In situ investigation of mammalian inorganic polyphosphate localization using novel selective fluorescent probes JC-D7 and JC-D8

ACS Chemical Biology

Volumn 9, Issue 9, 2014, Pages 2101-2110

  Angelova, Plamena R ^c   Agrawalla, Bikram Keshari ^b   Elustondo, Pia A ^a   Gordon, Jacob ^a   Shiba, Toshikazu ^d   Abramov, Andrey Y ^c   Chang, Young Tae ^b   Pavlov, Evgeny V ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Regenetiss Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; FLUORESCENT DYE; JC D7; JC D8; POLYPHOSPHATE; RNA; UNCLASSIFIED DRUG; BENZIMIDAZOLE DERIVATIVE; DIMETHYL SULFOXIDE; INDOLE DERIVATIVE; JC-D7 COMPOUND; JC-D8 COMPOUND; LRRK2 PROTEIN, MOUSE; NAPHTHALENE DERIVATIVE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PTEN-INDUCED PUTATIVE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IN VITRO STUDY; LYSOSOME; MITOCHONDRION; MOUSE; NONHUMAN; PARKINSON DISEASE; ANIMAL; ASTROCYTE; BRAIN; C57BL MOUSE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOLECULAR IMAGING; PROCEDURES; RAT; REPRODUCIBILITY;

MAMMALIA;

ANIMALS; ASTROCYTES; BENZIMIDAZOLES; BRAIN; CELLS, CULTURED; DIMETHYL SULFOXIDE; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; FLUORESCENT DYES; HUMANS; INDOLES; LYSOSOMES; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR IMAGING; MOLECULAR STRUCTURE; NAPHTHALENES; PARKINSON DISEASE; POLYPHOSPHATES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; REPRODUCIBILITY OF RESULTS;

EID: 84912521626     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb5000696     Document Type: Article

References (31)

