Allelic variation in HLA-DRB1* loci in Syrian pemphigus vulgaris patients

International Journal of Dermatology

Volumn 53, Issue 12, 2014, Pages 1460-1463

  Harfouch, Elham ^a   Daoud, Saleh ^a  

^a DAMASCUS UNIVERSITY   (Syrian Arab Republic)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DRB1 ANTIGEN;

ADULT; ALLELE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; GENOTYPE; HLA TYPING; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PEMPHIGUS VULGARIS; POLYMERASE CHAIN REACTION; SKIN BIOPSY; SYRIAN; ADOLESCENT; AGED; FEMALE; GENETIC VARIABILITY; GENETICS; MALE; MIDDLE AGED; PEMPHIGUS; SYRIAN ARAB REPUBLIC; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALLELES; FEMALE; GENETIC VARIATION; GENOTYPE; HLA-DRB1 CHAINS; HUMANS; MALE; MIDDLE AGED; PEMPHIGUS; SEROEPIDEMIOLOGIC STUDIES; SYRIA; YOUNG ADULT;

EID: 84914176673     PISSN: 00119059     EISSN: 13654632     Source Type: Journal    
DOI: 10.1111/ijd.12184     Document Type: Article

References (20)

1. Grando AS. Pemphigus autoimmunity: hypotheses and realities. Autoimmunity 2012; 45: 7-35.
2. Pan M, Liu X, Zheng J. The pathogenic role of autoantibodies in pemphigus vulgaris. Clin Exp Dermatol 2011; 36: 703-707.
3. Wada N, Nishifuji K, Yamada T, et al. Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T cell tolerance. J Invest Dermatol 2011; 131: 410-417.
4. Zakka LR, Keskin DB, Reche P, et al. Relationship between target antigens and major histocompatibility complex (MHC) class II genes in producing two pathogenic antibodies simultaneously. Clin Exp Immunol 2010; 162: 224-236.
5. Sinha AA. The genetics of pemphigus. Dermatol Clin 2011; 29: 381-391.
6. Tron F, Gilbert D, Joly P, et al. Immunogenetics of pemphigus: an update. Autoimmunity 2006; 39: 521-530.
7. Tunca M, Musabak U, Sagkan RI, et al. Association of human leukocyte antigen class II alleles with pemphigus vulgaris in a Turkish population. J Dermatol 2010; 37: 246-250.
8. Shams S, Amirzargar AA, Yousefi M, et al. HLA class II (DRB, DQA1 and DQB1) allele and haplotype frequencies in the patients with pemphigus vulgaris. J Clin Immunol 2009; 29: 175-179.
9. Brick C, Belgnaoui FZ, Atouf O, et al. Pemphigus and HLA in Morocco. Transfus Clin Biol 2007; 14: 402-406.
10. Glorio R, Rodriguez Costa G, Haas R, et al. HLA haplotypes and class II molecular alleles in Argentinian patients with pemphigus vulgaris. J Cutan Med Surg 2002; 6: 422-426.
11. Weber R, Monteiro F, Preuhs-Filho G, et al. HLA-DRB1*04:02, DRB1*08:04 and DRB1*14 alleles associated to pemphigus vulgaris in southeastern Brazilian population. Tissue Antigens 2011; 78: 92-93.
12. Saenz-Cantele AM, Fernandez-Mestre M, Montagnani S, et al. HLA-DRB1*0402 haplotypes without DQB1*0302 in Venezuelan patients with pemphigus vulgaris. Tissue Antigens 2007; 69: 318-325.
13. Lee E, Lendas KA, Chow S, et al. Disease relevant HLA class II alleles isolated by genotypic, haplotypic, and sequence analysis in North American Caucasians with pemphigus vulgaris. Hum Immunol 2006; 67: 125-139.
14. Lombardi ML, Mercuro O, Ruocco V, et al. Common human leukocyte antigen alleles in pemphigus vulgaris and pemphigus foliaceus Italian patients. J Invest Dermatol 1999; 113: 107-110.
15. Yamamoto T, Ikeda K, Sasaoka S, et al. Human leukocyte antigen genotypes and antibody profiles associated with familial pemphigus in Japanese. J Dermatol 2011; 38: 711-716.
16. Zhou SH, Lin L, Jin PY, et al. Association between HLA-DRB1, DQB1 genes and pemphigus vulgaris in Chinese Hans. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2003; 20: 79-81.
17. Veldman CM, Gebhard KL, Uter W, et al. T cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals. J Immunol 2004; 172: 3883-3889.
18. Veldman C, Stauber A, Wassmuth R, et al. Dichotomy of autoreactive Th1 and Th2 cell responses to desmoglein 3 in patients with pemphigus vulgaris (PV) and healthy carriers of PV-associated HLA class II alleles. J Immunol 2003; 170: 635-642.
19. Capon F, Bharkhada J, Cochrane NE, et al. Evidence of an association between desmoglein 3 haplotypes and pemphigus vulgaris. Br J Dermatol 2006; 154: 67-70.
20. Narbutt J, Sysa-Jedrzejowska A, Borowiec M, et al. Tumor necrosis factor-alpha polymorphism as one of the complex inherited factors in pemphigus. Mediators Inflamm 2003; 12: 303-307.