메뉴 건너뛰기




Volumn 16, Issue 12, 2014, Pages 1643-1655

Adipose-derived stem cells alleviate osteoporosis by enchancing osteogenesis and inhibiting adipogenesis in a rabbit model

Author keywords

Adipose derived stem cells; Alginate; Bone regeneration; Osteoporosis; Rabbit; Tissue engineering

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B;

EID: 84912047265     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.07.009     Document Type: Article
Times cited : (69)

References (47)
  • 1
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesis of osteoporosis: concepts, conflicts and prospects
    • Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts and prospects. JClin Invest 2005, 115:3318-3325.
    • (2005) JClin Invest , vol.115 , pp. 3318-3325
    • Raisz, L.G.1
  • 2
    • 84887618813 scopus 로고    scopus 로고
    • Osteoporosis-a current view of pharmacological prevention and treatment
    • Das S., Crockett J.C. Osteoporosis-a current view of pharmacological prevention and treatment. Drug Des Dev Ther 2013, 7:435-448.
    • (2013) Drug Des Dev Ther , vol.7 , pp. 435-448
    • Das, S.1    Crockett, J.C.2
  • 3
    • 0142182406 scopus 로고    scopus 로고
    • Absorptiometry and "osteoporosis": problems
    • Frost H.M. Absorptiometry and "osteoporosis": problems. JBone Miner Metab 2003, 21:255-260.
    • (2003) JBone Miner Metab , vol.21 , pp. 255-260
    • Frost, H.M.1
  • 4
    • 0030693262 scopus 로고    scopus 로고
    • Amorphometric comparison of trabecular structure of human ilium between microcomputed tomography and conventional histomorphometry
    • Uchiyama T., Tanizawa T., Muramatsu H., Endo N., Takahashi H.E., Hara T. Amorphometric comparison of trabecular structure of human ilium between microcomputed tomography and conventional histomorphometry. Calcif Tissue Int 1997, 61:493-498.
    • (1997) Calcif Tissue Int , vol.61 , pp. 493-498
    • Uchiyama, T.1    Tanizawa, T.2    Muramatsu, H.3    Endo, N.4    Takahashi, H.E.5    Hara, T.6
  • 5
    • 0036153106 scopus 로고    scopus 로고
    • Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells
    • Chen X.D., Shi S., Xu T., Robey P.G., Young M.F. Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells. JBone Miner Res 2002, 17:331-340.
    • (2002) JBone Miner Res , vol.17 , pp. 331-340
    • Chen, X.D.1    Shi, S.2    Xu, T.3    Robey, P.G.4    Young, M.F.5
  • 6
    • 0036724870 scopus 로고    scopus 로고
    • Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis
    • Verma S., Pajaratnam J.H., Denton J., Hoyland J.A., Byers R.J. Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. JClin Pathol 2002, 55:693-698.
    • (2002) JClin Pathol , vol.55 , pp. 693-698
    • Verma, S.1    Pajaratnam, J.H.2    Denton, J.3    Hoyland, J.A.4    Byers, R.J.5
  • 7
    • 79960554679 scopus 로고    scopus 로고
    • The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis
    • Liu H.Y., Wu A.T., Tsai C.Y., Chou K.R., Zeng R., Wang M.F., et al. The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. Biomaterials 2011, 32:6773-6780.
    • (2011) Biomaterials , vol.32 , pp. 6773-6780
    • Liu, H.Y.1    Wu, A.T.2    Tsai, C.Y.3    Chou, K.R.4    Zeng, R.5    Wang, M.F.6
  • 8
    • 0032805375 scopus 로고    scopus 로고
    • Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation
    • Nishida S., Endo N., Yamagiwa H., Tanizawa T., Takahashi H.E. Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation. JBone Miner Metab 1999, 17:171-177.
