Whole-house arsenic water treatment provided more effective arsenic exposure reduction than point-of-use water treatment at New Jersey homes with arsenic in well water

Science of the Total Environment

Volumn 505, Issue , 2015, Pages 1361-1369

  Spayd, Steven E ^a   Robson, Mark G ^a,b,c   Buckley, Brian T ^a,b  

^a RUTGERS SCHOOL OF PUBLIC HEALTH   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

Arsenic; Body burden; New Jersey; Point of entry; Point of use; Water treatment

Indexed keywords

ARSENIC; BODY FLUIDS; HOUSES; POTABLE WATER; SPEED CONTROL; WATER TREATMENT;

ARSENIC CONCENTRATION; ARSENIC IN DRINKING WATERS; BODY BURDEN; NEW JERSEY; OBSERVATIONAL STUDY; POINT OF ENTRIES; POINT-OF-USE; RESIDENTIAL HOMES;

CHEMICALS REMOVAL (WATER TREATMENT);

DRINKING WATER; ARSENIC; WATER POLLUTANT; WELL WATER;

ARSENIC; POLLUTION EXPOSURE; WATER TREATMENT; WATER USE; WELL WATER;

ABSORPTION; ADULT; ANALYSIS OF COVARIANCE; ARSENIC POISONING; ARTICLE; BIOLOGICAL MONITORING; BODY BURDEN; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL PROTECTION; FEMALE; FLUID INTAKE; GEOGRAPHIC DISTRIBUTION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OBSERVATIONAL STUDY; OXIDATION REDUCTION POTENTIAL; PROPENSITY SCORE; SEDIMENT; UNITED STATES; URINALYSIS; WATER ANALYSIS; WATER QUALITY; WATER TREATMENT; ANALYSIS; CHEMISTRY; PREVENTION AND CONTROL; PROCEDURES; STATISTICS AND NUMERICAL DATA; WATER MANAGEMENT; WATER POLLUTANT;

NEW JERSEY; UNITED STATES;

ARSENIC; ENVIRONMENTAL EXPOSURE; NEW JERSEY; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION; WATER WELLS;

EID: 84915786449     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2014.06.026     Document Type: Article

References (29)

