메뉴 건너뛰기




Volumn 145, Issue , 2015, Pages 133-138

All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause

Author keywords

Androgens; Breast cancer; Dehydroepiandrosterone; Estrogens; Intracrinology; Menopause

Indexed keywords

ANDROGEN; ESTRADIOL; PRASTERONE; SEX HORMONE; AROMATASE INHIBITOR; ESTROGEN; HYDROCORTISONE; PROGESTERONE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STEROID;

EID: 84915817059     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2014.06.001     Document Type: Review
Times cited : (182)

References (50)
  • 1
    • 33947224108 scopus 로고    scopus 로고
    • Drospirenone-containing hormone therapy for postmenopausal women. Perspective on current data
    • D.F. Archer Drospirenone-containing hormone therapy for postmenopausal women. Perspective on current data J. Reprod. Med. 52 2007 159 164
    • (2007) J. Reprod. Med. , vol.52 , pp. 159-164
    • Archer, D.F.1
  • 3
    • 0034992739 scopus 로고    scopus 로고
    • Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate
    • W.H. Utian, D. Shoupe, G. Bachmann, J.V. Pinkerton, and J.H. Pickar Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate Fertil. Steril. 75 2001 1065 1079
    • (2001) Fertil. Steril. , vol.75 , pp. 1065-1079
    • Utian, W.H.1    Shoupe, D.2    Bachmann, G.3    Pinkerton, J.V.4    Pickar, J.H.5
  • 4
    • 0029806162 scopus 로고    scopus 로고
    • Research on the menopause in the 1990s
    • H. O. Scientific Group W. World Health Organization Geneva
    • W.H.O. Scientific Group Research on the menopause in the 1990s WHO technical report series No 866 1996 World Health Organization Geneva
    • (1996) WHO Technical Report Series No 866
  • 5
    • 34447623585 scopus 로고    scopus 로고
    • Drug insight: Breast cancer prevention and tissue-targeted hormone replacement therapy
    • F. Labrie Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy Nat. Clin. Pract. Endocrinol. Metabol. 3 2007 584 593
    • (2007) Nat. Clin. Pract. Endocrinol. Metabol. , vol.3 , pp. 584-593
    • Labrie, F.1
  • 7
    • 52949143539 scopus 로고    scopus 로고
    • Randomized, multicenter, double-blind, placebo-controlled trial to evaluate the efficacy and safety of synthetic conjugated estrogens B for the treatment of vulvovaginal atrophy in healty postmenopausal women
    • J.A. Simon, K.Z. Reape, S. Wininger, and H. Hait Randomized, multicenter, double-blind, placebo-controlled trial to evaluate the efficacy and safety of synthetic conjugated estrogens B for the treatment of vulvovaginal atrophy in healty postmenopausal women Fertil. Steril. 90 2008 1132 1138
    • (2008) Fertil. Steril. , vol.90 , pp. 1132-1138
    • Simon, J.A.1    Reape, K.Z.2    Wininger, S.3    Hait, H.4
  • 8
    • 78649441596 scopus 로고    scopus 로고
    • Overview of menopause and aging
    • The North American Menopause Society Mayfield Heights (OH)
    • NAMS: Professional Education Committee Overview of menopause and aging Menopause Practice: A Clinician's Guide 2007 The North American Menopause Society Mayfield Heights (OH) 9 17
    • (2007) Menopause Practice: A Clinician's Guide , pp. 9-17
  • 10
    • 0034282411 scopus 로고    scopus 로고
    • Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age
    • E.B. Gold, B. Sternfeld, J.L. Kelsey, C. Brown, C. Mouton, and N. Reame Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age Am. J. Epidemiol. 152 2000 463 473
    • (2000) Am. J. Epidemiol. , vol.152 , pp. 463-473
    • Gold, E.B.1    Sternfeld, B.2    Kelsey, J.L.3    Brown, C.4    Mouton, C.5    Reame, N.6
  • 12
    • 61349087285 scopus 로고    scopus 로고
    • Menopause-specific questionnaire assessment in US population-based study shows negative impact on health-related quality of life
    • R.E. Williams, K.B. Levine, L. Kalilani, J. Lewis, and R.V. Clark Menopause-specific questionnaire assessment in US population-based study shows negative impact on health-related quality of life Maturitas 62 2009 153 159
    • (2009) Maturitas , vol.62 , pp. 153-159
    • Williams, R.E.1    Levine, K.B.2    Kalilani, L.3    Lewis, J.4    Clark, R.V.5
  • 13
    • 78651411484 scopus 로고    scopus 로고
    • Wide distribution of the serum dehydroepiandrosterone and sex steroid levels in postmenopausal women: Role of the ovary?
