The roles of influenza virus antigens and the AS03 adjuvant in the 2009 pandemic vaccine associated with narcolepsy needs further investigation

Developmental Medicine and Child Neurology

Volumn 56, Issue 11, 2014, Pages 1041-1042

  Johansen, Kari ^a  

^a EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL ECDC   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; IMMUNOLOGICAL ADJUVANT; IMMUNOLOGICAL ADJUVANT AS03; INFLUENZA VACCINE; INFLUENZA VIRUS ANTIGEN; SQUALENE; THIOMERSAL; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

2009 H1N1 INFLUENZA; ARTICLE; CD4+ T LYMPHOCYTE; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; HUMAN; INFLUENZA VACCINATION; NARCOLEPSY; PRIORITY JOURNAL; FEMALE; MALE; VACCINATION; VIROLOGY;

FEMALE; HUMANS; INFLUENZA VACCINES; MALE; NARCOLEPSY; VACCINATION;

EID: 84914160653     PISSN: 00121622     EISSN: 14698749     Source Type: Journal    
DOI: 10.1111/dmcn.12543     Document Type: Article

References (7)

1. Director-General of the World Health Organization Dr Margaret Chan. World now at the start of 2009 influenza pandemic. http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6_20090611/en/ (accessed 15 July 2014).
2. Mereckiene J, Cotter S, Weber JT, et al. Influenza A(H1N1)pdm09 vaccination policies and coverage in Europe. Euro Surveill 2012; 17: pii: 20064.
3. European Centre for Disease Control. Enhanced monitoring of vaccine safety for 2009 pandemic vaccines. http://ecdc.europa.eu/en/healthtopics/pandemic_preparedness/2009_pandemic_vaccines/pages/vaccine-safety.aspx (accessed 15 July 2014).
4. Partinen M, Saarenpää-Heikkilä O, Ilveskoski I, et al. Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vacc-ination campaign in Finland. PLoS ONE 2012; 7: e33723.
5. Wijnans L, Lecomte C, de Vries C, et al. The incidence of narcolepsy in Europe: before, during, and after the influenza A(H1N1)pdm09 pandemic and vaccination campaigns. Vaccine 2013; 31: 1246-54.
6. Winstone AM, Stellitano L, Verity C, et al. Clinical features of narcolepsy in children vaccinated with AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine in England. Dev Med Child Neurol. DOI: 10.1111/dmcn.12522.
7. De la Herrán-Arita AK, Kornum BR, Mahlios J, et al. CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy. Sci Transl Med 2013; 5: 216ra176.