Racial difference in cochlear pigmentation is associated with hearing loss risk

Otology and Neurotology

Volumn 35, Issue 9, 2014, Pages 1509-1514

  Sun, Daniel Q ^a   Zhou, Xin ^b   Lin, Frank R ^a   Francis, Howard W ^a   Carey, John P ^a   Chien, Wade W ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Cochlea; Hearing lossV Melanin; Race; Temporal bone. Copyright

Indexed keywords

MELANIN;

ADULT; AFRICAN AMERICAN; AGED; AUDIOMETRY; CAUCASIAN; COCHLEA; ETHNOLOGY; FEMALE; HEARING IMPAIRMENT; HUMAN; MALE; METABOLISM; MIDDLE AGED; PIGMENTATION; RISK FACTOR; VERY ELDERLY;

ADULT; AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; AUDIOMETRY; COCHLEA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEARING LOSS; HUMANS; MALE; MELANINS; MIDDLE AGED; PIGMENTATION; RISK FACTORS;

EID: 84914179605     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0000000000000564     Document Type: Article

References (27)

1. Lin FR, Thorpe R, Gordon-Salant S, et al. Hearing loss prevalence and risk factors among older adults in the United States. J Gerontol A Biol Sci Med Sci 2011;66A:582-90.
2. Lin FR, Maas P, Chien W, et al. Association of skin color, race/ethnicity, and hearing loss among adults in the USA. J Assoc Res Otolaryngol 2012;13:109-17.
3. Helzner EP, Cauley JA, Pratt SR, et al. Race and sex differences in age-related hearing loss: the Health, Aging and Body Composition Study. J Am Geriatr Soc 2005;53:2119-27.
4. Jerger J, Jerger S, Pepe P, et al. Race difference in susceptibility to noise-induced hearing loss. Am J Otol 1986;7:425-9.
5. Ishii EK, Talbott EO. Race/ethnicity differences in the prevalence of noise-induced hearing loss in a group of metal fabricating workers. J Occup Environ Med 1998;40:661-6.
6. Kim HJ, Gratton MA, Lee JH, et al. Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct. J Neurosci 2013;33:14601-6.
7. Steel KP, Barkway C. Another role for melanocytes: their importance for normal stria vascularis development in the mammalian inner ear. Development 1989;107:453-63.
8. Ohlemiller KK, Rybak Rice ME, Lett JM, et al. Absence of strial melanin coincides with age-associated marginal cell loss and endocochlear potential decline. Hear Res 2009;249:1-14.
9. Lezirovitz K, Nicastro FS, Pardono E, et al. Is autosomal recessive deafness associated with oculocutaneous albinism a "coincidence syndrome"? J Hum Genet 2006;51:716-20.
10. Leger S, Balguerie X, Goldenberg A, et al. Novel and recurrent non-truncating mutations of the MITF basic domain: genotypic and phenotypic variations in Waardenburg and Tietz syndromes. Eur J Hum Genet 2012;20:584-7.
11. Wolff D. Melanin in the inner ear. Arch Otolaryngol 1931;14:195-211.
12. Seaman BJ, Guardiani EA, Brewer CC, et al. Audiovestibular dysfunction associated with adoptive cell immunotherapy for melanoma. Otolaryngol Head Neck Surg 2012;147:744-9.
13. Navarrete CM, Ruah CB, Schachern P, et al. Normal and meta-static melanin in the temporal bone. Am J Otolaryngol 1995; 16:33-9.
14. Crowe SJ, Guild SR, Polvogt LM. Observations on the pathology of high-tone deafness. Bull Johns Hopkins Hosp 1934;54:315.
15. Nager GT. Pathology of the Ear and Temporal Bone. Baltimore, Williams & Wilkins, 1993.
16. Bush WD, Simon JD. Quantification of Ca(2+) binding to melanin supports the hypothesis that melanosomes serve a functional role in regulating calcium homeostasis. Pigment Cell Res 2007;20:134-9.
17. Laurell G, Ekborn A, Viberg A, et al. Effects of a single high dose of cisplatin on the melanocytes of the stria vascularis in the guinea pig. Audiol Neurootol 2007;12:170-8.
18. Murillo-Cuesta S, Contreras J, Zurita E, et al. Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice. Pigment Cell Melanoma Res 2010;23:72-83.
19. Conlee JW, Parks TN, Schwartz IR, et al. Comparative anatomy of melanin pigment in the stria vascularis. Evidence for a distinction between melanocytes and intermediate cells in the cat. Acta Otolaryngol 1989;107:48-58.
20. Covell WP, Rogers JB. Pathologic changes in the inner ears of senile guinea pigs. Laryngoscope 1957;67:118-29.
21. Schraermeyer U, Heimann K. Current understanding on the role of retinal pigment epithelium and its pigmentation. Pigment Cell Res 1999;12:219-36.
22. Menardo J, Tang Y, Ladrech S, et al. Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea. Antioxid Redox Signal 2012;16:263-74.
23. Barhanin J, Lesage F, Guillemare E, et al. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 1996;384:78-80.
24. Shaddock LC, Hamernik RP, Axelsson A. Cochlear vascular and sensory cell changes induced by elevated temperature and noise. Am J Otolaryngol 1984;5:99-107.
25. Nakamura F. Electrophysiological and cytochemical study on ototoxicity of dihydrostreptomycin. Ann Otol Rhinol Laryngol 1957; 66:1080-112.
26. Pauler M, Schuknecht HF, White JA. Atrophy of the stria vascularis as a cause of sensorineural hearing loss. Laryngoscope 1988;98:754-9.
27. Ohlemiller KK. Contributions of mouse models to understanding of age- and noise-related hearing loss. Brain Res 2006;1091:89-102.