메뉴 건너뛰기




Volumn 210, Issue 10, 2014, Pages 1519-1522

The sooner, the better: More evidence that early antiretroviral therapy lowers viral reservoirs in HIV-Infected Infants

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY; VIRUS RNA; ANTIRETROVIRUS AGENT;

EID: 84912078677     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu298     Document Type: Note
Times cited : (8)

References (34)
  • 3
    • 56749097184 scopus 로고    scopus 로고
    • Early antiretroviral therapy and mortality among HIV-infected infants
    • Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008; 359:2233-44.
    • (2008) N Engl J Med , vol.359 , pp. 2233-2244
    • Violari, A.1    Cotton, M.F.2    Gibb, D.M.3
  • 4
    • 0038640413 scopus 로고    scopus 로고
    • Maternal health factors and early pediatric antiretroviral therapy influence the rate of perinatal HIV-1 disease progression in children
    • Abrams EJ, Wiener J, Carter R, et al. Maternal health factors and early pediatric antiretroviral therapy influence the rate of perinatal HIV-1 disease progression in children. AIDS 2003; 17:867-77.
    • (2003) AIDS , vol.17 , pp. 867-877
    • Abrams, E.J.1    Wiener, J.2    Carter, R.3
  • 5
    • 63149144501 scopus 로고    scopus 로고
    • Effect of early antiretroviral therapy on the risk of AIDS/death in HIV-infected infants
    • Goetghebuer T, Haelterman E, Le Chenadec J, et al. Effect of early antiretroviral therapy on the risk of AIDS/death in HIV-infected infants. AIDS 2009; 23:597-604.
    • (2009) AIDS , vol.23 , pp. 597-604
    • Goetghebuer, T.1    Haelterman, E.2    Le Chenadec, J.3
  • 6
    • 80255139495 scopus 로고    scopus 로고
    • Guidelines for the use of antiretroviral agents in pediatric infection. Accessed 8 May 2014
    • Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children. Guidelines for the use of antiretroviral agents in pediatric infection. http://aidsinfo.nih.gov/contentfiles/lvguidelines/pediatricguidelines. pdf. Accessed 8 May 2014.
    • Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children
  • 7
    • 9144270766 scopus 로고    scopus 로고
    • Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
    • Persaud D, Siberry GK, Ahonkhai A, et al. Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads. J Virol 2004; 78:968-79.
    • (2004) J Virol , vol.78 , pp. 968-979
    • Persaud, D.1    Siberry, G.K.2    Ahonkhai, A.3
  • 8
    • 84887243970 scopus 로고    scopus 로고
    • Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: Results from the children with HIV early antiretroviral (CHER) randomised trial
    • Cotton MF, Violari A, Otwombe K, et al. Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial. Lancet 2013; 382:1555-63.
    • (2013) Lancet , vol.382 , pp. 1555-1563
    • Cotton, M.F.1    Violari, A.2    Otwombe, K.3
  • 9
    • 0032555117 scopus 로고    scopus 로고
    • Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
    • Chun TW, Engel D, Berrey MM, Shea T, Corey L, Fauci AS. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc Natl Acad Sci U S A 1998; 95:8869-73.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8869-8873
    • Chun, T.W.1    Engel, D.2    Berrey, M.M.3    Shea, T.4    Corey, L.5    Fauci, A.S.6
  • 10
    • 0038579210 scopus 로고    scopus 로고
    • Longterm follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, Kajdas J, Finzi D, et al. Longterm follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 2003; 9:727-8.
    • (2003) Nat Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3
  • 11
    • 60549090253 scopus 로고    scopus 로고
    • Longterm control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. Longterm control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009; 360:692-8.
    • (2009) N Engl J Med , vol.360 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3
  • 12
    • 84887028999 scopus 로고    scopus 로고
    • Absence of detectable HIV-1 viremia after treatment cessation in an infant
    • Persaud D, Gay H, Ziemniak C, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 2013; 369:1828-35.
    • (2013) N Engl J Med , vol.369 , pp. 1828-1835
    • Persaud, D.1    Gay, H.2    Ziemniak, C.3
  • 14
    • 0242550686 scopus 로고    scopus 로고
    • Lymphocyte subsets in healthy children from birth through 18 years of age: The Pediatric AIDS Clinical Trials Group P1009 study
    • ShearerWT, Rosenblatt HM, Gelman RS, et al. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol 2003; 112:973-80.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 973-980
    • Shearer, W.T.1    Rosenblatt, H.M.2    Gelman, R.S.3
  • 15
    • 84897553850 scopus 로고    scopus 로고
    • Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children
    • Ananworanich J, Puthanakit T, Suntarattiwong P, et al. Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children. AIDS 2014; 28:1015-20.
    • (2014) AIDS , vol.28 , pp. 1015-1020
    • Ananworanich, J.1    Puthanakit, T.2    Suntarattiwong, P.3
  • 16
    • 84911005930 scopus 로고    scopus 로고
    • HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment
    • Luzuriaga K, Tabak B, Garber M, et al. HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment. J Infect Dis 2014; 210: 1529-98.
