The association between cannabis use, mental illness, and suicidal behavior: What is the role of hopelessness?

Frontiers in Psychiatry

Volumn 4, Issue OCT, 2013, Pages

  Serafini, Gianluca ^a   Pompili, Maurizio ^a   Innamorati, Marco ^a   Temple, Elizabeth C ^b   Amore, Mario ^c   Borgwardt, Stefan ^d   Girardi, Paolo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF BALLARAT   (Australia)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS;

ARTICLE; BEHAVIOR CHANGE; BRAIN FUNCTION; CANNABIS USE; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE CONTROL; DISEASE EXACERBATION; EMOTIONAL DISORDER; FUNCTIONAL ASSESSMENT; HEALTH PROGRAM; HIGH RISK POPULATION; HOPELESSNESS; HUMAN; MENTAL DISEASE; OUTCOME ASSESSMENT; PREDICTION; RISK ASSESSMENT; RISK FACTOR; SOCIAL INTERACTION; SUICIDAL BEHAVIOR; SUICIDAL IDEATION;

EID: 84911897980     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2013.00125     Document Type: Article

References (58)

1. EMCCDA. The State of the Drug Problems in Europe. Lisboa: EMCDDA (2006).
2. Hall W, Degenhardt L. Adverse health effects of nonmedical cannabis use. Lancet (2009) 374:1383-91. doi: 10.1016/S0140-6736(09)61037-0
3. Adlaf EM, Begin P, Sawka E. Canadian Addiction Survey: A National Survey of Canadians' Use of Alcohol and Other Drugs: Prevalence of Use and Related Harms: Detailed Report. Ottawa, ON: Canadian Centre on Substance Abuse (2005).
4. Moore THM, Zammit S, Lingford-Hughes A. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet (2007) 370:319-28. doi: 10.1016/S0140-6736(07)61162-3
5. Rapp C, Bugra H, Riecher-Rössler A, Tamagni C, Borgwardt S. Effects of cannabis use on human brain structure in psychosis: a systematic review combining in vivo structural neuroimaging and post mortem studies. Curr Pharm Des (2012) 18:5070-80. doi: 10.2174/138161212802884861
6. Martín-Santos R, Fagundo AB, Crippa JA, Atakan Z, Bhattacharyya S, Allen P, et al. Neuroimaging in cannabis use: a systematic review of the literature. Psychol Med (2010) 40:383-98. doi: 10.1017/ S0033291709990729
7. Patton GC, Coffey C, Sawyer SM, Viner RM, Haller KM, Vos T, et al. Global patterns of mortality in young people: a systematic review of the literature. Lancet (2009) 374:881-92. doi: 10.1016/ S0140-6736(09)60741-8
8. Maharajh HD, Konings M. Cannabis and suicidal behaviour among adolescents: a pilot study from Trinidad. ScientifcWorldJournal (2005) 5:576-85. doi: 10.1100/tsw.2005.79
9. Price C, Hemmingsson T, Lewis G, Zammit S, Allebeck P. Cannabis and suicide: longitudinal study. Br J Psychiatry (2009) 195:492-7. doi: 10.1192/bjp. bp.109.065227
10. Lynskey MT, Glowinski AL, Todorov AA, Bucholz KK, Madden PA, Nelson EC, et al. Major depressive disorder, suicidal ideation, and suicide attempt in twins discordant for cannabis dependence and early-onset cannabis use. Arch Gen Psychiatry (2004) 61:1026-32. doi: 10.1001/archpsyc.61.10.1026
11. Beautrais AL, Joyce PR, Mulder RT. Cannabis abuse and serious suicide attempts. Addiction (1999) 94:1155-64 doi: 10.1046/j.1360-0443.1999.94811555.x
12. van Ours JC, Williams J, Fergusson D, Horwood LJ. Cannabis use and suicidal ideation. J Health Econ (2013) 32:524-37. doi: 10.1016/j. jhealeco.2013.02.002
13. van Ours JC, Williams J. Cannabis use and mental health problems. J Appl Econ (2011) 26:1137-56. doi: 10.1002/jae.1182
14. Henquet C, Krabbendam L, de Graaf R, ten Have M, van Os J. Cannabis use and the expression of mania in the general population. J Affect Disord (2006) 95:103-10. doi: 10.1016/j.jad.2006.05.002
15. Serafni G, Pompili M, Innamorati M, Rihmer Z, Sher L, Girardi P. Can cannabis increase the suicide risk in psychosis? A critical review. Curr Pharm Des (2012) 18:5165-87. doi: 10.2174/138161212802884663
16. van Ours JC, Williams J. The effects of cannabis use on physical and mental health. J Health Econ (2012) 31:564-77. doi: 10.1016/j.jhealeco.2012.04.003
17. Winter-van Rossum I, Boomsma MM, Tenback DE, Reed C, van Os J. [The infuence of cannabis on the course of bipolar disorder: a longitudinal analysis]. Tijdschr Psychiatr (2010) 52:287-98.
18. Cerullo MA, Strakowski SM. The prevalence and signifcance of substance use disorders in bipolar type I and II disorder. Subst Abuse Treat Prev Policy (2007) 2:29. doi: 10.1186/1747-597X-2-29