    • F. Labrie, C. Martel, and J. Balser Wide distribution of the serum dehydroepiandrosterone and sex steroid levels in postmenopausal women: role of the ovary? Menopause 18 2011 30 43
    • (2011) Menopause , vol.18 , pp. 30-43
    • Labrie, F.1    Martel, C.2    Balser, J.3
  • 14
    • 0023681542 scopus 로고
    • Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate
    • C. Labrie, A. Bélanger, and F. Labrie Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate Endocrinology 123 1988 1412 1417
    • (1988) Endocrinology , vol.123 , pp. 1412-1417
    • Labrie, C.1    Bélanger, A.2    Labrie, F.3
  • 16
    • 77953643561 scopus 로고    scopus 로고
    • DHEA after menopause-sole source of sex steroids and potential sex steroid deficiency treatment
    • F. Labrie DHEA after menopause-sole source of sex steroids and potential sex steroid deficiency treatment Menopause Management 19 2010 14 24
    • (2010) Menopause Management , vol.19 , pp. 14-24
    • Labrie, F.1
  • 17
    • 0022169886 scopus 로고
    • Complete androgen blockade for the treatment of prostate cancer
    • V.T. de Vita, S. Hellman, S.A. Rosenberg, J.B. Lippincott Philadelphia
    • F. Labrie, A. Dupont, and A. Bélanger Complete androgen blockade for the treatment of prostate cancer V.T. de Vita, S. Hellman, S.A. Rosenberg, Important Advances in Oncology 1985 J.B. Lippincott Philadelphia 193 217
    • (1985) Important Advances in Oncology , pp. 193-217
    • Labrie, F.1    Dupont, A.2    Bélanger, A.3
  • 19
    • 85014442074 scopus 로고    scopus 로고
    • Assessment of steroidogenic pathways that do not require testosterone as intermediate
    • V. Luu-The Assessment of steroidogenic pathways that do not require testosterone as intermediate Horm. Mol. Biol. Clin. Invest. 5 2011 161 165
    • (2011) Horm. Mol. Biol. Clin. Invest. , vol.5 , pp. 161-165
    • Luu-The, V.1
  • 20
    • 0024401194 scopus 로고
    • Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate
    • C. Labrie, J. Simard, H.F. Zhao, A. Bélanger, G. Pelletier, and F. Labrie Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate Endocrinology 124 1989 2745 2754
    • (1989) Endocrinology , vol.124 , pp. 2745-2754
    • Labrie, C.1    Simard, J.2    Zhao, H.F.3    Bélanger, A.4    Pelletier, G.5    Labrie, F.6
  • 21
    • 0027056168 scopus 로고
    • Structure, function and tissue-specific gene expression of 3é-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues
    • F. Labrie, J. Simard, V. Luu-The, A. Bélanger, and G. Pelletier Structure, function and tissue-specific gene expression of 3é-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues J. Steroid Biochem. Mol. Biol. 43 1992 805 826
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.43 , pp. 805-826
    • Labrie, F.1    Simard, J.2    Luu-The, V.3    Bélanger, A.4    Pelletier, G.5
  • 23
    • 0028785906 scopus 로고
    • The human type II 17β-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species
    • Y. Labrie, F. Durocher, Y. Lachance, C. Turgeon, J. Simard, and C. Labrie The human type II 17β-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species DNA Cell Biol. 14 1995 849 861
    • (1995) DNA Cell Biol. , vol.14 , pp. 849-861
    • Labrie, Y.1    Durocher, F.2    Lachance, Y.3    Turgeon, C.4    Simard, J.5    Labrie, C.6
  • 24
    • 0029593494 scopus 로고
    • Characteristics of human types 1, 2 and 3 17b-hydroxysteroid dehydrogenase activities: Oxidation-reduction and inhibition
