Prucalopride is no more effective than placebo for children with functional constipation

Gastroenterology

Volumn 147, Issue 6, 2014, Pages 1285-1295.e1

  Mugie, Suzanne M ^a   Korczowski, Bartosz ^b   Bodi, Piroska ^c   Green, Alexandra ^d   Kerstens, René ^e   Ausma, Jannie ^e   Ruth, Magnus ^e   Levine, Amy ^f   Benninga, Marc A ^a  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

^b UNIVERSITY OF RZESZÓW   (Poland)

^c Pándy Kálmán Hospital   (Hungary)

^d Shire Pharmaceuticals   (United Kingdom)

^e Movetis NV   (Belgium)

^f SHIRE   (United States)

Author keywords

5 HT4 Receptor; Clinical Trial; Pediatric; TEAEs

Indexed keywords

IBUPROFEN; MACROGOL 4000; PARACETAMOL; PLACEBO; PRUCALOPRIDE; BENZOFURAN DERIVATIVE; SEROTONIN 4 AGONIST;

6 POINT SCALE; ABDOMINAL PAIN; ADOLESCENT; ANORECTAL DISEASE; ANXIETY; APPENDICITIS; ARTICLE; BRISTOL STOOL SCALE; BRONCHITIS; CHILD; CHILD REARING; CHILDHOOD DISEASE; CONSTIPATION; CONTROLLED STUDY; CONTUSION; COUGHING; DIARRHEA; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ELECTROCARDIOGRAM; FACES PAIN SCALE; FAINTNESS; FECES INCONTINENCE; FEMALE; FEVER; FUNCTIONAL CONSTIPATION; GLOBAL ASSESSMENT OF FUNCTIONING; HEADACHE; HUMAN; INFANT; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MULTICENTER STUDY; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NAUSEA; OPEN STUDY; PATIENT COMPLIANCE; PHARYNGITIS; PHASE 3 CLINICAL TRIAL; PNEUMONIA; PR INTERVAL; PROCTALGIA; PULSE RATE; QRS COMPLEX; QT INTERVAL; QT PROLONGATION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; ROME III CRITERIA; SIDE EFFECT; TABLET; TREATMENT DURATION; TREATMENT RESPONSE; UPPER RESPIRATORY TRACT INFECTION; VIRUS INFECTION; VOMITING; CLINICAL TRIAL; DEFECATION; DRUG EFFECTS; FECAL IMPACTION; PRESCHOOL CHILD; TREATMENT FAILURE;

ADOLESCENT; BENZOFURANS; CHILD; CHILD, PRESCHOOL; CONSTIPATION; DEFECATION; DOUBLE-BLIND METHOD; FECAL IMPACTION; FEMALE; HUMANS; INFANT; MALE; SEROTONIN 5-HT4 RECEPTOR AGONISTS; TREATMENT FAILURE;

EID: 84913534669     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.09.005     Document Type: Article

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