-
1
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon, B., Gordon, S.C., Lawitz, E., et al., 2011. Boceprevir for previously treated chronic HCV genotype 1 infection. N. Engl. J. Med. 364, 1207-1217.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1207-1217
-
-
Bacon, B.1
Gordon, S.C.2
Lawitz, E.3
-
2
-
-
84882876118
-
Analysis of boceprevir resistance associated amino acid variants (RAVs) in two phase 3 boceprevir clinical studies
-
Barnard, R.J., Howe, J.A., Ogert, R.A., et al., 2013. Analysis of boceprevir resistance associated amino acid variants (RAVs) in two phase 3 boceprevir clinical studies. Virology 444, 329-336.
-
(2013)
Virology
, vol.444
, pp. 329-336
-
-
Barnard, R.J.1
Howe, J.A.2
Ogert, R.A.3
-
3
-
-
13244255415
-
MUSCLE: A multiple sequence alignment method with reduced time and space complexity
-
Edgar, R.C., 2004. MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5, 113.
-
(2004)
BMC Bioinformatics
, vol.5
, pp. 113
-
-
Edgar, R.C.1
-
4
-
-
77950806408
-
New algorithms and methods to estimate maximum-likelihood phylogenies: Assessing the performance of PhyML 3.0
-
Guindon, S., Dufayard, J.F., Lefort, V., Anisimova, M., Hordijk, W., Gascuel, O., 2010. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst. Biol. 59, 307-321.
-
(2010)
Syst. Biol.
, vol.59
, pp. 307-321
-
-
Guindon, S.1
Dufayard, J.F.2
Lefort, V.3
Anisimova, M.4
Hordijk, W.5
Gascuel, O.6
-
5
-
-
84859162561
-
Clinical relevance of detectable but not quantifiable hepatitis C virus RNA during boceprevir or telaprevir treatment
-
Harrington, P.R., Zeng, W., Naeger, L.K., 2012. Clinical relevance of detectable but not quantifiable hepatitis C virus RNA during boceprevir or telaprevir treatment. Hepatology 55, 1048-1057.
-
(2012)
Hepatology
, vol.55
, pp. 1048-1057
-
-
Harrington, P.R.1
Zeng, W.2
Naeger, L.K.3
-
6
-
-
77956268467
-
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): An open-label, randomised, multicentre phase 2 trial
-
Kwo, P.Y., Lawitz, E.J., McCone, J., et al., 2010. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet 376, 705-716.
-
(2010)
Lancet
, vol.376
, pp. 705-716
-
-
Kwo, P.Y.1
Lawitz, E.J.2
McCone, J.3
-
7
-
-
77951210464
-
In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435
-
Lenz, O., Verbinnen, T., Lin, T.I., et al., 2010. In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435. Antimicrob. Agents Chemother. 54, 1878-1887.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 1878-1887
-
-
Lenz, O.1
Verbinnen, T.2
Lin, T.I.3
-
8
-
-
84879795584
-
Long-term clearance of hepatitis C virus following interferon alpha-2b or peginterferon alpha-2b, alone or in combination with ribavirin
-
Manns, M.P., Pockros, P.J., Norkrans, G., et al., 2013. Long-term clearance of hepatitis C virus following interferon alpha-2b or peginterferon alpha-2b, alone or in combination with ribavirin. J. Viral Hepat. 20, 524-529.
-
(2013)
J. Viral Hepat.
, vol.20
, pp. 524-529
-
-
Manns, M.P.1
Pockros, P.J.2
Norkrans, G.3
-
9
-
-
15644380122
-
Long-term histologic improvement and loss of detectable intrahepatic HCV RNA in patients with chronic hepatitis C and sustained response to interferon-alpha therapy
-
Marcellin, P., Boyer, N., Gervais, A., et al., 1997. Long-term histologic improvement and loss of detectable intrahepatic HCV RNA in patients with chronic hepatitis C and sustained response to interferon-alpha therapy. Ann. Intern. Med. 127, 875-881.
-
(1997)
Ann. Intern. Med.
, vol.127
, pp. 875-881
-
-
Marcellin, P.1
Boyer, N.2
Gervais, A.3
-
10
-
-
84878036817
-
Resistance-associated amino acid variants associated with boceprevir plus pegylated interferon-alpha2b and ribavirin in patients with chronic hepatitis C in the SPRINT-1 trial
-
Ogert, R.A., Howe, J.A., Vierling, J.M., et al., 2013. Resistance-associated amino acid variants associated with boceprevir plus pegylated interferon-alpha2b and ribavirin in patients with chronic hepatitis C in the SPRINT-1 trial. Antiviral Ther. 18, 387-397.