    • V. Luu-The, Y. Zhang, D. Poirier, and F. Labrie Characteristics of human types 1, 2 and 3 17b-hydroxysteroid dehydrogenase activities: oxidation-reduction and inhibition J. Steroid Biochem. Mol. Biol. 55 1995 581 587
    • (1995) J. Steroid Biochem. Mol. Biol. , vol.55 , pp. 581-587
    • Luu-The, V.1    Zhang, Y.2    Poirier, D.3    Labrie, F.4
  • 25
    • 0000589419 scopus 로고    scopus 로고
    • The 3β-hydroxysteroid dehydrogenase/isomerase gene family: Lessons from type II 3β-HSD congenital deficiency
    • Suppl.
    • Labrie F, Simard J, Luu-The V, Bélanger A, Pelletier G, Morel Y, et al.; The 3β-hydroxysteroid dehydrogenase/isomerase gene family: lessons from type II 3β-HSD congenital deficiency. Signal Transduction in Testicular Cells, Ernst Schering Research Foundation Workshop. 1996; Suppl. 2:185-218.
    • (1996) Signal Transduction in Testicular Cells, Ernst Schering Research Foundation Workshop , vol.2 , pp. 185-218
    • Labrie F, S.1
  • 27
    • 0019468206 scopus 로고
    • Inability of human endometrium or myometrium to aromatize androstenedione
    • P.M. Baxendale, M.J. Reed, and V.H. James Inability of human endometrium or myometrium to aromatize androstenedione J. Steroid Biochem. 14 1981 305 306
    • (1981) J. Steroid Biochem. , vol.14 , pp. 305-306
    • Baxendale, P.M.1    Reed, M.J.2    James, V.H.3
  • 28
    • 23944493604 scopus 로고    scopus 로고
    • Regulation of aromatase expression in estrogen-responsive breast and uterine disease: From bench to treatment
    • S.E. Bulun, Z. Lin, G. Imir, S. Amin, M. Demura, and B. Yilmaz Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment Pharmacol. Rev. 57 2005 359 383
    • (2005) Pharmacol. Rev. , vol.57 , pp. 359-383
    • Bulun, S.E.1    Lin, Z.2    Imir, G.3    Amin, S.4    Demura, M.5    Yilmaz, B.6
  • 29
    • 0028032138 scopus 로고
    • Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues
    • K. Toda, E.R. Simpson, C.R. Mendelson, Y. Shizuta, and M.W. Kilgore Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues Mol. Endocrinol. 8 1994 210 217
    • (1994) Mol. Endocrinol. , vol.8 , pp. 210-217
    • Toda, K.1    Simpson, E.R.2    Mendelson, C.R.3    Shizuta, Y.4    Kilgore, M.W.5
  • 31
    • 29144445284 scopus 로고    scopus 로고
    • The post-menopausal ovary displays a unique pattern of steroidogenic enzyme expression
    • J.C. Havelock, W.E. Rainey, K.D. Bradshaw, and B.R. Carr The post-menopausal ovary displays a unique pattern of steroidogenic enzyme expression Hum. Reprod. 21 2006 309 317
    • (2006) Hum. Reprod. , vol.21 , pp. 309-317
    • Havelock, J.C.1    Rainey, W.E.2    Bradshaw, K.D.3    Carr, B.R.4
  • 32
    • 1542617044 scopus 로고    scopus 로고
    • Co-evolution of steroidogenic and steroid-inactivating enzymes and adrenal and sex steroid receptors
    • M.E. Baker Co-evolution of steroidogenic and steroid-inactivating enzymes and adrenal and sex steroid receptors Mol. Cell. Endocrinol. 215 2004 55 62
    • (2004) Mol. Cell. Endocrinol. , vol.215 , pp. 55-62
    • Baker, M.E.1
  • 33
    • 84875184564 scopus 로고    scopus 로고
    • DHEA and intracrinology at menopause, a positive choice for evolution of the human species
    • F. Labrie, and C. Labrie DHEA and intracrinology at menopause, a positive choice for evolution of the human species Climacteric 16 2013 205 213
    • (2013) Climacteric , vol.16 , pp. 205-213
    • Labrie, F.1    Labrie, C.2
  • 37
    • 0001657785 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The postmenopausal estrogen/progestin interventions (PEPI) trial. The writing group for the PEPI trial
    • Writing Group For The Trial T.
