Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial)

American Journal of Cardiology

Volumn 114, Issue 11, 2014, Pages 1713-1721

  Vaduganathan, Muthiah ^a   Greene, Stephen J ^b   Ambrosy, Andrew P ^c   Mentz, Robert J ^d   Subacius, Haris P ^b   Chioncel, Ovidiu ^e   Maggioni, Aldo P ^f   Swedberg, Karl ^g   Zannad, Faiez ^h   Konstam, Marvin A ⁱ   Senni, Michele ^j   Givertz, Michael M ^k   Butler, Javed ^l   Gheorghiade, Mihai ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e Institute of Emergency for Cardiovascular Diseases Prof CC Iliescu   (Romania)

^f ANMCO RESEARCH CENTER   (Italy)

^g UNIVERSITY OF GOTHENBURG   (Sweden)

^h UNIVERSITÉ DE LORRAINE   (France)

ⁱ TUFTS MEDICAL CENTER   (United States)

^j Azienda Ospedaliera Papa Giovanni XXIII   (Italy)

^k HARVARD MEDICAL SCHOOL   (United States)

^l EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; NATRIURETIC FACTOR; OXIPURINOL; PLACEBO; TOLVAPTAN; URIC ACID; URICOSURIC AGENT; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V2 RECEPTOR; XANTHINE OXIDASE INHIBITOR; BENZAZEPINE DERIVATIVE;

ADULT; AGED; ARTICLE; BLACK PERSON; CARDIOVASCULAR MORTALITY; CAUCASIAN; CHRONIC DISEASE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GLOMERULUS FILTRATION RATE; HAZARD RATIO; HEART EJECTION FRACTION; HEART FAILURE; HOSPITALIZATION; HUMAN; HYPERURICEMIA; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; META ANALYSIS (TOPIC); MORBIDITY; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; OUTCOMES RESEARCH; PROGNOSIS; RACE DIFFERENCE; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; URIC ACID BLOOD LEVEL; AFRICAN AMERICAN; AGE; BLOOD; BLOOD PRESSURE; DRUG THERAPY; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; KIDNEY FAILURE; MIDDLE AGED; PHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; SYSTOLE;

AFRICAN AMERICANS; AGE FACTORS; AGED; ANTIDIURETIC HORMONE RECEPTOR ANTAGONISTS; BENZAZEPINES; BLOOD PRESSURE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLOMERULAR FILTRATION RATE; HEART FAILURE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDES; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RENAL INSUFFICIENCY; RISK FACTORS; SEX FACTORS; STROKE VOLUME; SYSTOLE; TREATMENT OUTCOME; URIC ACID; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84912052219     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2014.09.008     Document Type: Article

References (30)

