메뉴 건너뛰기




Volumn 96, Issue 6, 2014, Pages 1023-1035

miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin a type 1B receptor gene and finally reducing C/EBPα expression

Author keywords

Cell proliferation and cell cycle; Phosphorylation of Smad2 3; PU.1; TGF signaling pathway

Indexed keywords

ACTIVIN A; ACTIVIN TYPE 1B RECEPTOR; CCAAT ENHANCER BINDING PROTEIN ALPHA; MICRORNA; MICRORNA 199A 5P; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG; ACTIVIN RECEPTOR 1; ACVR1B PROTEIN, HUMAN; MIRN199 MICRORNA, HUMAN; ONCOPROTEIN; PROTO-ONCOGENE PROTEIN SPI-1; RETINOBLASTOMA PROTEIN; SMAD2 PROTEIN; SMAD2 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSACTIVATOR PROTEIN; TUMOR PROTEIN;

EID: 84914142033     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.1A0514-240R     Document Type: Article
Times cited : (36)

References (55)
  • 1
    • 78649410968 scopus 로고    scopus 로고
    • Networking erythropoiesis
    • Kerenyi, M. A., Orkin, S. H. (2010) Networking erythropoiesis. J. Exp. Med. 207, 2537-2541.
    • (2010) J. Exp. Med , vol.207 , pp. 2537-2541
    • Kerenyi, M.A.1    Orkin, S.H.2
  • 2
    • 79955411900 scopus 로고    scopus 로고
    • Small RNAs in early mammalian development: From gametes to gastrulation
    • Suh, N., Blelloch, R. (2011) Small RNAs in early mammalian development: from gametes to gastrulation. Development 138, 1653-1661.
    • (2011) Development , vol.138 , pp. 1653-1661
    • Suh, N.1    Blelloch, R.2
  • 3
    • 34547813709 scopus 로고    scopus 로고
    • MicroRNA-196 inhibits HOXB8 expression in myeloid differentiation of HL60 cells. Nucleic Acids Symp
    • Kawasaki, H., Taira, K. (2004) MicroRNA-196 inhibits HOXB8 expression in myeloid differentiation of HL60 cells. Nucleic Acids Symp. Ser. (Oxf). 48, 211-212.
    • (2004) Ser. (Oxf). , vol.48 , pp. 211-212
    • Kawasaki, H.1    Taira, K.2
  • 10
    • 84875228517 scopus 로고    scopus 로고
    • MicroRNA-376c impairs transforming growth factor-beta and nodal signaling to promote trophoblast cell proliferation and invasion
    • Fu, G., Ye, G., Nadeem, L., Ji, L., Manchanda, T., Wang, Y., Zhao, Y., Qiao, J., Wang, Y. L., Lye, S., Yang, B. B., Peng, C. (2013) MicroRNA-376c impairs transforming growth factor-beta and nodal signaling to promote trophoblast cell proliferation and invasion. Hypertension 61, 864-872.
    • (2013) Hypertension , vol.61 , pp. 864-872
    • Fu, G.1    Ye, G.2    Nadeem, L.3    Ji, L.4    Manchanda, T.5    Wang, Y.6    Zhao, Y.7    Qiao, J.8    Wang, Y.L.9    Lye, S.10    Yang, B.B.11    Peng, C.12
  • 12
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-beta signaling through Smads
    • Feng, X. H., Derynck, R. (2005) Specificity and versatility in TGF-beta signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693.
    • (2005) Annu. Rev. Cell Dev. Biol , vol.21 , pp. 659-693
    • Feng, X.H.1    Derynck, R.2
  • 14
    • 0026565263 scopus 로고
    • Evidence for the participation of endogenous activin A/erythroid differentiation factor in the regulation of erythropoiesis
    • Shiozaki, M., Sakai, R., Tabuchi, M., Nakamura, T., Sugino, K., Sugino, H., Eto, Y. (1992) Evidence for the participation of endogenous activin A/erythroid differentiation factor in the regulation of erythropoiesis. Proc. Natl. Acad. Sci. USA 89, 1553-1556.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1553-1556
    • Shiozaki, M.1    Sakai, R.2    Tabuchi, M.3    Nakamura, T.4    Sugino, K.5    Sugino, H.6    Eto, Y.7
  • 15
    • 38349146518 scopus 로고    scopus 로고
    • MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4
    • Wang, Q., Huang, Z., Xue, H., Jin, C., Ju, X. L., Han, J. D., Chen, Y. G. (2008) MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood 111, 588-595.