1. Kornberg, A., Rao, N. N., and ult-Riche, D. (1999) Inorganic polyphosphate: A molecule of many functions. Annu. Rev. Biochem. 68, 89-125.
2. Kulaev, I., Vagabov, V., and Kulakovskaya, T. (1999) New aspects of inorganic polyphosphate metabolism and function. J. Biosci. Bioeng. 88, 111-129.
3. Kumble, K. D., and Kornberg, A. (1995) Inorganic polyphosphate in mammalian cells and tissues. J. Biol. Chem. 270, 5818-5822.
4. Pavlov, E., Aschar-Sobbi, R., Campanella, M., Turner, R. J., Gomez-Garcia, M. R., and Abramov, A. Y. (2010) Inorganic polyphosphate and energy metabolism in mammalian cells. J. Biol. Chem. 285, 9420-9428.
5. Moreno-Sanchez, D., Hernandez-Ruiz, L., Ruiz, F. A., and Docampo, R. (2012) Polyphosphate is a novel pro-inflammatory regulator of mast cells and is located in acidocalcisomes. J. Biol. Chem. 287, 28435-28444.
6. Smith, S. A., Mutch, N. J., Baskar, D., Rohloff, P., Docampo, R., and Morrissey, J. H. (2006) Polyphosphate modulates blood coagulation and fibrinolysis. Proc. Natl. Acad. Sci. U.S.A. 103, 903-908.
7. Muller, F., Mutch, N. J., Schenk, W. A., Smith, S. A., Esterl, L., Spronk, H. M., Schmidbauer, S., Gahl, W. A., Morrissey, J. H., and Renne, T. (2009) Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell 139, 1143-1156.
8. Holmstrom, K. M., Marina, N., Baev, A. Y., Wood, N. W., Gourine, A. V., and Abramov, A. Y. (2013) Signalling properties of inorganic polyphosphate in the mammalian brain. Nat. Commun. 4, 1362.
9. Zakharian, E., Thyagarajan, B., French, R. J., Pavlov, E., and Rohacs, T. (2009) Inorganic polyphosphate modulates TRPM8 channels. PLoS One 4, e5404.
10. Wang, L., Fraley, C. D., Faridi, J., Kornberg, A., and Roth, R. A. (2003) Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells. Proc. Natl. Acad. Sci. U.S.A. 100, 11249-11254.
11. Abramov, A. Y., Fraley, C., Diao, C. T., Winkfein, R., Colicos, M. A., Duchen, M. R., French, R. J., and Pavlov, E. (2007) Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death. Proc. Natl. Acad. Sci. U.S.A. 104, 18091-18096.
12. Pavlov, E., Zakharian, E., Bladen, C., Diao, C. T., Grimbly, C., Reusch, R. N., and French, R. J. (2005) A large, voltage-dependent channel, isolated from mitochondria by water-free chloroform extraction. Biophys. J. 88, 2614-2625.
13. Kulakova, A. N., Hobbs, D., Smithen, M., Pavlov, E., Gilbert, J. A., Quinn, J. P., and McGrath, J. W. (2011) Direct quantification of inorganic polyphosphate in microbial cells using 4′-6-diamidino-2-phenylindole (DAPI). Environ. Sci. Technol. 45, 7799-7803.
14. Omelon, S., Georgiou, J., Henneman, Z. J., Wise, L. M., Sukhu, B., Hunt, T., Wynnyckyj, C., Holmyard, D., Bielecki, R., and Grynpas, M. D. (2009) Control of vertebrate skeletal mineralization by polyphosphates. PLoS One 4, e5634.
15. Aschar-Sobbi, R., Abramov, A. Y., Diao, C., Kargacin, M. E., Kargacin, G. J., French, R. J., and Pavlov, E. (2008) High sensitivity, quantitative measurements of polyphosphate using a new DAPI-Based approach. J. Fluoresc. 18, 859-866.
16. Diaz, J. M., and Ingall, E. D. (2010) Fluorometric quantification of natural inorganic polyphosphate. Environ. Sci. Technol. 44, 4665-4671.
17. Gomes, F. M., Ramos, I. B., Wendt, C., Girard-Dias, W., De, S. W., Machado, E. A., and Miranda, K. (2013) New insights into the in situ microscopic visualization and quantification of inorganic polyphosphate stores by 4′,6-diamidino-2-phenylindole (DAPI)-staining. Eur. J. Histochem. 57, e34.
18. Martin, P., and Van Mooy, B. A. (2013) Fluorometric quantification of polyphosphate in environmental plankton samples: Extraction protocols, matrix effects, and nucleic acid interference. Appl. Environ. Microbiol. 79, 273-281.
19. Feng, S., Kim, Y. K., Yang, S., and Chang, Y. T. (2010) Discovery of a green DNA probe for live-cell imaging. Chem. Commun. (Cambridge, U.K.) 46, 436-438.
20. Cervantes, S., Prudhomme, J., Carter, D., Gopi, K. G., Li, Q., Chang, Y. T., and Le Roch, K. G. (2009) High-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery. BMC Cell Biol. 10, 45.
21. Wang, S., and Chang, Y. T. (2008) Discovery of heparin chemosensors through diversity oriented fluorescence library approach. Chem. Commun. (Cambridge, U.K.), 1173-1175.
22. Wang, S., and Chang, Y. T. (2006) Combinatorial synthesis of benzimidazolium dyes and its diversity directed application toward GTP-selective fluorescent chemosensors. J. Am. Chem. Soc. 128, 10380-10381.
23. Ahn, Y. H., Lee, J. S., and Chang, Y. T. (2007) Combinatorial rosamine library and application to in vivo glutathione probe. J. Am. Chem. Soc. 129, 4510-4511.
24. Vendrell, M., Zhai, D., Er, J. C., and Chang, Y. T. (2012) Combinatorial strategies in fluorescent probe development. Chem. Rev. (Washington, DC, U.S.) 112, 4391-4420.
25. Pavlov, E., Aschar-Sobbi, R., Campanella, M., Turner, R. J., Gomez-Garcia, M. R., and Abramov, A. Y. (2010) Inorganic polyphosphate and energy metabolism in mammalian cells. J. Biol. Chem. 285, 9420-8.
26. Pisoni, R. L., and Lindley, E. R. (1992) Incorporation of [32P]orthophosphate into long chains of inorganic polyphosphate within lysosomes of human fibroblasts. J. Biol. Chem. 267, 3626-3631.
27. Zhang, Z., Chen, G., Zhou, W., Song, A., Xu, T., Luo, Q., Wang, W., Gu, X. S., and Duan, S. (2007) Regulated ATP release from astrocytes through lysosome exocytosis. Nat. Cell Biol. 9, 945-953.
28. Burchell, V. S., Gandhi, S., Deas, E., Wood, N. W., Abramov, A. Y., and Plun-Favreau, H. (2010) Targeting mitochondrial dysfunction in neurodegenerative disease: Part II. Expert Opin. Ther. Targets 14, 497-511.
29. Burchell, V. S., Gandhi, S., Deas, E., Wood, N. W., Abramov, A. Y., and Plun-Favreau, H. (2010) Targeting mitochondrial dysfunction in neurodegenerative disease: Part I. Expert Opin. Ther. Targets 14, 369-385.
30. Smith, S. A., Choi, S. H., Collins, J. N., Travers, R. J., Cooley, B. C., and Morrissey, J. H. (2012) Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation. Blood 120, 5103-5110.
31. Angelova, P., and Muller, W. (2006) Oxidative modulation of the transient potassium current IA by intracellular arachidonic acid in rat CA1 pyramidal neurons. Eur. J. Neurosci. 23, 2375-2384.