1. M. Gheorghiade, P.S. Pang, A.P. Ambrosy, G. Lan, P. Schmidt, G. Filippatos, M. Konstam, K. Swedberg, T. Cook, B. Traver, A. Maggioni, J. Burnett, L. Grinfeld, J. Udelson, and F. Zannad A comprehensive, longitudinal description of the in-hospital and post-discharge clinical, laboratory, and neurohormonal course of patients with heart failure who die or are re-hospitalized within 90 days: analysis from the EVEREST trial Heart Fail Rev 17 2012 485 509
2. D. Misra, Y. Zhu, Y. Zhang, and H.K. Choi The independent impact of congestive heart failure status and diuretic use on serum uric acid among men with a high cardiovascular risk profile: a prospective longitudinal study Semin Arthritis Rheum 41 2011 471 476
3. A.L. Alimonda, J. Nunez, E. Nunez, O. Husser, J. Sanchis, V. Bodi, G. Minana, R. Robles, L. Mainar, P. Merlos, H. Darmofal, and A. Llacer Hyperuricemia in acute heart failure. More than a simple spectator? Eur J Intern Med 20 2009 74 79
4. A. Cengel, S. Turkoglu, M. Turfan, and B. Boyaci Serum uric acid levels as a predictor of in-hospital death in patients hospitalized for decompensated heart failure Acta Cardiol 60 2005 489 492
5. S. Hamaguchi, T. Furumoto, M. Tsuchihashi-Makaya, K. Goto, D. Goto, T. Yokota, S. Kinugawa, H. Yokoshiki, A. Takeshita, H. Tsutsui Investigators J-C Hyperuricemia predicts adverse outcomes in patients with heart failure Int J Cardiol 151 2011 143 147
6. Q. Henry-Okafor, S.P. Collins, C.A. Jenkins, K.F. Miller, D.J. Maron, A.J. Naftilan, N. Weintraub, G.J. Fermann, J. McPherson, S. Menon, D.B. Sawyer, and A.B. Storrow Relationship between uric acid levels and diagnostic and prognostic outcomes in acute heart failure Open Biomark J 5 2012 9 15
7. F. Malek, P. Ostadal, J. Parenica, J. Jarkovsky, J. Vitovec, P. Widimsky, A. Linhart, M. Fedorco, Z. Coufal, R. Miklik, A. Kruger, D. Vondrakova, and J. Spinar Uric acid, allopurinol therapy, and mortality in patients with acute heart failure-results of the Acute HEart FAilure Database registry J Crit Care 27 2012 737.e11 737.e24
8. V. Novack, M. Pencina, D. Zahger, L. Fuchs, R. Nevzorov, A. Jotkowitz, and A. Porath Routine laboratory results and thirty day and one-year mortality risk following hospitalization with acute decompensated heart failure PLoS One 5 2010 e12184
9. H.S. Park, H. Kim, J.H. Sohn, H.W. Shin, Y.K. Cho, H.J. Yoon, C.W. Nam, S.H. Hur, Y.N. Kim, K.B. Kim, and H.J. Park Combination of uric acid and NT-ProBNP: a more useful prognostic marker for short-term clinical outcomes in patients with acute heart failure Korean J Intern Med 25 2010 253 259
10. D.A. Pascual-Figal, J.A. Hurtado-Martinez, B. Redondo, M.J. Antolinos, J.A. Ruiperez, and M. Valdes Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patients Eur J Heart Fail 9 2007 518 524
11. A. Wasserman, M. Shnell, B. Boursi, and H. Guzner-Gur Prognostic significance of serum uric acid in patients admitted to the Department of Medicine Am J Med Sci 339 2010 15 21
12. Y. Tian, Y. Chen, B. Deng, G. Liu, Z.G. Ji, Q.Z. Zhao, Y.Z. Zhen, Y.Q. Gao, L. Tian, L. Wang, L.S. Ji, G.P. Ma, K.S. Liu, and C. Liu Serum uric acid as an index of impaired renal function in congestive heart failure J Geriatr Cardiol 9 2012 137 142
13. J.W. Maynard, M.A. McAdams-Demarco, A. Law, L. Kao, A.C. Gelber, J. Coresh, and A.N. Baer Racial differences in gout incidence in a population-based cohort: Atherosclerosis Risk in Communities Study Am J Epidemiol 179 2014 576 583
14. J.G. Puig, A.D. Michan, M.L. Jimenez, C. Perez de Ayala, F.A. Mateos, C.F. Capitan, E. de Miguel, and J.B. Gijon Female gout. Clinical spectrum and uric acid metabolism Arch Intern Med 151 1991 726 732