    • (1999) JBone Miner Metab , vol.17 , pp. 171-177
    • Nishida, S.1    Endo, N.2    Yamagiwa, H.3    Tanizawa, T.4    Takahashi, H.E.5
  • 9
    • 0034895190 scopus 로고    scopus 로고
    • Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges
    • Mueller S.M., Glowacki J. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. JCell Biochem 2001, 82:583-590.
    • (2001) JCell Biochem , vol.82 , pp. 583-590
    • Mueller, S.M.1    Glowacki, J.2
  • 10
    • 0347627149 scopus 로고    scopus 로고
    • Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
    • Stenderup K., Justesen J., Clausen C., Kassem M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 2003, 33:919-926.
    • (2003) Bone , vol.33 , pp. 919-926
    • Stenderup, K.1    Justesen, J.2    Clausen, C.3    Kassem, M.4
  • 11
    • 0344131893 scopus 로고    scopus 로고
    • Abnormal osteogenesis in osteoporotic patients is reflected by altered mesenchymal stem cells dynamics
    • Rodríguez J.P., Garat S., Gajardo H., Pino A.M., Seitz G. Abnormal osteogenesis in osteoporotic patients is reflected by altered mesenchymal stem cells dynamics. JCell Biochem 1999, 75:414-423.
    • (1999) JCell Biochem , vol.75 , pp. 414-423
    • Rodríguez, J.P.1    Garat, S.2    Gajardo, H.3    Pino, A.M.4    Seitz, G.5
  • 12
    • 0033785920 scopus 로고    scopus 로고
    • Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation
    • Rodríguez J.P., Montecinos L., Ríos S., Reyes P., Martínez J. Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation. JCell Biochem 2000, 79:557-565.
    • (2000) JCell Biochem , vol.79 , pp. 557-565
    • Rodríguez, J.P.1    Montecinos, L.2    Ríos, S.3    Reyes, P.4    Martínez, J.5
  • 13
    • 0034033355 scopus 로고    scopus 로고
    • Influence of mature adipocytes on osteoblast proliferation in human primary cocultures
    • Maurin A.C., Chavassieux P.M., Frappart L., Delmas P.D., Serre C.M., Meunier P.J. Influence of mature adipocytes on osteoblast proliferation in human primary cocultures. Bone 2000, 26:485-489.
    • (2000) Bone , vol.26 , pp. 485-489
    • Maurin, A.C.1    Chavassieux, P.M.2    Frappart, L.3    Delmas, P.D.4    Serre, C.M.5    Meunier, P.J.6
  • 14
    • 36849034568 scopus 로고    scopus 로고
    • PPAR-gamma regulates osteoclastogenesis in mice
    • Wan Y., Chong L.W., Evans R.M. PPAR-gamma regulates osteoclastogenesis in mice. Nat Med 2007, 13:1496-1503.
    • (2007) Nat Med , vol.13 , pp. 1496-1503
    • Wan, Y.1    Chong, L.W.2    Evans, R.M.3
  • 15
    • 66749124768 scopus 로고    scopus 로고
    • Adipose-derived stem cells for tissue repair and regeneration: ten years of research and a literature review
    • Mizuno H. Adipose-derived stem cells for tissue repair and regeneration: ten years of research and a literature review. JNippon Med Sch 2009, 76:56-66.
    • (2009) JNippon Med Sch , vol.76 , pp. 56-66
    • Mizuno, H.1
  • 16
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: implications for cell-based therapies
    • Zuk P.A., Zhu M., Mizuno H., Huang J., Futrell J.W., Katz A.J., et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001, 7:211-228.
    • (2001) Tissue Eng , vol.7 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3    Huang, J.4    Futrell, J.W.5    Katz, A.J.6
  • 18
    • 0242552104 scopus 로고    scopus 로고
    • Adipose-derived adult stem cells: isolation, characterization, and differentiation potential
    • Gimble J., Guilak F. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy 2003, 5:362-369.
