractile differentiation of vascular smooth muscle: sensitivity to actin polymerization inhibitors. Am. J. Physiol. Cell Physiol. 284, C1387-C1396
24. Sharpe, J. G. and Seidel, E. R. (2005) Polyamines are absorbed through a y + amino acid carrier in rat intestinal epithelial cells. Amino Acids 29, 245-253
25. Swärd, K., Sadegh, M. K., Mori, M., Erjefält, J. S. and Rippe, C. (2013) Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. Physiol. Rep. 1, e00008
26. Pegg, A. E. (1986) Recent advances in the biochemistry of polyamines in eukaryotes. Biochem. J. 234, 249-262
27. Poulin, R., Casero, R. A. and Soulet, D. (2011) Recent advances in the molecular biology of metazoan polyamne transport. Amino Acids 42, 711-723
28. Chamley-Campbell, J. H., Campbell, G. R. and Ross, R. (1981) Phenotype-dependent response of cultured aortic smooth muscle to serum mitogens. J. Cell Biol. 89, 379-383
29. Albinsson, S., Shakirova, Y., Rippe, A., Baumgarten, M., Rosengren, B. I., Rippe, C., Hallmann, R., Hellstrand, P., Rippe, B. and Swärd, K. (2007) Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R1222-R1231
30. Swärd, K., Albinsson, S. and Rippe, C. (2014) Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE 9, e92428
31. Galbiati, F., Volonte, D., Engelman, J. A., Watanabe, G., Burk, R., Pestell, R. G. and Lisanti, M. P. (1998) Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. EMBO J. 17, 6633-6648
32. Koleske, A. J., Baltimore, D. and Lisanti, M. P. (1995) Reduction of caveolin and caveolae in oncogenically transformed cells. Proc. Natl. Acad. Sci. U. S. A. 92, 1381-1385
33. Forte, A., Finicelli, M., De Luca, P., Quarto, C., Onorati, F., Santè, P., Renzulli, A., Galderisi, U., Berrino, L., De Feo, M. et al. (2008) Expression profiles in surgically-induced carotid stenosis: a combined transcriptomic and proteomic investigation. J. Cell. Mol. Med. 12, 1956-1973