15. M. Gheorghiade, M.A. Konstam, J.C. Burnett Jr., L. Grinfeld, A.P. Maggioni, K. Swedberg, J.E. Udelson, F. Zannad, T. Cook, J. Ouyang, C. Zimmer, and C. Orlandi Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials JAMA 297 2007 1332 1343
16. M. Gheorghiade, C. Orlandi, J.C. Burnett, D. Demets, L. Grinfeld, A. Maggioni, K. Swedberg, J.E. Udelson, F. Zannad, C. Zimmer, and M.A. Konstam Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the Efficacy of Vasopressin antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST) J Card Fail 11 2005 260 269
17. M.A. Konstam, M. Gheorghiade, J.C. Burnett Jr., L. Grinfeld, A.P. Maggioni, K. Swedberg, J.E. Udelson, F. Zannad, T. Cook, J. Ouyang, C. Zimmer, and C. Orlandi Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial JAMA 297 2007 1319 1331
18. H. Nacak, M. van Diepen, M.C. de Goeij, J.I. Rotmans, and F.W. Dekker Uric acid: association with rate of renal function decline and time until start of dialysis in incident pre-dialysis patients BMC Nephrol 15 2014 91
19. T. Sato, H. Yamauchi, S. Suzuki, A. Yoshihisa, T. Yamaki, K. Sugimoto, H. Kunii, K. Nakazato, H. Suzuki, S. Saitoh, and Y. Takeishi Distinct prognostic factors in patients with chronic heart failure and chronic kidney disease Int Heart J 54 2013 311 317
20. G.S. Filippatos, M.I. Ahmed, J.D. Gladden, M. Mujib, I.B. Aban, T.E. Love, P.W. Sanders, B. Pitt, S.D. Anker, and A. Ahmed Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data Eur Heart J 32 2011 712 720
21. H. Huang, B. Huang, Y. Li, Y. Huang, J. Li, H. Yao, X. Jing, J. Chen, and J. Wang Uric acid and risk of heart failure: a systematic review and meta-analysis Eur J Heart Fail 16 2014 15 24
22. F. Leyva, S.D. Anker, I.F. Godsland, M. Teixeira, P.G. Hellewell, W.J. Kox, P.A. Poole-Wilson, and A.J. Coats Uric acid in chronic heart failure: a marker of chronic inflammation Eur Heart J 19 1998 1814 1822
23. H. Alcaino, D. Greig, M. Chiong, H. Verdejo, R. Miranda, R. Concepcion, J.L. Vukasovic, G. Diaz-Araya, R. Mellado, L. Garcia, D. Salas, L. Gonzalez, I. Godoy, P. Castro, and S. Lavandero Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure Eur J Heart Fail 10 2008 646 651
24. F. Leyva, S. Anker, J.W. Swan, I.F. Godsland, C.S. Wingrove, T.P. Chua, J.C. Stevenson, and A.J. Coats Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure Eur Heart J 18 1997 858 865
25. H. Sakai, T. Tsutamoto, T. Tsutsui, T. Tanaka, C. Ishikawa, and M. Horie Serum level of uric acid, partly secreted from the failing heart, is a prognostic marker in patients with congestive heart failure Circ J 70 2006 1006 1011
26. K. Ogino, M. Kato, Y. Furuse, Y. Kinugasa, K. Ishida, S. Osaki, T. Kinugawa, O. Igawa, I. Hisatome, C. Shigemasa, S.D. Anker, and W. Doehner Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study Circ Heart Fail 3 2010 73 81
27. I. Gotsman, A. Keren, C. Lotan, and D.R. Zwas Changes in uric acid levels and allopurinol use in chronic heart failure: association with improved survival J Card Fail 18 2012 694 701
28. J.M. Hare, B. Mangal, J. Brown, C. Fisher Jr., R. Freudenberger, W.S. Colucci, D.L. Mann, P. Liu, M.M. Givertz, R.P. Schwarz Investigators O-C Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study J Am Coll Cardiol 51 2008 2301 2309
29. G. Savarese, C. Ferri, B. Trimarco, G. Rosano, S. Dellegrottaglie, T. Losco, L. Casaretti, C. D'Amore, F. Gambardella, M. Prastaro, G. Rengo, D. Leosco, and P. Perrone-Filardi Changes in serum uric acid levels and cardiovascular events: a meta-analysis Nutr Metab Cardiovasc Dis 23 2013 707 714
30. M.M. Givertz, D.L. Mann, K.L. Lee, J.C. Ibarra, E.J. Velazquez, A.F. Hernandez, A.M. Mascette, and E. Braunwald Xanthine oxidase inhibition for hyperuricemic heart failure patients: design and rationale of the EXACT-HF study Circ Heart Fail 6 2013 862 868