Prehospital factors determining regional variation in thrombolytic therapy in acute ischemic stroke

International Journal of Stroke

Volumn 9, Issue A100, 2014, Pages 31-35

  Lahr, Maarten M H ^a   Vroomen, Patrick C A J ^a   Luijckx, Gert Jan ^a   van der Zee, Durk Jouke ^b   de Vos, Ronald ^a   Buskens, Erik ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Acute stroke; Organizational model; Prehospital; Regional variation; Thrombolysis

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

AGED; ARTICLE; BRAIN ISCHEMIA; CENTRALIZATION; CONTROLLED STUDY; DECENTRALIZATION; DIAGNOSTIC ERROR; EMERGENCY HEALTH SERVICE; FEMALE; FIBRINOLYTIC THERAPY; HEALTH CARE; HUMAN; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; OBSERVATIONAL STUDY; PATIENT REFERRAL; PATIENT TRANSPORT; ADULT; MIDDLE AGED; NONPARAMETRIC TEST; PROCEDURES; STROKE; THEORETICAL MODEL; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, THEORETICAL; NETHERLANDS; STATISTICS, NONPARAMETRIC; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME; TRIAGE; YOUNG ADULT;

EID: 84912041289     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/ijs.12236     Document Type: Article

References (23)

1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333:1581-1587.
2. Hacke W, Kaste M, Bluhmki E etal. Thrombolysis with alteplase 3 to 4·5 hours after acute ischemic stroke. N Engl J Med 2008; 359:1317-1329.
3. Wardlaw JM, Murray V, Berge E etal. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 2012; 379:2364-2372.
4. Allen NB, Kaltenbach L, Goldstein LB etal. Regional variation in recommended treatments for ischemic stroke and TIA: get with the guidelines-stroke 2003-2010. Stroke 2012; 43:1858-1864.
5. Gropen T, Magdon-Ismail Z, Day D, Melluzzo S, Schwamm LH, NECC Advisory Group. Regional implementation of the stroke systems of care model: recommendations of the northeast cerebrovascular consortium. Stroke 2009; 40:1793-1802.
6. Lahr MM, Luijckx GJ, Vroomen PC, van der Zee DJ, Buskens E. Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting. Stroke 2012; 43:1336-1340.
7. Verweij A, Sanderse C, Beer, de J. Zijn er in Nederland verschillen naar regio? In: Volksgezondheid Toekomst Verkenning, Nationaal Kompas Volksgezondheid. Bilthoven: RIVM, Nationaal Kompas Volksgezondheid\Bevolking. 2011. Available at http://www.nationaalkompas.nl (accessed 8 August 2012).
8. Uyttenboogaart M, Schrijvers EM, Vroomen PC, De Keyser J, Luijckx GJ. Routine thrombolysis with intravenous tissue plasminogen activator in acute ischaemic stroke patients aged 80 years or older: a single centre experience. Age Ageing 2007; 36:577-579.
9. Gomez-Choco M, Obach V, Urra X etal. The response to IV rt-PA in very old stroke patients. Eur J Neurol 2008; 15:253-256.
10. Wahlgren N, Ahmed N, Davalos A etal. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 2007; 369:275-282.
11. Dutch Institute for Healthcare Improvement CBO. Dutch Stroke Guideline 'Diagnostics, treatment, and care for stroke patients'. 2008. Available at http://www.cbo.nl/Downloads/218/rl_beroerte_09.pdf (accessed 8 August 2012).
12. Ambulancezorg Nederland. Landelijke standaard meldkamer ambulancezorg (LSMA-2). 2010; Available at http://www.ambulancezorg.nl/nederlands/pagina/1100/landelijke-standaard-meldkamer-ambulancezorg-lsma-html (accessed 8 August 2012).
13. Aries E, Bosker H, van Boven J, van Eenennaam J, van Elburg L. Landelijk protocol ambulancezorg. Herziene versie 7·2. 2011; Available at http://www.ambulancezorg.nl/nederlands/pagina/2037/lpa-7-2.html (accessed 8 August 2012).
14. Harbison J, Hossain O, Jenkinson D, Davis J, Louw SJ, Ford GA. Diagnostic accuracy of stroke referrals from primary care, emergency room physicians, and ambulance staff using the face arm speech test. Stroke 2003; 34:71-76.
15. Prabhakaran S, McNulty M, O'Neill K, Ouyang B. Intravenous thrombolysis for stroke increases over time at primary stroke centers. Stroke 2012; 43:875-877.
16. Tirschwell DL, Longstreth WT Jr, Becker KJ etal. Shortening the NIH Stroke scale for use in the prehospital setting. Stroke 2002; 33:2801-2806.
17. Adeoye O, Lindsell C, Broderick J etal. Emergency medical services use by stroke patients: a population-based study. Am J Emerg Med 2009; 27:141-145.
18. Rossnagel K, Jungehulsing GJ, Nolte CH etal. Out-of-hospital delays in patients with acute stroke. Ann Emerg Med 2004; 44:476-483.
19. Schwamm LH, Pancioli A, Acker JE III etal. Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Circulation 2005; 111:1078-1091.
20. Leira EC, Pary JK, Davis PH, Grimsman KJ, Adams HP Jr. Slow progressive acceptance of intravenous thrombolysis for patients with stroke by rural primary care physicians. Arch Neurol 2007; 64:518-521.
21. Grotta JC, Burgin WS, El-Mitwalli A etal. Intravenous tissue-type plasminogen activator therapy for ischemic stroke: Houston experience 1996 to 2000. Arch Neurol 2001; 58:2009-2013.
22. Bouckaert M, Lemmens R, Thijs V. Reducing prehospital delay in acute stroke. Nat Rev Neurol 2009; 5:477-483.
23. RIVM nationale atlas volksgezondheid. Available at http://www.zorgatlas.nl (accessed 6 February 2013).