Efficacy of tigecycline, polymyxin, gentamicin, meropenem and associations in experimental Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae non-lethal sepsis

Brazilian Journal of Infectious Diseases

Volumn 18, Issue 5, 2014, Pages 574-575

  Toledo, Paula Virginia Michelon ^a,b   Tuon, Felipe Francisco ^a,b   Arend, Lavinia ^c   Aranha Junior, Ayrton Alves ^a,b  

^a STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c Bacteriology Section   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN; MEROPENEM; POLYMYXIN B; TIGECYCLINE; BACTERIAL PROTEIN; BETA LACTAMASE; CARBAPENEMASE; MINOCYCLINE; POLYMYXIN; THIENAMYCIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; BACTERIUM CULTURE; BLOOD CULTURE; CARBAPENEMASE PRODUCING KLEBSIELLA PNEUMONIAE; COLONY FORMING UNIT; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFICACY; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING KLEBSIELLA PNEUMONIAE; INOCULATION; KLEBSIELLA PNEUMONIAE INFECTION; LETTER; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; MOUSE; MURINE MODEL; NONHUMAN; PERITONEAL CULTURE; SEPSIS; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; DRUG COMBINATION; ENZYMOLOGY; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIOLOGY; PROCEDURES; RAT;

ANIMALS; BACTERIAL PROTEINS; BETA-LACTAMASES; DRUG THERAPY, COMBINATION; GENTAMICINS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MINOCYCLINE; POLYMYXINS; RATS; SEPSIS; THIENAMYCINS;

EID: 84912572846     PISSN: 14138670     EISSN: 16784391     Source Type: Journal    
DOI: 10.1016/j.bjid.2014.05.003     Document Type: Letter

References (2)

1. Lee G.C., Burgess D.S. Treatment of Klebsiella pneumoniae carbapenemase (KPC) infections: a review of published case series and case reports. Ann Clin Microbiol Antimicrob 2012, 11:32.
2. Pournarasa S., Vrioni G., Neou E., et al. Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time-kill assay. Int J Antimicrob Agents 2011, 37:244-247.