    • (2008) Blood , vol.111 , pp. 588-595
    • Wang, Q.1    Huang, Z.2    Xue, H.3    Jin, C.4    Ju, X.L.5    Han, J.D.6    Chen, Y.G.7
  • 16
    • 0028100573 scopus 로고
    • The growth response of Lin_Thy-1_hematopoietic progenitors to cytokines is determined by the balance between synergy of multiple stimulators and negative cooperation of multiple inhibitors. Exp
    • Jacobsen, S. E., Ruscetti, F. W., Ortiz, M., Gooya, J. M., Keller, J. R. (1994) The growth response of Lin_Thy-1_hematopoietic progenitors to cytokines is determined by the balance between synergy of multiple stimulators and negative cooperation of multiple inhibitors. Exp. Hematol. 22, 985-989.
    • (1994) Hematol , vol.22 , pp. 985-989
    • Jacobsen, S.E.1    Ruscetti, F.W.2    Ortiz, M.3    Gooya, J.M.4    Keller, J.R.5
  • 17
    • 0032191479 scopus 로고    scopus 로고
    • Growth-inhibitory effects of transforming growth factor-beta 1 on myeloid leukemia cell lines
    • Drexler, H. G., Meyer, C., Zaborski, M., Uphoff, C. C., Quentmeier, H. (1998) Growth-inhibitory effects of transforming growth factor-beta 1 on myeloid leukemia cell lines. Leuk. Res. 22, 927-938.
    • (1998) Leuk. Res , vol.22 , pp. 927-938
    • Drexler, H.G.1    Meyer, C.2    Zaborski, M.3    Uphoff, C.C.4    Quentmeier, H.5
  • 18
    • 67349240823 scopus 로고    scopus 로고
    • A new molecular network comprising PU. 1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells
    • De Marchis, M. L., Ballarino, M., Salvatori, B., Puzzolo, M. C., Bozzoni, I., Fatica, A. (2009) A new molecular network comprising PU. 1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells. Leukemia 23, 856-862.
    • (2009) Leukemia , vol.23 , pp. 856-862
    • De Marchis, M.L.1    Ballarino, M.2    Salvatori, B.3    Puzzolo, M.C.4    Bozzoni, I.5    Fatica, A.6
  • 19
    • 43749108643 scopus 로고    scopus 로고
    • A Smad-binding element in intron 1 participates in activin-dependent regulation of the follistatin gene
    • Blount, A. L., Vaughan, J. M., Vale, W. W., Bilezikjian, L. M. (2008) A Smad-binding element in intron 1 participates in activin-dependent regulation of the follistatin gene. J. Biol. Chem. 283, 7016-7026.
    • (2008) J. Biol. Chem , vol.283 , pp. 7016-7026
    • Blount, A.L.1    Vaughan, J.M.2    Vale, W.W.3    Bilezikjian, L.M.4
  • 20
    • 70449526719 scopus 로고    scopus 로고
    • Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
    • Giampieri, S., Manning, C., Hooper, S., Jones, L., Hill, C. S., Sahai, E. (2009) Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat. Cell Biol. 11, 1287-1296.
    • (2009) Nat. Cell Biol , vol.11 , pp. 1287-1296
    • Giampieri, S.1    Manning, C.2    Hooper, S.3    Jones, L.4    Hill, C.S.5    Sahai, E.6
  • 22
    • 77953806998 scopus 로고    scopus 로고
    • TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214
    • Yin, G., Chen, R., Alvero, A. B., Fu, H. H., Holmberg, J., Glackin, C., Rutherford, T., Mor, G. (2010) TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene 29, 3545-3553.