19. Marshall M, Rathbone J. Early intervention for psychosis. Cochrane Database Syst Rev (2011) 6:CD004718.
20. Pacek LR, Martins SS, Crum RM. The bidirectional relationships between alcohol, cannabis, co-occurring alcohol and cannabis use disorders with major depressive disorder: results from a national sample. J Affect Disord (2013) 148:188-95. doi: 10.1016/j. jad.2012.11.059
21. Foti DJ, Kotov R, Guey LT, Bromet EJ. Cannabis use and the course of schizophrenia: 10-year follow-up after frst hospitalization. Am J Psychiatry (2010) 167:987-93. doi: 10.1176/appi.ajp.2010.09020189
22. Malmberg M, Overbeek G, Monshouwer K, Lammers J, Vollebergh WA, Engels RC. Substance use risk profles and associations with early substance use in adolescence. J Behav Med (2010) 33:474-85. doi: 10.1007/s10865-010-9278-4
23. Sanches RF, Marques JM. Cannabis and mood. Rev Bras Psiquiatr (2010) 32:173-80. doi: 10.1590/ S1516-44462010000200014
24. Calabria B, Degenhardt L, Hall W, Lynskey M. Does cannabis use increase the risk of death? Systematic review of epidemiological evidence on adverse effects of cannabis use. Drug Alcohol Rev (2010) 29:318-30. doi: 10.1111/j.1465-3362.2009.00149.x
25. Rey JM, Martin A, Krabman P. Is the party over? Cannabis and juvenile psychiatric disorder: the past 10 years. J Am Acad Child Adolesc Psychiatry (2004) 43:1194-205. doi: 10.1097/01. chi.0000135623.12843.60
26. Raphael B, Wooding S, Stevens G, Connor J. Comorbidity: cannabis and complexity. J Psychiatr Pract (2005) 11:161-76. doi: 10.1097/00131746-200505000-00004
27. Pompili M, Serafni G, Innamorati M, Biondi M, Siracusano A, Di Giannantonio M, et al. Substance abuse and suicide risk among adolescents. Eur Arch Psychiatry Clin Neurosci (2012) 262:469-85. doi: 10.1007/s00406-012-0292-0
28. Pompili M, Innamorati M, Rihmer Z, Gonda X, Serafni G, Akiskal H, et al. Cyclothymic-depressiveanxious temperament pattern is related to suicide risk in 346 patients with major mood disorders. J Affect Disord (2012) 136:405-11. doi: 10.1016/j. jad.2011.11.011
29. Pompili M, Serafni G, Innamorati M, Lester D, Shrivastava A, Girardi P, et al. Suicide risk in frst episode psychosis: a selective review of the current literature. Schizophr Res (2011) 129:1-11. doi: 10.1016/j.schres.2011.03.008
30. Beck AT, Brown G, Steer RA. Prediction of eventual suicide in psychiatric inpatients by clinical ratings of hopelessness. J Consult Clin Psychol (1989) 57:309-10 doi: 10.1037/0022-006X.57.2.309
31. Brown GK, Beck AT, Steer RA, Grisham JR. Risk factors for suicide in psychiatric outpatients. A 20-year prospective study. J Consult Clin Psychol (2000) 68:371-7. doi: 10.1037/0022-006X.68.3.371
32. O'Connor RC, Fraser L, Whyte M, MacHale S, Masterton G. A comparison of specifc positive future expectancies and global hopelessness as predictors of suicidal ideation in a prospective study of repeat self-harmers. J Affect Disord (2008) 110:207-14. doi: 10.1016/j.jad.2008.01.008
33. Kuo WH, Gallo JJ, Eaton WW. Hopelessness, depression, substance disorder, and suicidality - a 13-year community-based study. Soc Psychiatry Psychiatr Epidemiol (2004) 39:497-501. doi: 10.1007/ s00127-004-0775-z
34. Jaffee WB, D'Zurilla TJ. Personality, problem solving, and adolescent substance use. Behav Ther (2009) 40:93-101. doi: 10.1016/j.beth.2008.03.001
35. Hyman SM, Sinha R. Stress-related factors in cannabis use and misuse: implications for prevention and treatment. J Subst Abuse Treat (2009) 36:400-13. doi: 10.1016/j.jsat.2008.08.005
36. Iliceto P, Pompili M, Girardi P, Lester D, Vincenti C, Rihmer Z, et al. Hopelessness, temperament, and health perception in heroin addicts. J Addict Dis (2010) 29:352-8. doi: 10.1080/10550887.2010.489448
37. Pompili M, Rihmer Z, Akiskal H, Amore M, Gonda X, Innamorati M, et al. Temperaments mediate suicide risk and psychopathology among patients with bipolar disorders. Compr Psychiatry (2012) 53:280-5. doi: 10.1016/j.comppsych.2011.04.004
38. Rihmer A, Rozsa S, Rihmer Z, Gonda X, Akiskal KK, Akiskal HS. Affective temperaments, as measured by TEMPS-A, among nonviolent suicide attempte r s. J Affect Disord (2009) 116:18-22. doi: 10.1016/j. jad.2008.10.024