    • The Writing Group for the Trial Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The postmenopausal estrogen/progestin interventions (PEPI) trial. The writing group for the PEPI trial JAMA 275 1996 370 375
    • (1996) JAMA , vol.275 , pp. 370-375
  • 38
    • 0023005581 scopus 로고
    • Steroid and gonadotropin levels in women during the peri-menopausal years
    • C. Longcope, C. Franz, C. Morello, R. Baker, and C.C. Johnston Jr. Steroid and gonadotropin levels in women during the peri-menopausal years Maturitas 8 1986 189 196
    • (1986) Maturitas , vol.8 , pp. 189-196
    • Longcope, C.1    Franz, C.2    Morello, C.3    Baker, R.4    Johnston, C.C.5
  • 39
    • 0034457514 scopus 로고    scopus 로고
    • A prospective longitudinal study of serum testosterone dehydroepiandrosterone sulfate and sex hormone binding globulin levels through the menopause transition
    • H.G. Burger, E.C. Dudley, J. Cui, L. Dennerstein, and J.C. Hopper A prospective longitudinal study of serum testosterone dehydroepiandrosterone sulfate and sex hormone binding globulin levels through the menopause transition J. Clin. Endocrin. Metab. 85 2000 2832 2838
    • (2000) J. Clin. Endocrin. Metab. , vol.85 , pp. 2832-2838
    • Burger, H.G.1    Dudley, E.C.2    Cui, J.3    Dennerstein, L.4    Hopper, J.C.5
  • 40
    • 0028801626 scopus 로고
    • A longitudinal study of the perimenopausal transition: Altered profiles of steroid and pituitary hormones, SHBG and bone mineral density
    • G. Rannevik, S. Jeppsson, O. Johnell, B. Bjerre, Y. Laurell-Borulf, and L. Svanberg A longitudinal study of the perimenopausal transition: altered profiles of steroid and pituitary hormones, SHBG and bone mineral density Maturitas 21 1995 103 113
    • (1995) Maturitas , vol.21 , pp. 103-113
    • Rannevik, G.1    Jeppsson, S.2    Johnell, O.3    Bjerre, B.4    Laurell-Borulf, Y.5    Svanberg, L.6
  • 41
    • 73349115224 scopus 로고    scopus 로고
    • Intravaginal dehydroepiandrosterone (prasterone), a physiological and highly efficient treatment of vaginal atrophy
    • F. Labrie, D. Archer, C. Bouchard, M. Fortier, L. Cusan, and J.L. Gomez Intravaginal dehydroepiandrosterone (prasterone), a physiological and highly efficient treatment of vaginal atrophy Menopause 16 2009 907 922
    • (2009) Menopause , vol.16 , pp. 907-922
    • Labrie, F.1    Archer, D.2    Bouchard, C.3    Fortier, M.4    Cusan, L.5    Gomez, J.L.6
  • 42
    • 72249101980 scopus 로고    scopus 로고
    • Effect on intravaginal dehydroepiandrosterone (prasterone) on libido and sexual dysfunction in postmenopausal women
    • F. Labrie, D. Archer, C. Bouchard, M. Fortier, L. Cusan, and J.L. Gomez Effect on intravaginal dehydroepiandrosterone (prasterone) on libido and sexual dysfunction in postmenopausal women Menopause 16 2009 923 931
    • (2009) Menopause , vol.16 , pp. 923-931
    • Labrie, F.1    Archer, D.2    Bouchard, C.3    Fortier, M.4    Cusan, L.5    Gomez, J.L.6
  • 43
