Antibody-Conjugated Gold Nanoparticle-Based Immunosensor for Ultra-Sensitive Detection of Troponin-T

Journal of Laboratory Automation

Volumn 19, Issue 6, 2014, Pages 546-554

  Jacobs, Michael ^a   Panneer Selvam, Anjan ^a   Craven, Jon Engel ^a   Prasad, Shalini ^a  

^a The University of Texas at Dallas   (United States)

Author keywords

clinical diagnostics; gold nanoparticles; impedance spectroscopy; label free; portable biosensor

Indexed keywords

ANTIBODIES; BIOMARKERS; BIOSENSORS; CHEMICAL DETECTION; FIBER OPTIC SENSORS; GLASS; GOLD METALLOGRAPHY; METAL NANOPARTICLES; MICROELECTRODES; MOLDS; PRINTED CIRCUIT BOARDS; SPECTROSCOPY; SUBSTRATES;

CLINICAL DIAGNOSTICS; CROSS-LINKING MOLECULE; ELECTRICAL IMPEDANCE SPECTROSCOPY; IMPEDANCE SPECTROSCOPY; LABEL FREE; MICROCONTACT PRINTING TECHNIQUES; PORTABLE BIOSENSORS; STANDARD PHOTOLITHOGRAPHY;

GOLD NANOPARTICLES;

BIOLOGICAL MARKER; DIMETHYL SULFOXIDE; GOLD NANOPARTICLE; TROPONIN T; ANTIBODY; GOLD; NANOPARTICLE;

ANALYTICAL PARAMETERS; ARTICLE; CONJUGATION; CONTROLLED STUDY; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; HUMAN; IMMUNOASSAY; IMMUNOSENSOR; LIMIT OF DETECTION; MICROELECTRODE; MOLECULAR INTERACTION; PHOTOLITHOTROPH; ROBUSTNESS; SCANNING ELECTRON MICROSCOPE; SENSITIVITY ANALYSIS; BLOOD; DIAGNOSTIC USE; EVALUATION STUDY; GENETIC PROCEDURES; HEART DISEASES; PROCEDURES; SENSITIVITY AND SPECIFICITY;

ANTIBODIES; BIOLOGICAL MARKERS; BIOSENSING TECHNIQUES; GOLD; HEART DISEASES; HUMANS; NANOPARTICLES; SENSITIVITY AND SPECIFICITY; TROPONIN T;

EID: 84911935595     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068214538971     Document Type: Article

References (22)

1. Grundy S. M.,Benjamin I. J.,Burke G. L., et al.Diabetes and Cardiovascular Disease: A Statement for Healthcare Professionals from the American Heart Association.Circulation. 1999;100:1134-1146
2. Ruth E.,Urban N.,Ramsey S., et al.The Case for Early Detection.Nat. Rev. Cancer. 2003;3:243-252
3. Babuin L.,Jaffe A. S.Troponin: The Biomarker of Choice for the Detection of Cardiac Injury.Can. Med. Assoc. J. 2005;173:1191-1202
4. Lloyd-Jones D.,Adams R.,Carnethon M., et al.Heart Disease and Stroke Statistics—2009 Update: A Report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.Circulation. 2009;119:480-486
5. Saunders J. T.,Nambi V.,de Lemos J.A., et al.Cardiac Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease, Heart Failure, and Mortality in the Atherosclerosis Risk in Communities Study.Circulation. 2011;123:1367-1376
6. Pingarrón J. M.,Yáñez-Sedeño P.,González-Cortés A.Gold Nanoparticle-Based Electrochemical Biosensors.Electrochim. Acta. 2008;53:5848-5866
7. Cao X.,Ye Y.,Liu S.Gold Nanoparticle-Based Signal Amplification for Biosensing.Anal. Biochem. 2011;417:1-16
8. Yeh Y.-C.,Creran B.,Rotello V. M.Gold Nanoparticles: Preparation, Properties, and Applications in Bionanotechnology.Nanoscale. 2012;4:1871-1880
9. Roduner E.Size Matters: Why Nanomaterials Are Different.Chem. Soc. Rev. 2006;35:583-592
10. Zhang X.,Ju H.,Wang J.Electrochemical Sensors, Biosensors and Their Biomedical Applications;. Elsevier Science: New York; 2011:
11. Daniel M.-C.,Astruc D.Gold Nanoparticles: Assembly, Supramolecular Chemistry, Quantum-Size–Related Properties, and Applications toward Biology, Catalysis, and Nanotechnology.Chem. Rev. 2003;104:293-346
12. Daniels J. S.,Pourmand N.Label-Free Impedance Biosensors: Opportunities and Challenges.Electroanalysis. 2007;19:1239-1257
13. Randviir E. P.,Banks C. E.Electrochemical Impedance Spectroscopy: An Overview of Bioanalytical Applications.Anal. Methods. 2013;5:1098-1115
14. Bogomolova A.,Komarova E.,Reber K., et al.Challenges of Electrochemical Impedance Spectroscopy in Protein Biosensing.Anal. Chem. 2009;81:3944-3949
15. Wilbur J. L.,Kumar A.,Biebuyck H. A., et al.Microfabrication by Microcontact Printing of Self-Assembled Monolayers.Adv. Mater. 1994;6:600-604
16. Alom Ruiz S.,Chen C. S.Microcontact Printing: A Tool to Pattern.Soft Matter. 2007;3:168-177
17. Panneer Selvam A.,Vattipalli K. M.,Prasad S.Design of a High Sensitive Non-Faradaic Impedimetric Sensor.Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE; Piscataway, NJ;.
18. Armbruster D. A.,Pry T.Limit of Blank, Limit of Detection and Limit of Quantitation.Clin. Biochem. Rev. 2008;29:S49
19. Hassibi A.,Vikalo H.,Hajimiri A.On Noise Processes and Limits of Performance in Biosensors.J. Appl. Phys. 2007;102:014909
20. Panneer Selvam A.,Prasad S.Nanosensor Electrical Immunoassay for Quantitative Detection of NT–Pro Brain Natriuretic Peptide.Future Cardiol. 2012;9:137-147
21. Kunduru V.,Bothara M.,Grosch J., et al.Nanostructured Surfaces for Enhanced Protein Detection toward Clinical Diagnostics.Nanomed. Nanotechnol. Biol. Med. 2010;6:642-650
22. Mehrvar M.,Abdi M.Recent Developments, Characteristics, and Potential Applications of Electrochemical Biosensors.Anal. Sci. 2004;20:1113-1126