Perioperative gabapentin and delirium following total knee arthroplasty: a post-hoc analysis of a double-blind randomized placebo-controlled trial

Canadian Journal of Anesthesia

Volumn 61, Issue 12, 2014, Pages 1136-1137

  Dighe, Krupa ^a   Clarke, Hance ^b   McCartney, Colin J ^b   Wong, Camilla L ^c,d  

^a Mackenzie Health   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; GABAPENTIN; MORPHINE; OPIATE; OXYCODONE; PLACEBO; 4 AMINOBUTYRIC ACID; AMINE; ANALGESIC AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE;

ADULT; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIRIUM; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; FEMALE; FEMORAL NERVE; HOSPITAL INFECTION; HUMAN; INSTITUTIONALIZATION; LETTER; MAJOR CLINICAL STUDY; MALE; MORTALITY; NERVE BLOCK; PAIN SEVERITY; PATIENT CONTROLLED ANALGESIA; PERIOPERATIVE PERIOD; POST HOC ANALYSIS; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; REHABILITATION; RISK FACTOR; SCIATIC NERVE; SPINAL ANESTHESIA; TOTAL KNEE REPLACEMENT; AGED; KNEE ARTHROPLASTY; MIDDLE AGED; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS;

AGED; AMINES; ANALGESICS; ARTHROPLASTY, REPLACEMENT, KNEE; CYCLOHEXANECARBOXYLIC ACIDS; DELIRIUM; DOUBLE-BLIND METHOD; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS;

EID: 84912021338     PISSN: 0832610X     EISSN: 14968975     Source Type: Journal    
DOI: 10.1007/s12630-014-0235-5     Document Type: Letter

References (5)

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3. Clarke HA, Katz J, McCartney CJ, et al. Perioperative gabapentin reduces 24 h opioid consumption and improves in-hospital rehabilitation but not post-discharge outcomes after total knee arthroplasty with peripheral nerve block. Br J Anaesth 2014; DOI: 10.1093/bja/aeu202.
4. Inouye SK, Leo-Summers L, Zhang Y, et al. A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method. J Am Geriatr Soc 2005; 53: 312-8.
5. Leung JM, Sands LP, Rico M, et al. Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. Neurology 2006; 67: 1251-3.