    • (2010) Oncogene , vol.29 , pp. 3545-3553
    • Yin, G.1    Chen, R.2    Alvero, A.B.3    Fu, H.H.4    Holmberg, J.5    Glackin, C.6    Rutherford, T.7    Mor, G.8
  • 23
    • 35348875999 scopus 로고    scopus 로고
    • Transcriptional control of granulocyte and monocyte development
    • Friedman, A. D. (2007) Transcriptional control of granulocyte and monocyte development. Oncogene 26, 6816-6828.
    • (2007) Oncogene , vol.26 , pp. 6816-6828
    • Friedman, A.D.1
  • 24
    • 84861409513 scopus 로고    scopus 로고
    • DNA binding regulates the self-association of the ETS domain of PU. 1 in a sequence-dependent manner
    • Poon, G. M. (2012) DNA binding regulates the self-association of the ETS domain of PU. 1 in a sequence-dependent manner. Biochemistry 51, 4096-4107.
    • (2012) Biochemistry , vol.51 , pp. 4096-4107
    • Poon, G.M.1
  • 25
    • 0034711307 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration
    • Bakin, A. V., Tomlinson, A. K., Bhowmick, N. A., Moses, H. L., Arteaga, C. L. (2000) Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. J. Biol. Chem. 275, 36803-36810.
    • (2000) J. Biol. Chem , vol.275 , pp. 36803-36810
    • Bakin, A.V.1    Tomlinson, A.K.2    Bhowmick, N.A.3    Moses, H.L.4    Arteaga, C.L.5
  • 26
    • 0036124281 scopus 로고    scopus 로고
    • Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27
    • Decker, T., Schneller, F., Hipp, S., Miething, C., Jahn, T., Duyster, J., Peschel, C. (2002) Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27. Leukemia 16, 327-334.
    • (2002) Leukemia , vol.16 , pp. 327-334
    • Decker, T.1    Schneller, F.2    Hipp, S.3    Miething, C.4    Jahn, T.5    Duyster, J.6    Peschel, C.7
  • 27
    • 34548838818 scopus 로고    scopus 로고
    • Pharmacologic inhibition of CDK4/6: Mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia
    • Wang, L., Wang, J., Blaser, B. W., Duchemin, A. M., Kusewitt, D. F., Liu, T., Caligiuri, M. A., Briesewitz, R. (2007) Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia. Blood 110, 2075-2083.
    • (2007) Blood , vol.110 , pp. 2075-2083
    • Wang, L.1    Wang, J.2    Blaser, B.W.3    Duchemin, A.M.4    Kusewitt, D.F.5    Liu, T.6    Caligiuri, M.A.7    Briesewitz, R.8
  • 28
    • 84856758666 scopus 로고    scopus 로고
    • MicroRNAs in acute leukemia: From biological players to clinical contributors
    • Schotte, D., Pieters, R., Den Boer, M. L. (2012) MicroRNAs in acute leukemia: from biological players to clinical contributors. Leukemia 26, 1-12.
    • (2012) Leukemia , vol.26 , pp. 1-12
    • Schotte, D.1    Pieters, R.2    Den Boer, M.L.3
  • 30
    • 84870052886 scopus 로고    scopus 로고
    • Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis
    • Pencheva, N., Tran, H., Buss, C., Huh, D., Drobnjak, M., Busam, K., Tavazoie, S. F. (2012) Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis. Cell 151, 1068-1082.
    • (2012) Cell , vol.151 , pp. 1068-1082
    • Pencheva, N.1    Tran, H.2    Buss, C.3    Huh, D.4    Drobnjak, M.5    Busam, K.6    Tavazoie, S.F.7
  • 31
    • 84870383614 scopus 로고    scopus 로고
    • The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway
    • Chan, Y. C., Roy, S., Huang, Y., Khanna, S., Sen, C. K. (2012) The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway. J. Biol. Chem. 287, 41032-41043.
