Inulin-based polymer coated SPIONs as potential drug delivery systems for targeted cancer therapy

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 3, 2014, Pages 695-705

  Scialabba, C ^a   Licciardi, M ^a   Mauro, N ^a   Rocco, F ^b   Ceruti, M ^b   Giammona, G ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Doxorubicin; Inulin copolymer; Magnetic targeting; Pegylated; SPIONs; Squalene

Indexed keywords

DOXORUBICIN; IMINE; INULIN; MAGNETITE; NANOCARRIER; POLYMER; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; MAGNETITE NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; HUMAN; HUMAN CELL; HYDRODYNAMICS; HYDROPHOBICITY; IN VITRO STUDY; MAGNETIC FIELD; MOLECULARLY TARGETED THERAPY; SURFACE PROPERTY; THERAPY EFFECT; ZETA POTENTIAL; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; HCT116 CELL LINE; INFRARED SPECTROSCOPY; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY;

ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; DRUG LIBERATION; HCT116 CELLS; HUMANS; INULIN; MAGNETITE NANOPARTICLES; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; PARTICLE SIZE; POLYMERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES;

EID: 84912127965     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.09.008     Document Type: Article

References (37)

1. M.Z. Ahmad, S. Akhter, G.K. Jain, M. Rahman, S.A. Pathan, F.J. Ahmad, and R.K. Khar Metallic nanoparticles: technology overview & drug delivery applications in oncology Expert Opin. Drug Deliv. 7 2010 927 942
2. F. Si-Shen, and S. Chien Chemotherapeutic engineering: application and further development of chemical engineering principles for chemotherapy of cancer and other diseases Chem. Eng. Sci. 58 2003 4087 4114
3. S. Braunstein, and L.J. Nakamura Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk Front. Oncol. 2013 3 73
4. E.S. Kawasaki, and A. Player Nanotechnology, nanomedicine, and the development of new, effective therapies for cancer Nanomed.: Nanotechnol. Biol. Med. 1 2005 101 109
5. A. Kamb Opinion: what's wrong with our cancer models? Nat. Rev. Drug Discov. 4 2005 161 165
6. M. Licciardi, C. Scialabba, C. Sardo, G. Cavallaro, and G. Giammona Amphiphilic inulin graft co-polymers as self-assembling micelles for doxorubicin delivery J. Mater. Chem. 2 2014 4262 4271
7. E.F. Craparo, G. Teresi, M. Licciardi, M.L. Bondi', and G. Cavallaro Novel composed galactosylated nanodevices containing a ribavirin prodrug as hepatic cell-targeted carriers for hcv treatment J. Biomed. Nanotechnol. 9 2013 1107 1122
8. D. Paolino, M. Licciardi, C. Celia, G. Giammona, M. Fresta, and G. Cavallaro Folate-targeted supramolecular vesicular aggregates as a new frontier for effective anticancer treatment in "in vivo" model Eur. J. Pharm. Biopharm. 82 2012 94 102
9. J. Huwyler, J. Drewe, and S. Krähenbühl Tumor targeting using liposomal antineoplastic drugs Int. J. Nanomed. 3 2008 21 29
10. W.H. Chiang, W.-C. Huang, C.-W. Chang, M.-Y. Shen, Z.-F. Shih, Y.-F. Huang, S.C. Lin, and H.C. Chiue Functionalized polymerosomes with outlayered polyelectrolyte gels for potential tumor-targeted delivery of multimodal therapies and MR imaging J. Control. Release 3 2013 280 288
11. Brannon-Peppas, and J.O. Blanchette Nanoparticle and targeted systems for cancer therapy Adv. Drug Deliv. Rev. 56 2004 1649 1659
12. P.C. Griffiths, N. Mauro, D.M. Murphy, E. Carter, S.C.W. Richardson, P. Dyer, and P. Ferruti Self-assembled PAA-based nanoparticles as potential gene and protein delivery systems Macromol. Biosci. 13 2013 641 649
13. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 2000 271 284
14. H. Maeda, T. Sawa, and T. Konno Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS J. Control. Release 74 2001 47 61
15. R.H. Kodama Magnetic nanoparticles J. Magn. Magn. Mater. 200 1999 359 372
16. L.W. Hamley Nanotechnology with soft materials Angew. Chem. 42 2003 1692 1712
17. J. Riemer, H.H. Hepken, H. Czerwinska, S.R. Robinson, and R. Dringen Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells Anal. Biochem. 331 2004 370 375
