Immunohistochemical detection of ARID1A in colorectal carcinoma: Loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage

Human Pathology

Volumn 45, Issue 12, 2014, Pages 2430-2436

  Ye, Jiqing ^a   Zhou, Yi ^a   Weiser, Martin R ^a   Gönen, Mithat ^a   Zhang, Liying ^a   Samdani, Tushar ^a   Bacares, Ruben ^a   Delair, Deborah ^a   Ivelja, Sinisa ^a   Vakiani, Efsevia ^a   Klimstra, David S ^a   Soslow, Robert A ^a   Shia, Jinru ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Colon cancer; Immunohistochemistry; Microsatellite instability; MLH1 and PMS2; MLH1 methylation

Indexed keywords

ADENOSINE TRIPHOSPHATE; AT RICH INTERACTIVE DOMAIN CONTAINING PROTEIN 1A; UNCLASSIFIED DRUG; ARID1A PROTEIN, HUMAN; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; CANCER STAGING; COLORECTAL CARCINOMA; DISTANT METASTASIS; FEMALE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MEDULLARY CARCINOMA; MICROSATELLITE INSTABILITY; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION; SENESCENCE; TISSUE MICROARRAY; TUMOR DIFFERENTIATION; ADOLESCENT; AGED; COLORECTAL TUMOR; DNA METHYLATION; GENETICS; METABOLISM; MIDDLE AGED; MISMATCH REPAIR; PATHOLOGY; PILOT STUDY; VERY ELDERLY; YOUNG ADULT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, MEDULLARY; COLORECTAL NEOPLASMS; DNA METHYLATION; DNA MISMATCH REPAIR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; NEOPLASM STAGING; NUCLEAR PROTEINS; PILOT PROJECTS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84912528504     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.08.007     Document Type: Article

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