Preferential adherence to antiretroviral therapy over tuberculosis treatment: A qualitative study of drug-resistant TB/HIV co-infected patients in South Africa

Global Public Health

Volumn 9, Issue 9, 2014, Pages 1107-1116

  Daftary, Amrita ^a,b   Padayatchi, Nesri ^b   O'Donnell, Max ^a,b,c  

^a Department of Medicine   (United States)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

^c Department of Medicine   (United States)

Author keywords

adherence; co infection; drug resistant tuberculosis; HIV AIDS; qualitative methods

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; TUBERCULOSTATIC AGENT;

ADULT; ANTIRETROVIRAL THERAPY; ANTIVIRAL THERAPY; ARTICLE; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; FEMALE; HEALTH CARE PERSONNEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MIXED INFECTION; OBSERVATIONAL STUDY; PATIENT COMPLIANCE; PATIENT EDUCATION; PATIENT PARTICIPATION; QUALITATIVE ANALYSIS; QUALITATIVE RESEARCH; RESPONSIBILITY; SOCIAL ISOLATION; THEMATIC ANALYSIS; TREATMENT OUTCOME; ADOLESCENT; COMPLICATION; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS; HIV INFECTIONS; INFORMATION PROCESSING; MIDDLE AGED; PSYCHOLOGY; SOUTH AFRICA;

ADOLESCENT; ADULT; ANTI-HIV AGENTS; ANTITUBERCULAR AGENTS; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS; FEMALE; FOCUS GROUPS; HIV INFECTIONS; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; QUALITATIVE RESEARCH; SOUTH AFRICA;

EID: 84912010056     PISSN: 17441692     EISSN: 17441706     Source Type: Journal    
DOI: 10.1080/17441692.2014.934266     Document Type: Article

References (17)

1. Abdool Karim, S. S., Churchyard, G. J., Abdool Karim, Q., & Lawn, S. D. (2009). HIV infection and tuberculosis in South Africa: An urgent need to escalate the public health response. The Lancet, 374, 921–933. doi:10.1016/S0140-6736(09)60916-8
2. Brust, J. C., Gandhi, N. R., Carrara, H., Osburn, G., & Padayatchi, N. (2010). High treatment failure and default rates for patients with multidrug-resistant tuberculosis in KwaZulu-Natal, South Africa, 2000–2003. The International Journal of Tuberculosis and Lung Disease, 14, 413–419. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005763/
3. Brust, J. C., Shah, N. S., van der Merwe, T. L., Bamber, S., Ning, Y., Heo, M., Gandhi, N. R. (2013). Adverse events in an integrated home-based treatment program for MDR-TB and HIV in KwaZulu-Natal, South Africa. Journal of Acquired Immune Deficiency Syndromes, 62, 436–440. doi:10.1097/QAI.0b013e31828175ed
4. Corless, I. B., Wantland, D., Bhengu, B., McInerney, P., Ncama, B., Nicholas, P. K., Davis, S. M. (2009). HIV and tuberculosis in Durban, South Africa: Adherence to two medication regimens. AIDS Care, 21, 1106–1113. doi:10.1080/09540120902729932
5. Dooley, K. E., Nuermberger, E. L., & Diacon, A. H. (2013). Pipeline of drugs for related diseases: Tuberculosis. Current Opinion in HIV and AIDS, 8, 579–585. doi:10.1097/COH.0000000000000009
6. Gandhi, N. R., Andrews, J. R., Brust, J. C., Montreuil, R., Weissman, D., Heo, M., Shah, N. S. (2012). Risk factors for mortality among MDR- and XDR-TB patients in a high HIV prevalence setting. The International Journal of Tuberculosis and Lung Disease, 16(1), 90–97. doi:10.5588/ijtld.11.0153
7. Gardner, E. M., Sharma, S., Peng, G., Hullsiek, K. H., Burman, W. J., Macarthur, R. D., Mannheimer, S. B. (2008). Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance. AIDS, 22(1), 75–82. doi:10.1097/QAD.0b013e3282f366ff
8. Lawn, S. D., Kranzer, K., & Wood, R. (2009). Antiretroviral therapy for control of the HIV-associated tuberculosis epidemic in resource-limited settings. Clinics in Chest Medicine, 30, 685–699. doi:10.1016/j.ccm.2009.08.010
9. Macq, J., Torfoss, T., & Getahun, H. (2007). Patient empowerment in tuberculosis control: Reflecting on past documented experiences. Tropical Medicine & International Health, 12, 873–885. doi:10.1111/j.1365-3156.2007.01858.x
10. Mishra, S. I., Gioia, D., Childress, S., Barnet, B., & Webster, R. L. (2011). Adherence to medication regimens among low-income patients with multiple comorbid chronic conditions. Health & Social Work, 36, 249–258. doi:10.1093/hsw/36.4.249
11. O'Donnell, M. R., Padayatchi, N., Kvasnovsky, C., Werner, L., Master, I., & Horsburgh, C. R., Jr. (2013). Treatment outcomes for extensively drug-resistant tuberculosis and HIV co-infection. Emerging Infectious Diseases, 19, 416–424. doi:10.3201/eid1903.120998
12. O'Donnell, M., Wolf, A., Werner, L., Horsburgh, C. R., & Padayatchi, N. (2014). Adherence in the treatment of patients with extensively drug-resistant tuberculosis and HIV in South Africa: A prospective cohort study. Journal of Acquired Immune Deficiency Syndromes, May 27. [Epub ahead of print] PubMed PMID: 24872138.
13. Pietersen, E., Ignatius, E., Streicher, E. M., Mastrapa, B., Padanilam, X., Pooran, A., Dheda, K. (2014). Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: A cohort study. The Lancet, 383, 1230–1239. doi:10.1016/S0140-6736(13)62675-6
14. Seale, C., Gobo, G., Gubrium, J. F., & Silverman, D. (2004). Qualitative research practice. Thousand Oaks, CA: Sage.
15. Stack, R. J., Elliott, R. A., Noyce, P. R., & Bundy, C. (2008). A qualitative exploration of multiple medicines beliefs in co-morbid diabetes and cardiovascular disease. Diabetic Medicine, 25, 1204–1210. doi:10.1111/j.1464-5491.2008.02561.x
16. WHO (World Health Organization). (2010). Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response. Geneva: Author.
17. Williams, A., & Manias, E. (2014). Exploring motivation and confidence in taking prescribed medicines in coexisting diseases: A qualitative study. Journal of Clinical Nursing, 23, 471–481. doi:10.1111/jocn.12171