Expanding our understanding of respiratory microbiota in cystic fibrosis

Annals of the American Thoracic Society

Volumn 11, Issue 7, 2014, Pages 1084-1085

  LiPuma, John J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACHROMOBACTER XYLOSOXIDANS; BRONCHITIS; BURKHOLDERIA CEPACIA COMPLEX; CYSTIC FIBROSIS; DISEASE COURSE; DNA SEQUENCE; EDITORIAL; GENE THERAPY; HAEMOPHILUS INFLUENZAE; HUMAN; LUNG DISEASE; LUNG FUNCTION; MICROBIAL COMMUNITY; MICROFLORA; NONHUMAN; PSEUDOMONAS AERUGINOSA; RESPIRATORY FAILURE; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA; BACTERIAL INFECTIONS; COMPREHENSION; FEMALE; GENETICS; LUNG; MALE; MICROBIOLOGY; PROCEDURES; PROGNOSIS; RESPIRATORY TRACT INFECTIONS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX;

CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR;

BACTERIAL INFECTIONS; COMPREHENSION; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE PROGRESSION; FEMALE; GENETIC THERAPY; HUMANS; LUNG; MALE; MICROBIOTA; PROGNOSIS; RESPIRATORY TRACT INFECTIONS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX;

EID: 84911909342     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201407-303ED     Document Type: Editorial

References (16)

1. LiPuma JJ. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev 2010;23:299-323.
2. Coenye T, Goris J, Spilker T, Vandamme P, LiPuma JJ. Characterization of unusual bacteria isolated from respiratory secretions of cystic fibrosis patients and description of Inquilinus limosus gen. nov., sp. nov. J Clin Microbiol 2002;40:2062-2069.
3. Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Bruce KD. Characterization of bacterial community diversity in cystic fibrosis lung infections by use of 16s ribosomal DNA terminal restriction fragment length polymorphism profiling. J Clin Microbiol 2004;42:5176-5183.
4. Harris JK, De Groote MA, Sagel SD, Zemanick ET, Kapsner R, Penvari C, Kaess H, Deterding RR, Accurso FJ, Pace NR. Molecular identification of bacteria in bronchoalveolar lavage fluid from children with cystic fibrosis. Proc Natl Acad Sci USA 2007;104:20529-20533.
5. Cox MJ, Allgaier M, Taylor B, Baek MS, Huang YJ, Daly RA, Karaoz U, Andersen GL, Brown R, Fujimura KE, et al. Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients. PLoS ONE 2010;5:e11044.
6. Klepac-Ceraj V, Lemon KP, Martin TR, Allgaier M, Kembel SW, Knapp AA, Lory S, Brodie EL, Lynch SV, Bohannan BJ, et al. Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa. Environ Microbiol 2010;12:1293-1303.
7. Stressmann FA, Rogers GB, van der Gast CJ, Marsh P, Vermeer LS, Carroll MP, Hoffman L, Daniels TW, Patel N, Forbes B, et al. Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience. Thorax 2012;67:867-873.
8. van der Gast CJ, Walker AW, Stressmann FA, Rogers GB, Scott P, Daniels TW, Carroll MP, Parkhill J, Bruce KD. Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities. ISME J 2011;5:780-791.
9. Zhao J, Schloss PD, Kalikin LM, Carmody LA, Foster BK, Petrosino JF, Cavalcoli JD, VanDevanter DR, Murray S, Li JZ, et al. Decade-long bacterial community dynamics in cystic fibrosis airways. Proc Natl Acad Sci USA 2012;109:5809-5814.
10. Carmody LA, Zhao J, Schloss PD, Petrosino JF, Murray S, Young VB, Li JZ, LiPuma JJ. Changes in cystic fibrosis airway microbiota at pulmonary exacerbation. Ann Am Thorac Soc 2013;10:179-187.
11. Goddard AF, Staudinger BJ, Dowd SE, Joshi-Datar A, Wolcott RD, Aitken ML, Fligner CL, Singh PK. Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota. Proc Natl Acad Sci USA 2012;109:13769-13774.
12. Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Kehagia V, Connett GJ, Bruce KD. Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism analysis to compare bacterial communities in sputum and mouthwash samples from patients with cystic fibrosis. J Clin Microbiol 2006;44:2601-2604.
13. Whiteson KL, Bailey B, Bergkessel M, Conrad D, Delhaes L, Felts B, Harris JK, Hunter R, Lim YW, Maughan H, et al. The upper respiratory tract as a microbial source for pulmonary infections in cystic fibrosis: parallels from island biogeography. Am J Respir Crit Care Med 2014;189:1309-1315.
14. VanDevanter DR, LiPuma JJ. Microbial diversity in the cystic fibrosis airways: where is thy sting? Future Microbiol 2012;7:801-803.
15. Brown PS, Pope CE, Marsh RL, Qin X, McNamara S, Gibson R, Burns JL, Deutsch G, Hoffman LR. Directly sampling the lung of a young child with cystic fibrosis reveals diverse microbiota. Ann Am Thorac Soc 2014;11: 1049-1055.
16. van der Gast CJ, Cuthbertson L, Rogers GB, Pope C, Marsh RL, Redding GJ, Bruce KD, Chang AB, Hoffman LR. Three clinically distinct pediatric airway infections share a common core microbiota. Ann Am Thorac Soc 2014;11:1309-1048.