Tirasemtiv amplifies skeletal muscle response to nerve activation in humans

Muscle and Nerve

Volumn 50, Issue 6, 2014, Pages 925-931

  Hansen, Richard ^a   Saikali, Khalil G ^a   Chou, Willis ^a   Russell, Alan J ^a   Chen, Michael M ^a   Vijayakumar, Vipin ^a   Stoltz, Randall R ^b   Baudry, Stephane ^c   Enoka, Roger M ^d   Morgans, David J ^a   Wolff, Andrew A ^a   Malik, Fady I ^a  

^a Cytokinetics Inc   (United States)

^b Cytokinetics ^*  (United States)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Fast skeletal muscle troponin activator; Force frequency relationship; Phase 1; Skeletal muscle; Tirasemtiv

Indexed keywords

CK-2017357; IMIDAZOLE DERIVATIVE; MUSCLE RELAXANT AGENT; PYRAZINE DERIVATIVE; TNNT3 PROTEIN, HUMAN; TROPONIN T;

ADOLESCENT; ADULT; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; ELECTROSTIMULATION; HUMAN; INNERVATION; MALE; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SKELETAL MUSCLE; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ELECTRIC STIMULATION; HUMANS; IMIDAZOLES; MALE; MIDDLE AGED; MUSCLE, SKELETAL; NEUROMUSCULAR AGENTS; PYRAZINES; TROPONIN T; YOUNG ADULT;

EID: 84912139531     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.24239     Document Type: Article

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