    • (2003) Cytotherapy , vol.5 , pp. 362-369
    • Gimble, J.1    Guilak, F.2
  • 20
    • 2342586660 scopus 로고    scopus 로고
    • Adipose derived adult stromal cells heal critical-size mouse calvarial defects
    • Cowan C.M., Shi Y.Y., Aalami O.O., Chou Y.F., Mari C., Thomas R., et al. Adipose derived adult stromal cells heal critical-size mouse calvarial defects. Nat Biotechnol 2004, 22:560-567.
    • (2004) Nat Biotechnol , vol.22 , pp. 560-567
    • Cowan, C.M.1    Shi, Y.Y.2    Aalami, O.O.3    Chou, Y.F.4    Mari, C.5    Thomas, R.6
  • 21
    • 35349020566 scopus 로고    scopus 로고
    • Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model
    • Cui L., Liu B., Liu G., Zhang W., Cen L., Sun J., et al. Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model. Biomaterials 2007, 28:5477-5486.
    • (2007) Biomaterials , vol.28 , pp. 5477-5486
    • Cui, L.1    Liu, B.2    Liu, G.3    Zhang, W.4    Cen, L.5    Sun, J.6
  • 22
    • 77956218260 scopus 로고    scopus 로고
    • Human adipose derived stromal cells heal critical size mouse calvarial defects
    • Levi B., James A.W., Nelson E.R., Vistnes D., Wu B., Lee M., et al. Human adipose derived stromal cells heal critical size mouse calvarial defects. PLoS One 2010, 5:e11177.
    • (2010) PLoS One , vol.5 , pp. e11177
    • Levi, B.1    James, A.W.2    Nelson, E.R.3    Vistnes, D.4    Wu, B.5    Lee, M.6
  • 23
    • 84862896868 scopus 로고    scopus 로고
    • The effect of diminished osteogenic signals on reduced osteoporosis recovery in aged mice and the potential therapeutic use of adipose-derived stem cells
    • Liu H.Y., Chiou J.F., Wu A.T., Tsai C.Y., Leu J.D., Ting L.L., et al. The effect of diminished osteogenic signals on reduced osteoporosis recovery in aged mice and the potential therapeutic use of adipose-derived stem cells. Biomaterials 2012, 33:6105-6112.
    • (2012) Biomaterials , vol.33 , pp. 6105-6112
    • Liu, H.Y.1    Chiou, J.F.2    Wu, A.T.3    Tsai, C.Y.4    Leu, J.D.5    Ting, L.L.6
  • 24
    • 0027173887 scopus 로고
    • Animal models for the study of bone loss after cessation of ovarian function
    • Rodgers J.B., Monier-Faugere M.C., Malluche H. Animal models for the study of bone loss after cessation of ovarian function. Bone 1993, 14:369-377.
    • (1993) Bone , vol.14 , pp. 369-377
    • Rodgers, J.B.1    Monier-Faugere, M.C.2    Malluche, H.3
  • 25
    • 0028883653 scopus 로고
    • Assessing bone quality-animal models in preclinical osteoporosis research
    • Mosekilde L. Assessing bone quality-animal models in preclinical osteoporosis research. Bone 1995, 17(Suppl):343S-352S.
    • (1995) Bone , vol.17 , Issue.SUPPL , pp. 343S-352S
    • Mosekilde, L.1
  • 26
    • 0029984030 scopus 로고    scopus 로고
    • Hormone replacement therapy and cardiovascular disease: the rabbit model
    • Haarbo J. Hormone replacement therapy and cardiovascular disease: the rabbit model. Br J Obstet Gynecol 1996, 103 Suppl 13:49-51.
    • (1996) Br J Obstet Gynecol , pp. 49-51
    • Haarbo, J.1
  • 27
  • 28
    • 77649244537 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of osteogenesis of human umbilical cord blood-derived mesenchymal stem cells on partially demineralized bone matrix
    • Liu G., Li Y., Sun J., Zhou H., Zhang W., Cui L., et al. In vitro and in vivo evaluation of osteogenesis of human umbilical cord blood-derived mesenchymal stem cells on partially demineralized bone matrix. Tissue Eng Part A 2010, 16:971-982.