    • (2014) J Infect Dis , vol.210 , pp. 1529-1598
    • Luzuriaga, K.1    Tabak, B.2    Garber, M.3
  • 18
    • 0036606456 scopus 로고    scopus 로고
    • Relationship between the size of the human immunodeficiency virus type 1 (HIV-1) reservoir in peripheral blood CD4+ T cells and CD4+:CD8+ T cell ratios in aviremic HIV-1- infected individuals receiving long-term highly active antiretroviral therapy
    • Chun TW, Justement JS, Pandya P, et al. Relationship between the size of the human immunodeficiency virus type 1 (HIV-1) reservoir in peripheral blood CD4+ T cells and CD4+:CD8+ T cell ratios in aviremic HIV-1- infected individuals receiving long-term highly active antiretroviral therapy. J Infect Dis 2002; 185:1672-6.
    • (2002) J Infect Dis , vol.185 , pp. 1672-1676
    • Chun, T.W.1    Justement, J.S.2    Pandya, P.3
  • 19
    • 84894035657 scopus 로고    scopus 로고
    • Factors associated with a low HIV reservoir in patients with prolonged suppressive antiretroviral therapy
    • Fourati S, Flandre P, Calin R, et al. Factors associated with a low HIV reservoir in patients with prolonged suppressive antiretroviral therapy. J Antimicrob Chemother 2014; 69:753-6.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 753-756
    • Fourati, S.1    Flandre, P.2    Calin, R.3
  • 20
    • 40549092339 scopus 로고    scopus 로고
    • Persistence of HIV in gut-Associated lymphoid tissue despite long-term antiretroviral therapy
    • Chun TW, Nickle DC, Justement JS, et al. Persistence of HIV in gut-Associated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis 2008; 197:714-20.
    • (2008) J Infect Dis , vol.197 , pp. 714-720
    • Chun, T.W.1    Nickle, D.C.2    Justement, J.S.3
  • 21
    • 78149417719 scopus 로고    scopus 로고
    • Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy
    • Yukl SA, Gianella S, Sinclair E, et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis 2010; 202:1553-61.
    • (2010) J Infect Dis , vol.202 , pp. 1553-1561
    • Yukl, S.A.1    Gianella, S.2    Sinclair, E.3
  • 23
    • 84885058930 scopus 로고    scopus 로고
    • Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size
    • Jain V, Hartogensis W, Bacchetti P, et al. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis 2013; 208:1202-11.
    • (2013) J Infect Dis , vol.208 , pp. 1202-1211
    • Jain, V.1    Hartogensis, W.2    Bacchetti, P.3
  • 24
    • 20244376915 scopus 로고    scopus 로고
    • Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1
    • Strain MC, Little SJ, Daar ES, et al. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis 2005; 191:1410-8.
    • (2005) J Infect Dis , vol.191 , pp. 1410-1418
    • Strain, M.C.1    Little, S.J.2    Daar, E.S.3
  • 25
    • 84911005050 scopus 로고    scopus 로고
    • Long-term antiretroviral treatment initiated in primary HIV-1 infection affects the size, composition and decay kinetics of the reservoir of HIV-1 infected CD4 T cells
    • In press
    • Buzon MJ, Pereyra F, Martin-Gayo E, et al. Long-term antiretroviral treatment initiated in primary HIV-1 infection affects the size, composition and decay kinetics of the reservoir of HIV-1 infected CD4 T cells. J Virol 2014. In press.
    • (2014) J Virol
    • Buzon, M.J.1    Pereyra, F.2    Martin-Gayo, E.3
  • 26
    • 84876411341 scopus 로고    scopus 로고
    • Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts
    • Hocqueloux L, Avettand-Fenoel V, Jacquot S, et al. Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. J Antimicrob Chemother 2013; 68:1169-78.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1169-1178
    • Hocqueloux, L.1    Avettand-Fenoel, V.2    Jacquot, S.3
  • 27
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 2003; 187:1534-43.
    • (2003) J Infect Dis , vol.187 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3
  • 28
    • 33745891216 scopus 로고    scopus 로고
    • Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: Results from ACTG 384
    • Gandhi RT, Spritzler J, Chan E, et al. Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384. J Acquir Immune Defic Syndr 2006; 42:426-34.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 426-434
    • Gandhi, R.T.1    Spritzler, J.2    Chan, E.3
  • 30
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 2013; 9:e1003211.
    • (2013) PLoS Pathog , vol.9 , pp. e1003211
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 31
    • 78549235738 scopus 로고    scopus 로고
    • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication
    • Chun TW, Justement JS, Murray D, et al. Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. AIDS 2010; 24: 2803-8.
    • (2010) AIDS , vol.24 , pp. 2803-2808
    • Chun, T.W.1    Justement, J.S.2    Murray, D.3
  • 32
    • 84877278315 scopus 로고    scopus 로고
    • Long-term reduction in peripheral blood HIV-1 Reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation
    • Henrich TJ, Hu Z, Li JZ, et al. Long-term reduction in peripheral blood HIV-1 Reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis 2013; 207:1694-702.
    • (2013) J Infect Dis , vol.207 , pp. 1694-1702
    • Henrich, T.J.1    Hu, Z.2    Li, J.Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.