-
(2013)
Antiviral Ther.
, vol.18
, pp. 387-397
-
-
Ogert, R.A.1
Howe, J.A.2
Vierling, J.M.3
-
11
-
-
84865494240
-
Factors that predict response of patients with HCV Infection to boceprevir
-
Poordad, F., Bronowicki, J.P., Gordon, S.C., et al., 2012. Factors that predict response of patients with HCV Infection to boceprevir. Gastroenterology 143, 608-618.
-
(2012)
Gastroenterology
, vol.143
, pp. 608-618
-
-
Poordad, F.1
Bronowicki, J.P.2
Gordon, S.C.3
-
12
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad, F., McCone, J., Bacon, B.R., et al., 2011. Boceprevir for untreated chronic HCV genotype 1 infection. N. Engl. J. Med. 364, 1195-1206.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.R.3
-
13
-
-
84879218816
-
Durability of SVR in chronic hepatitis C patients treated with peginterferon-α2a/ribavirin in combination with a direct-acting antiviral
-
Rutter, K., Hofer, H., Beinhardt, S., et al., 2013. Durability of SVR in chronic hepatitis C patients treated with peginterferon-α2a/ribavirin in combination with a direct-acting antiviral. Aliment. Pharmacol. Ther. 38, 118-123.
-
(2013)
Aliment. Pharmacol. Ther.
, vol.38
, pp. 118-123
-
-
Rutter, K.1
Hofer, H.2
Beinhardt, S.3
-
14
-
-
52649168519
-
Boceprevir (b) combination therapy in null responders (NR): Response dependent on interferon responsiveness
-
Schiff, E., Poordad, F., Jacobson, I., et al., 2008. Boceprevir (b) combination therapy in null responders (NR): response dependent on interferon responsiveness. J. Hepatol. 48 (Suppl. 2), S46.
-
(2008)
J. Hepatol.
, vol.48
, pp. S46
-
-
Schiff, E.1
Poordad, F.2
Jacobson, I.3
-
15
-
-
79251561245
-
Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus
-
Shimakami, T., Welsch, C., Yamane, D., et al., 2011. Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus. Gastroenterology 140, 667-675.
-
(2011)
Gastroenterology
, vol.140
, pp. 667-675
-
-
Shimakami, T.1
Welsch, C.2
Yamane, D.3
-
16
-
-
84879683134
-
Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials
-
Sullivan, J.C., De Meyer, S., Bartels, D.J., et al., 2013. Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials. Clin. Infect. Dis. 57, 221-229.
-
(2013)
Clin. Infect. Dis.
, vol.57
, pp. 221-229
-
-
Sullivan, J.C.1
De Meyer, S.2
Bartels, D.J.3
-
17
-
-
73149113353
-
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients
-
Susser, S., Welsch, C., Wang, Y., et al., 2009. Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. Hepatology 50, 1709-1718.
-
(2009)
Hepatology
, vol.50
, pp. 1709-1718
-
-
Susser, S.1
Welsch, C.2
Wang, Y.3
-
18
-
-
78049476361
-
A sustained virologic response is durable in patients with chronic hepatitis C treated with peginterferon alfa-2a and ribavirin
-
Swain, M.G., Lai, M.Y., Shiffman, M.L., et al., 2010. A sustained virologic response is durable in patients with chronic hepatitis C treated with peginterferon alfa-2a and ribavirin. Gastroenterology 139, 1593-1601.
-
(2010)
Gastroenterology
, vol.139
, pp. 1593-1601
-
-
Swain, M.G.1
Lai, M.Y.2
Shiffman, M.L.3
-
19
-
-
38749115754
-
Characterization of resistance mutations against HCV ketoamide protease inhibitors
-
Tong, X., Bogen, S., Chase, R., et al., 2008. Characterization of resistance mutations against HCV ketoamide protease inhibitors. Antiviral Res. 77, 177-185.
-
(2008)
Antiviral Res.
, vol.77
, pp. 177-185
-
-
Tong, X.1
Bogen, S.2
Chase, R.3
-
20
-
-
33646036163
-
Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034
-
Tong, X., Chase, R., Skelton, A., Chen, T., Wright-Minogue, J., Malcolm, B.A., 2006. Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034. Antiviral Res. 70, 28-38.
-
(2006)
Antiviral Res.
, vol.70
, pp. 28-38
-
-
Tong, X.1
Chase, R.2
Skelton, A.3
Chen, T.4
Wright-Minogue, J.5
Malcolm, B.A.6
|