In vitro assessment of cytotoxicity, antioxidant, and anti-inflammatory activities of Ricinus communis (euphorbiaceae) leaf extracts

Evidence-based Complementary and Alternative Medicine

Volumn 2014, Issue , 2014, Pages

  Nemudzivhadi, Vhutshilo ^a   Masoko, Peter ^a  

^a UNIVERSITY OF LIMPOPO   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; DICHLOROMETHANE; FREE RADICAL; HEXANE; METHANOL; RICINUS COMMUNIS EXTRACT;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; PLANT LEAF; RICINUS COMMUNIS; SKIN FIBROBLAST;

EID: 84914689063     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2014/625961     Document Type: Article

References (33)

1. Shai L. J., McGaw L. J., Masoko P., Eloff J. N., Antifungal and antibacterial activity of seven traditionally used South African plant species active against Candida albicans. South African Journal of Botany 2008 74 4 677 684 10.1016/j.sajb.2008.04.003 2-s2.0-53049084774
2. Huda-Faujan N., Noriham A., Norrakiah A. S., Babji A. S., Antioxidant activity of plants methanolic extracts containing phenolic compounds. African Journal of Biotechnology 2009 8 3 484 489 2-s2.0-60549108902
3. Patel V. R., Patel P. P., Kujal S. S., Antioxidant activity of some selected medicinal plants in western Region of India. Advances in Biological Research 2010 4 1 23 26
4. Talib W. H., Mahasneh A. M., Antiproliferative activity of plant extracts used against cancer in traditional medicine. Scientia Pharmaceutica 2010 78 1 33 45 10.3797/scipharm.0912-11 2-s2.0-77749234278
5. Morobe I. C., Mthethwa N. S., Bisi-Johnson M. A., Cytotoxic effects and safety profiles of extracts of active medicinal plants from South Africa. Journal of Microbiology Research 2012 2 6 176 182 10.5923/j.microbiology.20120206.04
6. Jiménez-Estrada M., Velázquez-Contreras C., Garibay-Escobar A., Sierras-Canchola D., Lapizco-Vázquez R., Ortiz-Sandoval C., Burgos-Hernández A., Robles-Zepeda R. E., In vitro antioxidant and antiproliferative activities of plants of the ethnopharmacopeia from northwest of Mexico. BMC Complementary and Alternative Medicine 2013 13, article 12 10.1186/1472-6882-13-12 2-s2.0-84872118406
7. Kratchanova M., Denev P., Ciz M., Lojek A., Mihailov A., Evaluation of antioxidant activity of medicinal plants containing polyphenol compounds. Comparison of two extraction systems. Acta Biochimica Polonica 2010 57 2 229 234 2-s2.0-77956520632
8. Magama S., Lieta M. I., Asita A. O., Antioxidant and free radical scavenging properties of four plant species used in traditional medicine in Lesotho. International Journal of Medicinal Plant Research 2013 2 3 170 178
9. Aguirre A., Borneo R., Antioxidant effects of four native medicinal plants collected in Córdoba. Molecular Medicinal Chemistry 2010 12 1 3
10. Kumar D. A., Kshitij C., Nishteswar K., Ricinus communis Linn.-an Ayurveda and research perspectives. International Journal of Universal Pharmacy and Life Sciences 2013 3 3 71 90
11. Masoko P., Eloff J. N., Screening of twenty-four South African Combretum and six Terminalia species (Combretaceae) for antioxidant activites. African Journal of Traditional, Complementary and Alternative Medicines 2007 4 2 231 239 2-s2.0-33947216854
12. Bichra M., El-Modafar C., El-Abbassi A., Bouamama H., Benkhalti F., Antioxidant activities and phenolic profile of six Moroccan selected herbs. Journal of Microbiology, Biotechnology and Food Sciences 2013 2 4 2320 2338
13. Iqbal J., Zaib S., Farooq U., Khan A., Bibi I., Suleman S., Antioxidant, Antimicrobial, and free radical scavenging potential of aerial parts of Periploca aphylla and Ricinus communis. ISRN Pharmacology 2012 2012 6 563267 10.5402/2012/563267
14. Christy Jeyaseelan E., Justin Jashothan P. T., In vitro control of Staphylococcus aureus (NCTC 6571) and Escherichia coli (ATCC 25922) by Ricinus communis L. Asian Pacific Journal of Tropical Biomedicine 2012 2 9 717 721 10.1016/S2221-1691(12)60216-0 2-s2.0-84862327964
15. Taur D. J., Waghmare M. G., Bandal R. S., Patil R. Y., Antinociceptive activity of Ricinus communis L. leaves. Asian Pacific Journal of Tropical Biomedicine 2011 1 2 139 141 10.1016/S2221-1691(11)60012-9 2-s2.0-79952376578