    • (2012) J. Biol. Chem , vol.287 , pp. 41032-41043
    • Chan, Y.C.1    Roy, S.2    Huang, Y.3    Khanna, S.4    Sen, C.K.5
  • 32
    • 84863834241 scopus 로고    scopus 로고
    • Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. Biochem. Biophys. Res
    • Xu, N., Zhang, J., Shen, C., Luo, Y., Xia, L., Xue, F., Xia, Q. (2012) Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. Biochem. Biophys. Res. Commun. 423, 826-831.
    • (2012) Commun , vol.423 , pp. 826-831
    • Xu, N.1    Zhang, J.2    Shen, C.3    Luo, Y.4    Xia, L.5    Xue, F.6    Xia, Q.7
  • 33
    • 0024042026 scopus 로고
    • Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos
    • Thisse, B., Stoetzel, C., Gorostiza-Thisse, C., Perrin-Schmitt, F. (1988) Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos. EMBO J. 7, 2175-2183.
    • (1988) EMBO J , vol.7 , pp. 2175-2183
    • Thisse, B.1    Stoetzel, C.2    Gorostiza-Thisse, C.3    Perrin-Schmitt, F.4
  • 35
    • 84862489540 scopus 로고    scopus 로고
    • Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states
    • Pham, T. H., Benner, C., Lichtinger, M., Schwarzfischer, L., Hu, Y., Andreesen, R., Chen, W., Rehli, M. (2012) Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states. Blood 119, e161-e171.
    • (2012) Blood , vol.119 , pp. e161-e171
    • Pham, T.H.1    Benner, C.2    Lichtinger, M.3    Schwarzfischer, L.4    Hu, Y.5    Reesen, R.6    Chen, W.7    Rehli, M.8
  • 36
    • 42249090353 scopus 로고    scopus 로고
    • MiR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
    • Fujita, S., Ito, T., Mizutani, T., Minoguchi, S., Yamamichi, N., Sakurai, K., Iba, H. (2008) miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J. Mol. Biol. 378, 492-504.
    • (2008) J. Mol. Biol , vol.378 , pp. 492-504
    • Fujita, S.1    Ito, T.2    Mizutani, T.3    Minoguchi, S.4    Yamamichi, N.5    Sakurai, K.6    Iba, H.7
  • 38
    • 33745511278 scopus 로고    scopus 로고
    • A road map toward defining the role of Smad signaling in hematopoietic stem cells
    • Utsugisawa, T., Moody, J. L., Aspling, M., Nilsson, E., Carlsson, L., Karlsson, S. (2006) A road map toward defining the role of Smad signaling in hematopoietic stem cells. Stem Cells 24, 1128-1136.
    • (2006) Stem Cells , vol.24 , pp. 1128-1136
    • Utsugisawa, T.1    Moody, J.L.2    Aspling, M.3    Nilsson, E.4    Carlsson, L.5    Karlsson, S.6
  • 39
    • 79961130865 scopus 로고    scopus 로고
    • Combinatorial activin receptor-like kinase/Smad and basic fibroblast growth factor signals stimulate the differentiation of human embryonic stem cells into the cardiac lineage
    • Yook, J. Y., Kim, M. J., Son, M. J., Lee, S., Nam, Y., Han, Y. M., Cho, Y. S. (2011) Combinatorial activin receptor-like kinase/Smad and basic fibroblast growth factor signals stimulate the differentiation of human embryonic stem cells into the cardiac lineage. Stem Cells Dev. 20, 1479-1490.
    • (2011) Stem Cells Dev , vol.20 , pp. 1479-1490
    • Yook, J.Y.1    Kim, M.J.2    Son, M.J.3    Lee, S.4    Nam, Y.5    Han, Y.M.6    Cho, Y.S.7
  • 41
    • 0033515620 scopus 로고    scopus 로고
    • A Smad transcriptional corepressor
    • Wotton, D., Lo, R. S., Lee, S., Massague, J. (1999) A Smad transcriptional corepressor. Cell 97, 29-39.