39. Serafni G, Pompili M, Innamorati M, Fusar-Poli P, Akiskal HS, Rihmer Z, et al. Affective temperamental profles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders. J Affect Disord (2011) 129:47-55. doi: 10.1016/j.jad.2010.07.020
40. Gonda X, Rihmer Z, Zsombok T, Bagdy G, Akiskal KK, Akiskal HS. The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-A. J Affect Disord (2006) 91:125-31. doi: 10.1016/j. jad.2005.12.048
41. Roane BM, Taylor DJ. Adolescent insomnia as a risk factor for early adult depression and substance abuse. Sleep (2008) 31:1351-6.
42. Serafni G, Pompili M, Elena Seretti M, Stefani H, Palermo M, Coryell W, et al. The role of infammatory cytokines in suicidal behavior: a systematic review. Eur Neuropsychopharmacol (2013) (in press). doi: 10.1016/j.euroneuro.2013.06.002
43. McManama O, Brien KH, Berzin SC. Examining the impact of psychiatric diagnosis and comorbidity on the medical lethality of adolescent suicide attempts. Suicide Life Threat Behav (2012) 42:437-44. doi: 10.1111/j.1943-278X.2012.00102.x
44. Berger G, Fraser R, Carbone S, McGorry P. Emerging psychosis in young people - Part 1 - key issues for detection and assessment. Aust Fam Physician (2006) 35:315-21.
45. Atakan Z, Bhattacharyya S, Allen P, Martín-Santos R, Crippa JA, Borgwardt SJ, et al. Cannabis affects people differently: inter-subject variation in the psychotogenic effects of D9-tetrahydrocannabinol: a functional magnetic resonance imaging study with healthy volunteers. Psychol Med (2012) 43(6):1255-67 doi: 10.1017/S0033291712001924
46. Denier N, Walter M, Bendfeldt K, Lang U, Borgwardt S. Resting state abnormalities in psychosis compared to acute cannabinoids and opioids challenges: a systematic review of functional imaging studies. Curr Pharm Des (2012) 18:5081-92. doi: 10.2174/138161212802884717
47. Chistiakov DA, Kekelidze ZI, Chekhonin VP. Endophenotypes as a measure of suicidality. J Appl Genet (2012) 53:389-413. doi: 10.1007/ s13353-012-0113-1
48. Fontes MA, Bolla KI, Cunha PJ, Almeida PP, Jungerman F, Laranjeira RR, et al. Cannabis use before age 15 and subsequent executive functioning. Br J Psychiatry (2011) 198:442-7. doi: 10.1192/ bjp.bp.110.077479
49. Beautrais A, Collings S, Ehrhardt P. Suicide Prevention: A Review of Evidence of Risk and Protective Factors, and Points of Effective Intervention. Wellington: Ministry of Health (2005).
50. Bridge J, Goldstein T, Brent D. Adolescent suicide and suicidal behavior. J Child Psychol Psychiatry (2006) 47:372-94. doi: 10.1111/j.1469-7610.2006.01615.x
51. Reinherz HZ, Paradis AD, Giaconia RM, Stashwick CK, Fitzmaurice G. Childhood and adolescent predictors of major depression in the transition to adulthood. Am J Psychiatry (2003) 160:2141-7. doi: 10.1176/appi.ajp.160.12.2141
52. Taliaferro LA, Borowsky IW. Perspective: physician education: a promising strategy to prevent adolescent suicide. Acad Med (2011) 86:342-7. doi: 10.1097/ACM.0b013e31820984ad
53. Beck AT, Weissman A, Lester DLT. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol (1974) 42:861-5. doi: 10.1037/ h0037562
54. Klonsky DE, Kotov R, Bakst S, Rabinowitz J, Bromet EJ. Hopelessness as a predictor of attempted suicide among first admission patients with psychosis: a 10-year cohort study. Suicide Life Threat Behav (2012) 42:1-10. doi: 10.1111/j.1943-278X.2011.00066.x
55. Tobler NS, Stratton HH. Effectiveness of schoolbased drug prevention programs: a meta-analysis of the research. J Prim Prev (1997) 18:71-128. doi: 10.1023/A:1024630205999
56. Tobler NS, Roona MR, Ochshorn P, Marshall DG, Streke AV, Stackpole KM. School-based adolescent drug prevention programs: 1998 metaanalysis. J Prim Prev (2000) 20:275-336. doi: 10.1023/A:1021362620740
57. Porath-Waller AJ, Beasley E, Beirness DJ. A metaanalyt ic rev iew of school-based prevention for can -nabis use. Health Educ Behav (2010) 37:709-23. doi: 10.1177/1090198110361315
58. Wu P, Hoven CW, Liu X, Cohen P, Fuller CJ, Shaffer D. Substance use, suicidal ideation and attempts in children and adolescents. Suicide Life Threat Behav (2004) 34:408-20. doi: 10.1521/ suli.34.4.408.53733