16. Rekha D., Tamil-Selvi S., Bharathidasan R., Panneerselvam A., Ilakkiya R., Jayapal R., Study of medicinal plants used from koothanoallur and marakkadai, Thiruvarur district of Tamil nadu, India. Hygeia Journal for Drugs and Medicines 2013 5 1 164 170
17. Shokeen P., Anand P., Murali Y. K., Tandon V., Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions. Food and Chemical Toxicology 2008 46 11 3458 3466 10.1016/j.fct.2008.08.020 2-s2.0-54449083139
18. Kadri A., Gharsallah N., Damak M., Gdoura R., Chemical composition and in vitro antioxidant properties of essential oil of Ricinus communis L. Journal of Medicinal Plants Research 2011 5 8 1466 1470 2-s2.0-79958009015
19. Zarai Z., Chobba I. B., Mansour R. B., Békir A., Gharsallah N., Kadri A., Essential oil of the leaves of Ricinus communis L.: in vitro cytotoxicity and antimicrobial properties. Lipids in Health and Disease 2012 11, article 102 10.1186/1476-511X-11-102 2-s2.0-84864822221
20. Nemudzivhadi V., Isolation and characterization of antibacterial and antioxidant compounds from Ricinus communis leaves [M.S. thesis] 2014 Limpopo, South Africa University of Limpopo (Turfloop campus)
21. Kotzé M., Eloff J. N., Extraction of antibacterial compounds from Combretum microphyllum (Combretaceae). South African Journal of Botany 2002 68 1 62 67 2-s2.0-0036282424
22. Deby C., Magotteaux G., Relationship between essential fatty acids and tissue antioxidant levels in mice. Comptes Rendus des Séances de la Société de Biologie et de Ses Filiales 1970 164 12 2675 2681 2-s2.0-0014888183
23. van den Berg R., Haenen G. R. M. M., van den Berg H., Bast A., Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chemistry 1999 66 4 511 517 10.1016/S0308-8146(99)00089-8 2-s2.0-0032987218
24. Mosaddegh M., Esmaeili S., Naghibi F., Moghadam M. H., Haeri A., Pirani A., Moazzeni H., Ethnomedical survey and cytotoxic activity of medicinal plant extracts used in Kohgiluyeh and Boyerahmad Province in Iran. Journal of Herbs, Spices and Medicinal Plants 2012 18 3 211 221 10.1080/10496475.2012.671801 2-s2.0-84863482277
25. Vijayarathna S., Sasidharan S., Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines. Asian Pacific Journal of Tropical Biomedicine 2012 2 10 826 829 10.1016/S2221-1691(12)60237-8 2-s2.0-84862743402
26. Rajamurugan R., Deepa V., Sivashanmugam M., Raghavan C. M., Phytochemistry, antioxidant and antibacterial activities of medicinal plants-a comparative study. International Journal of Current Research and Review 2013 5 2 8 19
27. Surveswaran S., Cai Y.-Z., Corke H., Sun M., Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants. Food Chemistry 2007 102 3 938 953 2-s2.0-33846196634 10.1016/j.foodchem.2006.06.033
28. Rana M., Dhamija H., Prashar B., Sharma S., Ricinus communis L.-a review. International Journal of PharmTech Research 2012 4 4 1706 1711 2-s2.0-84875040580
29. Salem A. N. B., Zyed R., Ali L. M., Nidhal S., Souad S., Mahjoub A., Cytotoxic effect of nanoparticles synthesized from Salvia officinalis L. and Ricinus communis aqueous extracts against vero cell line and evaluation of their antioxidant activities. African Journal of Biotechnology 2012 11 52 11530 11534
30. Ilavarasan R., Mallika M., Venkataraman S., Anti-inflammatory and free radical scavenging activity of Ricinus communis root extract. Journal of Ethnopharmacology 2006 103 3 478 480 10.1016/j.jep.2005.07.029 2-s2.0-31344480664
31. 4 on lipopolysaccharide induced proliferation and reactive oxygen species production in RAW264.7 macrophages through modulation of G-CSF secretion. Inflammation Research 2007 56 8 324 333 10.1007/s00011-007-7012-7 2-s2.0-34547751500
32. Karlsson M., Kurz T., Brunk U. T., Nilsson S. E., Frennesson C. I., What does the commonly used DCF test for oxidative stress really show? Biochemical Journal 2010 428 2 183 190 10.1042/BJ20100208 2-s2.0-77952573307
33. Saini A. K., Goyal R., Gauttam V. K., Kalia A. N., Evaluation of anti-inflammatory potential of Ricinus communis Linn leaves extracts and its flavonoids content in Wistar rats. Journal of Chemical and Pharmaceutical Research 2010 2 5 690 695