Evaluating the individualized treatment of traditional Chinese medicine: A pilot study of N-of-1 trials

Evidence-based Complementary and Alternative Medicine

Volumn 2014, Issue , 2014, Pages

  Huang, Haiyin ^a   Yang, Peilan ^a   Xue, Jingjing ^a   Tang, Jie ^a   Ding, Liyu ^a   Ma, Ying ^a   Wang, Jie ^a   Guyatt, Gordon H ^b   Vanniyasingam, Thuva ^b   Zhang, Yuqing ^b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMBROXOL; ANTIBIOTIC AGENT; BRONCHOCONSTRICTING AGENT; HERBACEOUS AGENT; PRESCRIPTION DRUG;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BREATHING EXERCISE; BRONCHIECTASIS; CASE REPORT; CHINESE MEDICINE; CLINICAL EVALUATION; CLINICAL FEATURE; CLINICAL PRACTICE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE EXACERBATION; DRUG EFFICACY; DRUG PREFERENCE; DRUG SAFETY; DRUG WITHDRAWAL; EVIDENCE BASED MEDICINE; FEASIBILITY STUDY; FEMALE; GENERAL CONDITION IMPROVEMENT; HUMAN; INTERVENTION STUDY; MALE; MEDICATION COMPLIANCE; MIDDLE AGED; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PERSONALIZED MEDICINE; PILOT STUDY; PRESCRIPTION; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SPUTUM LEVEL; SYNDROME DELINEATION; VISUAL ANALOG SCALE;

EID: 84912099472     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2014/148730     Document Type: Article

References (24)

1. Guyatt G. H.; Keller J. L.; Jaeschke R.; The n-of-1 randomized controlled trial: clinical usefulness. Annals of Internal Medicine 1990 112 4 293 299
2. Jørgensen J. T.; New era of personalized medicine: a 10-year anniversary. Oncologist 2009 14 5 557 558 10.1634/theoncologist.2009-0047 2-s2.0-66349100804
3. Hu S. X.; Foster T.; Kieffaber A.; Pharmacogenomics and personalized medicine: mapping of future value creation. Biotechniques 2005 39 10 S1 S6 2-s2.0-56049128019
4. Huang H. Y.; Yang P. L.; Zhang Y. Q.; Xue J. J.; Xu M. H.; Potential value and feasibility of N-of-1 randomized controlled trials in research of traditional Chinese medicine. Shanghai Journal of Traditional Chinese Medicine 2012 46 8 3 8
5. Liu J. P.; Zhang M.; Yang M.; The application of the design of N-of-1 randomized controlled trials in research of traditional Chinese medicine. Chinese Journal of Information on Traditional Chinese Medicine 2002 9 6 66 68
6. Pasteur M. C.; Bilton D.; Hill A. T.; British thoracic society guideline for non-CF bronchiectasis. Thorax 2010 65 supplement 1 i1 i58 10.1136/thx.2010.136119 2-s2.0-77955283910
7. The writing group of consensus of the experts on the diagnosis and treatment of bronchiectasis. Consensus of the experts on the diagnosis and treatment of bronchiectasis. Zhonghua Jie He He Hu Xi Za Zhi 2013 36 8 563 566
8. Huang H. Y.; Yang P. L.; Tang J.; Long term effect of the treatment method of strengthening vital Qi, transforming Phlegm and clearing heat for 46 cases of bronchiectasis. Journal of Traditional Chinese Medicine 2012 53 10 848 852
9. Mei L.; He X.; Xiong Y.; Shi K.; Lin Y.; Hu C.; Study of antibacterial activities test in serum of Scutellaria Baicalensis Georgi. Journal of Medical Research 2009 38 1 102 103
10. Mi W.; Wang Z.-Q.; Qiu S.-C.; Du Z.-Z.; Liu X.-B.; The in vitro growth inhibitory effect of radix arnebiae lithospermi (RAL) on bacteria. Lishizhen Medicine and Materia Medica Research 2007 18 9 2217
11. Zhaosheng H.; Science of Chinese Materia Medica 2006 7th Beijing, China People's Medical Publishing House
12. The State Administration of Traditional Chinese Medicine, Criteria of Diagnosis and Therapeutic Effect of TCM Diseases 1994 Nanjing, China Nanjing University Press
13. Zhang H. Y.; Li X.; Ni W.; Chen F.; Shao C.; Chinese medical syndrome differentiation laws of bronchiectasis. Shanghai Journal of Traditional Chinese Medicine 2005 39 1 16 18
14. Lu L.; The comparative study of traditional and modern boil medicine methods. China Medicine and Pharmacy 2012 2 18 45 46
15. Guyatt G.; Sackett D.; Adachi J.; A clinician's guide for conduction randomized trials in individual patients. Canadian Medical Association Journal 1988 139 497 503
16. Thabane L.; Ma J.; Chu R.; Cheng J.; Ismaila A.; Rios L. P.; Robson R.; Thabane M.; Giangregorio L.; Goldsmith C. H.; A tutorial on pilot studies: the what, why and how. BMC Medical Research Methodology 2010 10, article 1 10.1186/1471-2288-10-1 2-s2.0-77249142355
17. Nonoyama M. L.; Brooks D.; Guyatt G. H.; Goldstein R. S.; Effect of oxygen on health quality of life in patients with chronic obstructive pulmonary disease with transient exertional hypoxemia. American Journal of Respiratory and Critical Care Medicine 2007 176 4 343 349 10.1164/rccm.200702-308OC 2-s2.0-34547960768
18. Wang H.; Chen J.; Shang, H.-C.; Exploration and practice of N-of-1 trial design in clinical research of TCM. Chinese Journal of Traditional Chinese Medicine 2008 33 3 229 232
19. Da-jun Y.; Wei-liang W.; Fang L.; Randomized controlled trials in individual patient of third stage of chronic kidney disease. Journal of Traditional Chinese Medicine 2012 53 3 222 224
20. Zhang X.; Huang L.-F.; Li X.; Randomized controlled trials in individual pantient of third stage of hypertension intracerebral hemorrhage. Journal of Zhejiang University of TCM 2012 36 8 871 886
21. Yuhong H.; Qian L.; Yu L.; An n-of-1 trial service in clinical practice: testing the effectiveness of Liuwei Dihuang decoction for Kidney-Yin deficiency syndrome. Evidence-Based Complementary and Alternative Medicine 2013 2013 7 827915 10.1155/2013/827915
22. Jiang Z.; Liu J.; Ge F.; Liu J.; Application and consideration of placebo in clinical trial researches of new traditional Chinese medicine. Clinical Trial Researches of New Traditional Chinese Medicine. Modern Chinese Medicine 2013 15 6 464 466
23. Xie Z. J.; Wen C. P.; Fan Y. S.; Discussion on quality control of randomized, double-blind and placebo controlled clinical trial of Chinese medicine. CJTCMP 2012 27 6 1479 1481
24. Xiao X. H.; Dan Y.; Cheng J.; Increasing dosage: a momentous proposition to improve therapeutic eficacy of traditional Chinese medicine. China Journal of Chinese Materia Medica 2008 33 3 229 232