    • (2010) Tissue Eng Part A , vol.16 , pp. 971-982
    • Liu, G.1    Li, Y.2    Sun, J.3    Zhou, H.4    Zhang, W.5    Cui, L.6
  • 29
    • 84862892796 scopus 로고    scopus 로고
    • Ectopic bone regeneration by human bone marrow mononucleated cells, undifferentiated and osteogenically differentiated bone marrow mesenchymal stem cells in beta-tricalcium phosphate scaffolds
    • Ye X., Yin X., Yang D., Tan J., Liu G. Ectopic bone regeneration by human bone marrow mononucleated cells, undifferentiated and osteogenically differentiated bone marrow mesenchymal stem cells in beta-tricalcium phosphate scaffolds. Tissue Eng Part C 2012, 18:545-556.
    • (2012) Tissue Eng Part C , vol.18 , pp. 545-556
    • Ye, X.1    Yin, X.2    Yang, D.3    Tan, J.4    Liu, G.5
  • 30
    • 61849142793 scopus 로고    scopus 로고
    • In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells
    • Guo X., Park H., Liu G., Liu W., Cao Y., Tabata Y., et al. In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells. Biomaterials 2009, 30:2741-2752.
    • (2009) Biomaterials , vol.30 , pp. 2741-2752
    • Guo, X.1    Park, H.2    Liu, G.3    Liu, W.4    Cao, Y.5    Tabata, Y.6
  • 31
    • 33746736852 scopus 로고    scopus 로고
    • Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model
    • Wang Z., Goh J., Das De S., Ge Z., Ouyang H., Chong J.S., et al. Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model. Tissue Eng 2006, 12:1753-1761.
    • (2006) Tissue Eng , vol.12 , pp. 1753-1761
    • Wang, Z.1    Goh, J.2    Das De, S.3    Ge, Z.4    Ouyang, H.5    Chong, J.S.6
  • 32
    • 0019942628 scopus 로고
    • Changes in bone mineral density of the proximal femur and spine with aging: differences between the postmenopausal and senile OP syndromes
    • Riggs B.L., Wahner H.W., Seeman E., Offord K.P., Dunn W.L., Mazess R.B., et al. Changes in bone mineral density of the proximal femur and spine with aging: differences between the postmenopausal and senile OP syndromes. JClin Invest 1982, 70:716-723.
    • (1982) JClin Invest , vol.70 , pp. 716-723
    • Riggs, B.L.1    Wahner, H.W.2    Seeman, E.3    Offord, K.P.4    Dunn, W.L.5    Mazess, R.B.6
  • 33
    • 0033963919 scopus 로고    scopus 로고
    • Steroid hormone receptor expression and action in bone
    • Bland R. Steroid hormone receptor expression and action in bone. Clin Sci 2000, 98:217-240.
    • (2000) Clin Sci , vol.98 , pp. 217-240
    • Bland, R.1
  • 34
    • 0032896132 scopus 로고    scopus 로고
    • Estrogen increases 1,25-dihydroxyvitamin D receptors expression and bioresponse in the rat duodenal mucosa
    • Liel Y., Shany S., Smirnoff P., Schwartz B. Estrogen increases 1,25-dihydroxyvitamin D receptors expression and bioresponse in the rat duodenal mucosa. Endocrinology 1999, 140:280-285.
    • (1999) Endocrinology , vol.140 , pp. 280-285
    • Liel, Y.1    Shany, S.2    Smirnoff, P.3    Schwartz, B.4
  • 36
    • 78049427750 scopus 로고    scopus 로고
    • Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats
    • Ocarino Nde M., Boeloni J.N., Jorgetti V., Gomes D.A., Goes A.M., Serakides R. Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats. Connect Tissue Res 2010, 51:426-433.