    • (1999) Cell , vol.97 , pp. 29-39
    • Wotton, D.1    Lo, R.S.2    Lee, S.3    Massague, J.4
  • 42
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in cancer
    • Massague, J. (2008) TGFbeta in cancer. Cell 134, 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 43
    • 0033551666 scopus 로고    scopus 로고
    • CCAAT/enhancerbinding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development
    • Pan, Z., Hetherington, C. J., Zhang, D. E. (1999) CCAAT/enhancerbinding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J. Biol. Chem. 274, 23242-23248.
    • (1999) J. Biol. Chem , vol.274 , pp. 23242-23248
    • Pan, Z.1    Hetherington, C.J.2    Zhang, D.E.3
  • 44
    • 21644462493 scopus 로고    scopus 로고
    • Molecular stop signs: Regulation of cell-cycle arrest by C/EBP transcription factors
    • Johnson, P. F. (2005) Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors. J. Cell Sci. 118, 2545-2555.
    • (2005) J. Cell Sci , vol.118 , pp. 2545-2555
    • Johnson, P.F.1
  • 45
    • 34547133494 scopus 로고    scopus 로고
    • The C/EBP family of transcription factors: A paradigm for interaction between gene expression and proliferation control
    • Nerlov, C. (2007) The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends Cell Biol. 17, 318-324.
    • (2007) Trends Cell Biol , vol.17 , pp. 318-324
    • Nerlov, C.1
  • 46
    • 0029793902 scopus 로고    scopus 로고
    • PU. 1 (Spi-1) and C/EBP alpha regulate the granulocyte colonystimulating factor receptor promoter in myeloid cells
    • Smith, L. T., Hohaus, S., Gonzalez, D. A., Dziennis, S. E., Tenen, D. G. (1996) PU. 1 (Spi-1) and C/EBP alpha regulate the granulocyte colonystimulating factor receptor promoter in myeloid cells. Blood 88, 1234-1247.
    • (1996) Blood , vol.88 , pp. 1234-1247
    • Smith, L.T.1    Hohaus, S.2    Gonzalez, D.A.3    Dziennis, S.E.4    Tenen, D.G.5
  • 48
    • 0031029557 scopus 로고    scopus 로고
    • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice
    • Zhang, D. E., Zhang, P., Wang, N. D., Hetherington, C. J., Darlington, G. J., Tenen, D. G. (1997) Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc. Natl. Acad. Sci. USA 94, 569-574.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 569-574
    • Zhang, D.E.1    Zhang, P.2    Wang, N.D.3    Hetherington, C.J.4    Darlington, G.J.5    Tenen, D.G.6
  • 51
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer. Nat
    • Classon, M., Harlow, E. (2002) The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2, 910-917.
    • (2002) Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 52
    • 84876808719 scopus 로고    scopus 로고
    • Molecular mechanisms underlying RB protein function
    • Dick, F. A., Rubin, S. M. (2013) Molecular mechanisms underlying RB protein function. Nat. Rev. Mol. Cell. Biol. 14, 297-306.
    • (2013) Nat. Rev. Mol. Cell. Biol , vol.14 , pp. 297-306
    • Dick, F.A.1    Rubin, S.M.2
  • 53
    • 0026537277 scopus 로고
    • The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F
    • Hiebert, S. W., Chellappan, S. P., Horowitz, J. M., Nevins, J. R. (1992) The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. 6, 177-185.
    • (1992) Genes Dev , vol.6 , pp. 177-185
    • Hiebert, S.W.1    Chellappan, S.P.2    Horowitz, J.M.3    Nevins, J.R.4
  • 54
    • 0032931991 scopus 로고    scopus 로고
    • Cumulative effect of phosphorylation of pRB on regulation of E2F activity
    • Brown, V. D., Phillips, R. A., Gallie, B. L. (1999) Cumulative effect of phosphorylation of pRB on regulation of E2F activity. Mol. Cell. Biol. 19, 3246-3256.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 3246-3256
    • Brown, V.D.1    Phillips, R.A.2    Gallie, B.L.3
  • 55
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan, M. B., Bartek, J. (2004) Cell-cycle checkpoints and cancer. Nature 432, 316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.