Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge

American Journal of Pathology

Volumn 184, Issue 12, 2014, Pages 3205-3216

  Hutt, Julie A ^a,b   Lovchik, Julie A ^b   Drysdale, Melissa ^b   Sherwood, Robert L ^a   Brasel, Trevor ^a,c   Lipscomb, Mary F ^b,d   Lyons, C Rick ^b,d  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TOXIN; ANTHRAX TOXIN; BACTERIAL ANTIGEN; BACTERIAL TOXIN; BACTERIUM ANTIBODY; VIRULENCE FACTOR;

ADULT; AMES TEST; ANIMAL EXPERIMENT; ANTHRAX; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BACTEREMIA; BACTERIAL LOAD; BACTERIAL SPORE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BRONCHOSCOPY; CONTROLLED STUDY; DELETION MUTANT; EDEMA; FEMALE; LETHAL GENE; MACACA FASCICULARIS; MALE; NONHUMAN; ANIMAL; BACILLUS ANTHRACIS; BLOOD; LUNG; MACACA; METABOLISM; MICROBIOLOGY; PATHOGENICITY; RESPIRATORY TRACT INFECTION; VIRULENCE;

ANIMALS; ANTHRAX; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; FEMALE; LUNG; MACACA; MALE; RESPIRATORY TRACT INFECTIONS; SPORES, BACTERIAL; VIRULENCE; VIRULENCE FACTORS;

EID: 84913534154     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.08.008     Document Type: Article

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