    • (2010) Connect Tissue Res , vol.51 , pp. 426-433
    • Ocarino Nde, M.1    Boeloni, J.N.2    Jorgetti, V.3    Gomes, D.A.4    Goes, A.M.5    Serakides, R.6
  • 37
    • 84863136375 scopus 로고    scopus 로고
    • Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures
    • Chen H.T., Lee M.J., Chen C.H., Chuang S.C., Chang L.F., Ho M.L., et al. Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures. JCell Mol Med 2012, 16:582-593.
    • (2012) JCell Mol Med , vol.16 , pp. 582-593
    • Chen, H.T.1    Lee, M.J.2    Chen, C.H.3    Chuang, S.C.4    Chang, L.F.5    Ho, M.L.6
  • 38
    • 67349107689 scopus 로고    scopus 로고
    • The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells
    • Zhu M., Kohan E., Bradley J., Hedrick M., Benhaim P., Zuk P. The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells. JTissue Eng Regen Med 2009, 3:290-301.
    • (2009) JTissue Eng Regen Med , vol.3 , pp. 290-301
    • Zhu, M.1    Kohan, E.2    Bradley, J.3    Hedrick, M.4    Benhaim, P.5    Zuk, P.6
  • 39
    • 80053284870 scopus 로고    scopus 로고
    • Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function
    • Lee K., Kim H., Kim J.M., Kim J.R., Kim K.J., Kim Y.J., et al. Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function. JCell Mol Med 2011, 15:2082-2094.
    • (2011) JCell Mol Med , vol.15 , pp. 2082-2094
    • Lee, K.1    Kim, H.2    Kim, J.M.3    Kim, J.R.4    Kim, K.J.5    Kim, Y.J.6
  • 41
    • 0032749339 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts
    • Saadeh P.B., Mehrara B.J., Steinbrech D.S., Dudziak M.E., Greenwald J.A., Luchs J.S., et al. Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts. Am J Physiol 1999, 277:C628-C637.
    • (1999) Am J Physiol , vol.277 , pp. C628-C637
    • Saadeh, P.B.1    Mehrara, B.J.2    Steinbrech, D.S.3    Dudziak, M.E.4    Greenwald, J.A.5    Luchs, J.S.6
  • 42
    • 67650506105 scopus 로고    scopus 로고
    • TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
    • Tang Y., Wu X., Lei W., Pang L., Wan C., Shi Z., et al. TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 2009, 15:757-765.
    • (2009) Nat Med , vol.15 , pp. 757-765
    • Tang, Y.1    Wu, X.2    Lei, W.3    Pang, L.4    Wan, C.5    Shi, Z.6
  • 44
    • 0034194304 scopus 로고    scopus 로고
    • Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation
    • Choy L., Skillington J., Derynck R. Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation. JCell Biol 2000, 149:667-682.
    • (2000) JCell Biol , vol.149 , pp. 667-682
    • Choy, L.1    Skillington, J.2    Derynck, R.3
  • 45
    • 6944228180 scopus 로고    scopus 로고
    • Isoflavones extracted from sophorae fructus upregulate IGF-I and TGF-beta and inhibit osteoclastogenesis in rat bone marrow cells
    • Joo S.S., Won T.J., Kang H.C., Lee D.I. Isoflavones extracted from sophorae fructus upregulate IGF-I and TGF-beta and inhibit osteoclastogenesis in rat bone marrow cells. Arch Pharm Res 2004, 27:99-105.
    • (2004) Arch Pharm Res , vol.27 , pp. 99-105
    • Joo, S.S.1    Won, T.J.2    Kang, H.C.3    Lee, D.I.4
  • 46
    • 33747618270 scopus 로고    scopus 로고
    • Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling
    • Wan D.C., Shi Y.Y., Nacumuli R.P., Quarto N., Lyons K.M., Longaker M.T. Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling. Proc Natl Acad Sci U S A 2006, 103:12335-12340.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12335-12340
    • Wan, D.C.1    Shi, Y.Y.2    Nacumuli, R.P.3    Quarto, N.4    Lyons, K.M.5    Longaker, M.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.