Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes :A prospective study

Anesthesiology

Volumn 121, Issue 5, 2014, Pages 959-968

  Sasaki, Nobuo ^a   Meyer, Matthew J ^b   Malviya, Sanjana A ^b   Stanislaus, Anne B ^b   MacDonald, Teresa ^c   Doran, Mary E ^c   Igumenshcheva, Arina ^c   Hoang, Alan H ^b   Eikermann, Matthias ^b,d  

^a Showa General Hospital   (Japan)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATRACURIUM BESILATE; CISATRACURIUM; NEOSTIGMINE; NEUROMUSCULAR BLOCKING AGENT; OXYGEN; ROCURONIUM; VECURONIUM; CHOLINERGIC RECEPTOR STIMULATING AGENT;

ADULT; AGED; ARTICLE; ATELECTASIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; DRUG THERAPY; ELECTRIC PERIPHERAL NERVE STIMULATOR; FEMALE; FRACTION OF INSPIRED OXYGEN; GAS ANALYSIS PARAMETERS; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INCIDENCE; LENGTH OF STAY; LUNG EDEMA; MAJOR CLINICAL STUDY; MALE; NEOSTIGMINE REVERSAL; NEUROMUSCULAR TRANSMISSION; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; OXYGEN SATURATION; OXYGENATION; PATIENT MONITORING; PNEUMONIA; POSTOPERATIVE COMPLICATION; PREDICTION; PROSPECTIVE STUDY; RECOVERY ROOM; RESPIRATORY FAILURE; RESPIRATORY TRACT INTUBATION; SURGICAL MORTALITY; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DOSE RESPONSE; EXTUBATION; MIDDLE AGED; PATHOPHYSIOLOGY; POSTOPERATIVE COMPLICATIONS; RESPIRATORY INSUFFICIENCY; TREATMENT OUTCOME;

ADULT; AGED; AIRWAY EXTUBATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOSTIGMINE; NEUROMUSCULAR NONDEPOLARIZING AGENTS; PARASYMPATHOMIMETICS; POSTOPERATIVE COMPLICATIONS; PULMONARY ATELECTASIS; RESPIRATORY INSUFFICIENCY; TREATMENT OUTCOME;

EID: 84914171454     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000440     Document Type: Article

References (40)

1. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS: Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit. Anesth Analg 2008; 107:130-7
2. Herbstreit F, Peters J, Eikermann M: Impaired upper airway integrity by residual neuromuscular blockade: Increased airway collapsibility and blunted genioglossus muscle activity in response to negative pharyngeal pressure. Anesthesiology 2009; 110:1253-60
3. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS, Nisman M: Intraoperative acceleromyographic monitoring reduces the risk of residual neuromuscular blockade and adverse respiratory events in the postanesthesia care unit. Anesthesiology 2008; 109:389-98
4. Butterly A, Bittner EA, George E, Sandberg WS, Eikermann M, Schmidt U: Postoperative residual curarization from intermediate- acting neuromuscular blocking agents delays recovery room discharge. Br J Anaesth 2010; 105:304-9
5. Grosse-Sundrup M, Henneman JP, Sandberg WS, Bateman BT, Uribe JV, Nguyen NT, Ehrenfeld JM, Martinez EA, Kurth T, Eikermann M: Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: Prospective propensity score matched cohort study. BMJ 2012; 345:e6329
6. Meyer MJ, Bateman BT, Kurth T, Eikermann M: Neostigmine reversal doesn't improve postoperative respiratory safety. BMJ 2013; 346:f1460
7. Fuchs-Buder T, Claudius C, Skovgaard LT , Eriksson LI, Mirakhur RK, Viby-Mogensen J; 8th International Neuromuscular Meeting: Good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents II: The Stockholm revision. Acta Anaesthesiol Scand 2007; 51:789-808
8. Brull SJ, Ehrenwerth J, Silverman DG: Stimulation with submaximal current for train-of-four monitoring. Anesthesiology 1990; 72:629-32
9. Kopman AF, Yee PS, Neuman GG: Relationship of the trainof- four fade ratio to clinical signs and symptoms of residual paralysis in awake volunteers. Anesthesiology 1997; 86:765-71
10. Eriksson LI, Sundman E, Olsson R, Nilsson L, Witt H, Ekberg O, Kuylenstierna R: Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans: Simultaneous videomanometry and mechanomyography of awake human volunteers. Anesthesiology 1997; 87:1035-43
11. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB; National Institutes of Health, National Heart, Lung, and Blood Institute ARDS Network: Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS. Chest 2007; 132:410-7
12. Catterall M, Kazantzis G, Hodges M: The performance of nasal catheters and a face mask in oxygen therapy. Lancet 1967; 1:415-7
13. Naguib M, Lien CA: Pharmacology of muscle relaxants and their antagonists, Miller's Anesthesia, 6th edition, Miller RD, Fleisher LA, Johns RA, Savarese JJ, Wiener-Kronish JP, Young WL (eds.). Philadelphia, Churchill Livingstone/Elsevier, 2005, pp 481-572
14. Brueckmann B, Villa-Uribe JL, Bateman BT, Grosse-Sundrup M, Hess DR, Schlett CL, Eikermann M: Development and validation of a score for prediction of postoperative respiratory complications. Anesthesiology 2013; 118:1276-85
15. Bevan DR, Donati F, Kopman AF: Reversal of neuromuscular blockade. Anesthesiology 1992; 77:785-805
16. Barrow ME, Johnson JK: A study of the anticholinesterase and anticurare effects of some cholinesterase inhibitors. Br J Anaesth 1966; 38:420-31
17. Fiekers JF: Interactions of edrophonium, physostigmine and methanesulfonyl fluoride with the snake end-plate acetylcholine receptor-channel complex. J Pharmacol Exp Ther 1985; 234:539-49
18. Jones RK, Caldwell JE, Brull SJ, Soto RG: Reversal of profound rocuronium-induced blockade with sugammadex: A randomized comparison with neostigmine. Anesthesiology 2008; 109:816-24
19. Brull SJ, Murphy GS: Residual neuromuscular block: Lessons unlearned. Part II: Methods to reduce the risk of residual weakness. Anesth Analg 2010; 111:129-40
20. Kopman AF, Eikermann M: Antagonism of non-depolarising neuromuscular block: Current practice. Anaesthesia 2009; 64(suppl 1):22-30
21. Arndt GA, Gerry T, White P: Postoperative reparalysis after rocuronium following nebulized epinephrine. Can J Anaesth 1997; 44:321-4
22. Coveler LA, Gallacher BP: Postoperative rocuronium reparalysis. Can J Anaesth 1997; 44:1127
23. Donati F, Smith CE, Bevan DR: Dose-response relationships for edrophonium and neostigmine as antagonists of moderate and profound atracurium blockade. Anesth Analg 1989; 68:13-9
24. Ali HH, Utting JE, Gray TC: Quantitative assessment of residual antidepolarizing block. II. Br J Anaesth 1971; 43:478-85
25. Engbaek J, Ostergaard D, Skovgaard LT , Viby-Mogensen J: Reversal of intense neuromuscular blockade following infusion of atracurium. Anesthesiology 1990; 72:803-6
26. Kim KS, Cheong MA, Lee HJ, Lee JM: Tactile assessment for the reversibility of rocuronium-induced neuromuscular blockade during propofol or sevoflurane anesthesia. Anesth Analg 2004; 99:1080-5
27. Arbous MS, Meursing AE, van Kleef JW, de Lange JJ, Spoormans HH, Touw P, Werner FM, Grobbee DE: Impact of anesthesia management characteristics on severe morbidity and mortality. Anesthesiology 2005; 102:257-68; quiz 491-2
28. Eikermann M, Fassbender P, Malhotra A, Takahashi M, Kubo S, Jordan AS, Gautam S, White DP, Chamberlin NL: Unwarranted administration of acetylcholinesterase inhibitors can impair genioglossus and diaphragm muscle function. Anesthesiology 2007; 107:621-9
29. Herbstreit F, Zigrahn D, Ochterbeck C, Peters J, Eikermann M: Neostigmine/glycopyrrolate administered after recovery from neuromuscular block increases upper airway collapsibility by decreasing genioglossus muscle activity in response to negative pharyngeal pressure. Anesthesiology 2010; 113:1280-8
30. Payne JP, Hughes R, Al Azawi S: Neuromuscular blockade by neostigmine in anaesthetized man. Br J Anaesth 1980; 52:69-76
31. Khuri SF, Henderson WG, DePalma RG, Mosca C, Healey NA, Kumbhani DJ; Participants in the VA National Surgical Quality Improvement Program: Determinants of long-term survival after major surgery and the adverse effect of postoperative complications. Ann Surg 2005; 242:326-41; discussion 341-3
32. Dimick JB, Chen SL, Taheri PA, Henderson WG, Khuri SF, Campbell DA Jr: Hospital costs associated with surgical complications: A report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg 2004; 199:531-7
33. Kopman AF, Kopman DJ, Ng J, Zank LM: Antagonism of profound cisatracurium and rocuronium block: The role of objective assessment of neuromuscular function. J Clin Anesth 2005; 17:30-5
34. Sundman E, Witt H, Olsson R, Ekberg O, Kuylenstierna R, Eriksson LI: The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans: Pharyngeal videoradiography and simultaneous manometry after atracurium. Anesthesiology 2000; 92:977-84
35. Capron F, Fortier LP, Racine S, Donati F: Tactile fade detection with hand or wrist stimulation using train-of-four, double-burst stimulation, 50-hertz tetanus, 100-hertz tetanus, and acceleromyography. Anesth Analg 2006; 102:1578-84
36. Caldwell JE: Reversal of residual neuromuscular block with neostigmine at one to four hours after a single intubating dose of vecuronium. Anesth Analg 1995; 80:1168-74
37. Y ost CS, Maestrone E: Clinical concentrations of edrophonium enhance desensitization of the nicotinic acetylcholine receptor. Anesth Analg 1994; 78:520-6
38. L egendre P, Ali DW, Drapeau P: Recovery from open channel block by acetylcholine during neuromuscular transmission in zebrafish. J Neurosci 2000; 20:140-8
39. Krodel DJ, Bittner EA, Abdulnour R, Brown R, Eikermann M: Case scenario: Acute postoperative negative pressure pulmonary edema. Anesthesiology 2010; 113:200-7
40. Videira RL, Vieira JE: What rules of thumb do clinicians use to decide whether to antagonize nondepolarizing neuromuscular blocking drugs? Anesth Analg 2011; 113:1192-6