1. ACGIH Biological Exposure Indices 2001, 7th ed.
2. AWWA Research Foundation POU/POE implementation feasibility study for arsenic treatment Available:, [accessed 2014]. http://www.waterrf.org/PublicReportLibrary/91083F.pdf.
3. Bernstam L., Lan C.H., Lee J., Nriagu J.O. Effects of arsenic on human keratinocytes: Morphological, physiological, and precursor incorporation studies. Environ Res 2002, 89:220-235.
4. Caldwell K.L., Jones R.L., Verdon C.P., Jarrett J.M., Caudill S.P., Osterloh J.D. Levels of urinary total and speciated arsenic in the US population: National Health and Nutrition Examination Survey 2003-2004. J Expos Sci Environ Epidemiol 2008, 19:59.
5. D'Agostino R.B. Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med 1998, 17:2265-2281.
6. Ghisletta P., Spini D. An Introduction to Generalized Estimating Equations and an Application to Assess Selectivity Effects in a Longitudinal Study on Very Old Individuals. J Educ Behav Stat 2004, 29:421.
7. Hanley J.A., Negassa A., Edwardes M.D., Forrester J.E. Statistical analysis of correlated data using generalized estimating equations: An orientation. Am J Epidemiol 2003, 157:364-375.
8. Hopenhayn-Rich C., Biggs M.L., Kalman D.A., Moore L.E., Smith A.H. Arsenic methylation patterns before and after changing from high to lower concentrations of arsenic in drinking water. Environ Health Perspect 1996, 104:1200-1207.
9. Iyengar V., Woittiez J. Trace elements in human clinical specimens: Evaluation of literature data to identify reference values. Clin Chem 1988, 34:474-481.
10. Klaassen C.D. Casarett and Doull's Toxicology 2001, 226-229. McGraw Hill. 6th ed.
11. LabCorp Arsenic exposure profile, urine Available:, [accessed 2013]. https://www.labcorp.com/wps/portal/provider/testmenu/.
12. Marshall W.J., Bangert S.K. Clinical biochemistry: Metabolic and clinical aspects 2008, Elsevier Health Sciences.
13. National Research Council Arsenic in Drinking Water 1999, National Academy Press, Washington, D.C.
14. NJDEP Safe Drinking Water Act rules readoption with amendments: N.J.A.C. 7:10. December 6, 2004 2004, New Jersey Register, December 6, 2004.
15. NJDEP Private Well Testing Act Program Well Test Results for September 2002 - April 2007 Available:, [accessed 2013]. http://www.state.nj.us/dep/pwta/pwta_report_final.pdf.
16. NJDEP Division of Water Supply and Geoscience, Private Well Testing Act Frequently Asked Questions Available:, [accessed 2014]. http://www.nj.gov/dep/watersupply/pwta/pwta_faq.htm#3q13.
17. NJDEP Office of Science, Private Well Testing Act Web Site Available:, [accessed 2013]. http://www.nj.gov/dep/dsr/pwta/.
18. Nriagu J., Bernstam L. Biomarkers of arsenic effects on gene expression in human skin 2004, AWWA Research Foundation.
19. Rahman M.S., Hall L.L., Hughes M.F. In vitro percutaneous absorption of monosodium methanearsonate and disodium methanearsonate in female B6C3F1 mice. Toxicol In Vitro 1994, 8:441-448.
20. Serfes M.E., Spayd S.E., Herman G.C. Chapter 13 - Arsenic occurrence, sources, mobilization, and transport in groundwater in the Newark basin of New Jersey. Advances in arsenic research. Integration of experimental and observational studies and implications for mitigation 2005, 175-190. American Chemical Society, Washington, DC. P.A. O'Day, D. Vlassopoulos, X. Meng, L.G. Benning (Eds.).
21. Spayd S.E. Arsenic Water Treatment for Residential Wells in New Jersey Available:, [accessed 2013]. http://www.state.nj.us/dep/pwta/Arsenic_Treatment.pdf.
22. Spayd S.E., Robson M.G., Xie R., Buckley B.T. Importance of Arsenic Speciation in Populations Exposed to Arsenic in Drinking Water. Hum Ecol Risk Assess Int J 2012, 18(6):1271-1291.
23. Tao S.S.H., Bolger P.M. Dietary arsenic intakes in the United States: FDA Total Diet Study, September 1991-December 1996. Food Addit Contam 1999, 16:465-472.
24. Tietz N.W. Clinical guide to laboratory tests 1990, W B Saunders Co. 2nd ed.
25. USEPA National primary drinking water regulations: Arsenic and clarifications to compliance and new source contaminants monitoring Available:, [accessed 2013]. http://www.epa.gov/fedrgstr/EPA-WATER/2001/January/Day-22/w1668.htm.
26. Weisel C.P., Jo W.K. Ingestion, inhalation, and dermal exposures to chloroform and trichloroethene from tap water. Environ Health Perspect 1996, 104:48-51.
27. Wester R.C., Maibach H.I., Sedik L., Melendres J., Wade M. In vivo and in vitro percutaneous absorption and skin decontamination of arsenic from water and soil. Fundam Appl Toxicol 1993, 20:336-340.
28. Wester R.C., Hui X., Barbadillo S., Maibach H.I., Lowney Y.W., Schoof R.A., et al. In vivo percutaneous absorption of arsenic from water and CCA-treated wood residue. Toxicol Sci 2004, 79:287-295.
29. Xie R., Johnson W., Spayd S., Hall G., Buckley B. Determination of total toxic arsenic species in human urine using hydride generation inductively coupled plasma mass spectrometry. J Anal At Spectrom 2007, 22:553-560.