Association between genetic variant in hsa-miR-146a gene and prostate cancer progression: evidence from Serbian population

Cancer Causes and Control

Volumn 25, Issue 11, 2014, Pages 1571-1575

  Nikolić, Zorana Z ^a   Savić Pavićević, Dušanka Lj ^a   Vukotić, Vinka D ^b   Tomović, Saša M ^c   Cerović, Snežana J ^d   Filipović, Nataša ^b   Romac, Stanka P ^a   Brajušković, Goran N ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b Clinical Center Dr Dragisa Misovic   (Serbia)

^c Emeritus of Cardiology   (Serbia)

^d UNIVERSITY OF DEFENCE   (Serbia)

Author keywords

Association study; microRNA; miR 146a; Prostate cancer; Single nucleotide polymorphism

Indexed keywords

MICRORNA 146A; PROSTATE SPECIFIC ANTIGEN; MICRORNA; MIRN146 MICRORNA, HUMAN;

AGED; ARTICLE; BLOOD SAMPLING; CANCER GROWTH; CANCER RISK; CANCER STAGING; CONTROLLED STUDY; DISTANT METASTASIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GLEASON SCORE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIR 146A GENE; ORAL BIOPSY; PROSTATE CANCER; SERBIAN (CITIZEN); SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; ALLELE; BLOOD; CANCER GRADING; CASE CONTROL STUDY; CAUCASIAN; DISEASE COURSE; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; MIDDLE AGED; PATHOLOGY; PROSTATIC NEOPLASMS; RISK; SERBIA;

ADULT; AGED; ALLELES; CASE-CONTROL STUDIES; DISEASE PROGRESSION; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM GRADING; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RISK; SERBIA;

EID: 84911953535     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-014-0452-9     Document Type: Article

References (19)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN. Int J Cancer 127(12):2893–2917
2. Alshalalfa M, Bader GD, Goldenberg A, Morris Q, Alhajj R (2012) Detecting microRNAs of high influence on protein functional interaction networks: a prostate cancer case study. BMC Syst Biol 6:112
3. Farazi TA, Hoell JI, Morozov P, Tuschl T (2013) MicroRNAs in human cancer. Adv Exp Med Biol 774:1–20
4. Shenouda SK, Alaahri SK (2009) MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev 28:369–378
5. Xu B, Feng NH, Li PC et al (2010) A functional polymorphism in pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo. Prostate 70(5):467–472
6. George GP, Gangwar R, Mandal RK, Sankhwar SN, Mittal RD (2011) Genetic variation in microRNA genes and prostate cancer risk in North Indian population. Mol Biol Rep 38(3):1609–1615
7. Medeiros RM, Morais A, Vasconcelos A et al (2002) Outcome in prostate cancer: association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7. Clin Cancer Res 8(11):3433–3437
8. Purcell S, Neale B, Todd-Brown K et al (2007) PLINK: a toolset for whole-genome association and population-based linkage analysis. Am J Hum Genet 81(3):559–575
9. Solé X, Guinó E, Valls J, Iniesta R, Moreno V (2006) SNPstats: a web tool for the analysis of association studies. Bioinformatics 22(15):1928–1929
10. Wigginton JE, Cutler DJ, Abecasis GR (2005) A note on exact tests of Hardy–Weinberg equilibrium. Am J Hum Genet 76(5):887–893
11. Jazdzewski K, Murray EL, Franssila K, Jarzab B, Schoenberg DR, de la Chapelle A (2008) Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci USA 105(20):7269–7274
12. Pastrello C, Polesel J, Della Puppa L, Viel A, Maestro R (2010) Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients. Carcinogenesis 31(12):2124–2126
13. Yue C, Wang M, Ding B et al (2011) Polymorphism of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population. Gynecol Oncol 122(1):33–37
14. Guo H, Wang K, Xiong G et al (2010) A functional varient in microRNA-146a is associated with risk of esophageal squamous cell carcinoma in Chinese Han. Fam Cancer 9(4):599–603
15. Xu T, Zhu Y, Wei QK et al (2008) A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 29(11):2126–2131
16. Zeng Y, Sun QM, Liu NN et al (2010) Correlation between pre-miR-146a C/G polymorphism and gastric cancer risk in Chinese population. World J Gastroenterol 16(28):3578–3583
17. Jazdzewski K, Liyanarachchi S, Swierniak M et al (2009) Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proc Natl Acad Sci USA 106(5):1502–1505
18. Lin SL, Chiang A, Chang D, Ying SY (2008) Loss of mir-146a function in hormone-refractory prostate cancer. RNA 14(3):417–424
19. Xu B, Wang N, Wang X et al (2012) MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. Prostate 72(11):1171–1178