Dexamethasone protects neonatal hypoxic-ischemic brain injury via L-PGDS-dependent PGD2-DP1-pERK signaling pathway

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Gonzalez Rodriguez, Pablo J ^a   Li, Yong ^a   Martinez, Fabian ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; LIPOCALIN TYPE PROSTAGLANDIN D SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROSTAGLANDIN D SYNTHASE; PROSTAGLANDIN D2; PROSTANOID RECEPTOR; UNCLASSIFIED DRUG; ISOMERASE; LIPOCALIN; NEUROPROTECTIVE AGENT; PROSTAGLANDIN R2 D-ISOMERASE; TRANSCRIPTION FACTOR DP1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; FEMALE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN; DRUG EFFECTS; ENZYME INDUCTION; ENZYMOLOGY; HYPOXIA-ISCHEMIA, BRAIN; METABOLISM; PHYSIOLOGY; PRECLINICAL STUDY; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; BRAIN; DEXAMETHASONE; DRUG EVALUATION, PRECLINICAL; ENZYME INDUCTION; FEMALE; HYPOXIA-ISCHEMIA, BRAIN; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MALE; MAP KINASE SIGNALING SYSTEM; NEUROPROTECTIVE AGENTS; PROSTAGLANDIN D2; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR DP1; UP-REGULATION;

EID: 84915745381     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114470     Document Type: Article

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