18. M. Licciardi, C. Scialabba, C. Fiorica, G. Cavallaro, G. Cassata, and G. Giammona Polymeric nanocarriers for magnetic targeted drug delivery: preparation, characterization, and in vitro and in vivo evaluation Mol. Pharmacol. 10 2013 4397 4407
19. M. Mahmoudi, S. Santc, B. Wang, S. Laurent, and T. Sen Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy Adv. Drug Deliv. Rev. 63 2011 24 46
20. L. Zhang, F. Gong, F. Zhang, J. Ma, P. Zhang, and J. Shen Targeted therapy for human hepatic carcinoma cells using folate-functionalized polymeric micelles loaded with superparamagnetic iron oxide and sorafenib in vitro Int. J. Nanomed. 8 2013 1517 1524
21. G.F. Li, J. Fan, R. Jiang, and Y. Gao Cross-linking the linear polymeric chains in the atrp synthesis of iron oxide/polystyrene core/shell nanoparticles Chem. Mater. 16 2010 1835 1837
22. S.R. Wan, Y. Zheng, Y. Liu, H. Yan, and K. Liu Fe3O4 nanoparticles coated with homopolymers of glycerol mono(meth)acrylate and their block copolymers J. Mater. Chem. 15 2005 3424 3430
23. M. van der Zee, J.H. Stoutjesdijk, P.A.A.W. van der Heijden, and D. de Wit Structure-biodegradation relationships of polymeric materials. 1. Effect of degree of oxidation on biodegradability of carbohydrate polymers J. Environ. Polym. Degrad. 3 1995 235 242
24. S. Kolida, and G.R. Gibson Prebiotic capacity of inulin-type fructans J. Nutr. 137 2007 2503S 2506S
25. G. Pitarresi, D. Triolo, M. Giorgi, C. Fiorica, F. Calascibetta, and G. Giammona Inulin-based hydrogel for oral delivery of flutamide: preparation, characterization, and in vivo release studies Macromol. Biosci. 12 2012 770 778
26. E.F. Craparo, G. Cavallaro, M.L. Bondi, D. Mandracchia, and G. Giammona Pegylated nanoparticles based on a polyaspartamide. Preparation, physico-chemical characterization, and intracellular uptake Biomacromolecules 7 2006 3083 3092
27. D. Mandracchia, G. Tripodo, A. Latrofa, and R. Dorati Amphiphilic inulin-d-rmalpha-tocopherol succinate (invite) bioconjugates for biomedical applications Carbohydr. Polym. 103 2014 46 54
28. F.S. Palumbo, G. Pitarresi, D. Mandracchia, G. Tripodo, and G. Giammona New graft copolymers of hyaluronic acid and polylactic acid: synthesis and characterization Carbohydr. Polym. 66 3 2006 379 385
29. J. Ren, P. Wang, F. Dong, Y. Feng, D. Peng, and Z. Guo Synthesis and antifungal properties of 6-amino-6-deoxyinulin, a kind of precursors for facile chemical modifications of inulin Carbohydr. Polym. 87 2012 1744 1748
30. J. Ren, J. Liu, F. Dong, and Z. Guo Synthesis and hydroxyl radicals scavenging activity of N-(aminoethyl)inulin Carbohydr. Polym. 85 2011 268 271
31. M. Ceruti, F. Rocco, F. Viola, G. Balliano, G. Grosa, F. Dosio, and L. Cattel Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase Eur. J. Med. Chem. 28 1993 675 682
32. L. Cattel, M. Ceruti, G. Balliano, F. Viola, G. Grosa, F. Rocco, and P. Brusa 2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors Lipids 30 1995 235 246
33. F. Viola, M. Ceruti, L. Cattel, P. Milla, K. Poralla, and G. Balliano Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase Lipids 35 2000 297 303
34. P. Couvreur, L.H. Reddy, B. Pili, C. Bourgaux, and M. Ollivon Discovery of new hexagonal supramolecular nanostructures formed by squalenoylation of an anticancer nucleoside analogue Small 4 2 2008 247 253
35. G. Pitarresi, F.S. Palumbo, A. Albanese, C. Fiorica, P. Picone, and G. Giammona Self-assembled amphiphilic hyaluronic acid graft copolymers for targeted release of antitumoral drug J. Drug Targeting 18 2010 264 276
36. F. Shen, S. Chu, A.K. Bence, B. Bailey, X. Xue, P.A. Erickson, M.H. Montrose, W.T. Beck, and L.C. Erickson Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells J. Pharmacol. Exp. Ther. 324 2008 95 102
37. V. Sundaresana, J.U. Menon, M. Rahimi, K.T. Nguyena, and A.S. Wadajkar Dual-responsive polymer-coated iron oxide nanoparticles for drug delivery and imaging applications Int. J. Pharm. 466 2014 1 7