    • 29344452196 scopus 로고    scopus 로고
    • Differential effects of estradiol, progesterone, and testosterone on vaginal structural integrity
    • M.A. Pessina, R.F. Hoyt Jr.; I. Goldstein, and A.M. Traish Differential effects of estradiol, progesterone, and testosterone on vaginal structural integrity Endocrinology 147 2006 61 69
    • (2006) Endocrinology , vol.147 , pp. 61-69
    • Pessina, M.A.1    Hoyt, R.F.2    Goldstein, I.3    Traish, A.M.4
  • 44
    • 84881090583 scopus 로고    scopus 로고
    • Androgenic action of dehydroepiandrosterone (DHEA) on nerve density in the ovariectomized rat vagina
    • G. Pelletier, J. Ouellet, C. Martel, and F. Labrie Androgenic action of dehydroepiandrosterone (DHEA) on nerve density in the ovariectomized rat vagina J. Sex. Med. 10 2013 1908 1914
    • (2013) J. Sex. Med. , vol.10 , pp. 1908-1914
    • Pelletier, G.1    Ouellet, J.2    Martel, C.3    Labrie, F.4
  • 45
    • 73349105263 scopus 로고    scopus 로고
    • Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration
    • F. Labrie, D. Archer, C. Bouchard, M. Fortier, L. Cusan, and J.L. Gomez Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration Menopause 16 2009 897 906
    • (2009) Menopause , vol.16 , pp. 897-906
    • Labrie, F.1    Archer, D.2    Bouchard, C.3    Fortier, M.4    Cusan, L.5    Gomez, J.L.6
  • 47
    • 55349137697 scopus 로고    scopus 로고
    • Corrigendum to: Effect of intravaginal DHEA on serum DHEA and eleven of its metabolites in postmenopausal women
    • F. Labrie, L. Cusan, J.L. Gomez, I. Côté, R. Bérubé, and P. Bélanger Corrigendum to: effect of intravaginal DHEA on serum DHEA and eleven of its metabolites in postmenopausal women J. Steroid Biochem. Mol. Biol. 112 2008 169
    • (2008) J. Steroid Biochem. Mol. Biol. , vol.112 , pp. 169
    • Labrie, F.1    Cusan, L.2    Gomez, J.L.3    Côté, I.4    Bérubé, R.5    Bélanger, P.6
  • 48
    • 84883201802 scopus 로고    scopus 로고
    • Intravaginal prasterone (DHEA) provides local action without clinically significant changes in serum concentrations of estrogens or androgens
    • F. Labrie, C. Martel, R. Berube, I. Cote, C. Labrie, and L. Cusan Intravaginal prasterone (DHEA) provides local action without clinically significant changes in serum concentrations of estrogens or androgens J. Steroid Biochem. Mol. Biol. 138 2013 359 367
    • (2013) J. Steroid Biochem. Mol. Biol. , vol.138 , pp. 359-367
    • Labrie, F.1    Martel, C.2    Berube, R.3    Cote, I.4    Labrie, C.5    Cusan, L.6
  • 49
    • 77951782692 scopus 로고    scopus 로고
    • Minimized estradiol absorption with ultra-low-dose 10 microg 17beta-estradiol vaginal tablets
    • M. Eugster-Hausmann, J. Waitzinger, and D. Lehnick Minimized estradiol absorption with ultra-low-dose 10 microg 17beta-estradiol vaginal tablets Climacteric 13 2010 219 227
    • (2010) Climacteric , vol.13 , pp. 219-227
    • Eugster-Hausmann, M.1    Waitzinger, J.2    Lehnick, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.